Santa Cruz Adventure Vacations

Book a Adventure Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

4 Night Adventure vacations in Santa Cruz

Price found within the past 48 hours. Click for updated prices.
Casa Vida
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Don't see what you're looking for?
See all available trips from Columbus to Santa Cruz
View all trips

Find awesome Santa Cruz adventure vacations

How can I book the best Santa Cruz adventure trips?

Choose your own adventure in Santa Cruz, whether that’s a white-knuckle experience or a weekend walk. Read the reviews of the adventures that have gone before to be sure your chosen stay is your idea of fun.

How can I plan the perfect Santa Cruz family adventure vacation?

Adventure awaits when you select the family-friendly filter. There’s plenty of excitement for all ages in Santa Cruz. Just make sure to check your chosen escapade is within the realms of can-do for the whole clan and will have the whole team grinning.

Can I book all-inclusive Santa Cruz adventure vacation packages?

By refining your filters, you can explore all-amazing, all-adventurous, all-inclusive vacation packages. Amp up the extravagance with a few more filters too. Pick pristine pools, sensational spas, or wondrous waterparks for a sensational adventure getaway.

Why should I book a Santa Cruz adventure vacation for couples?

Book a Santa Cruz couples adventure vacation for the ultimate in romance and memory-making. Stunning scenery, heart-racing happenings, and the grandeur of the great outdoors—it’s the best way to bond.

How can I find the best deals on adventure packages in Santa Cruz?

It’s easy to unleash fabulously affordable adventures. Enter the dates for your caper, then sort your search results by price or deals.

Can I book an adventure vacation package in Santa Cruz with free cancellation and/or flexible dates?

Yes! When you’re searching for a great getaway, filter by payment option for free cancellation, so a change of plans won’t mess up your adventures. You’ll find buy now, pay later options, too, for full-on flexibility.

Why should I book a Santa Cruz adventure trip with Expedia?

Adventure, airfare, accommodation, ATOL protection, and activities—all on one site. And that’s just the benefits that begin with A.

Top Adventure Santa Cruz Hotels

Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
  • 6 min drive from Ventura Mall
Stay at this 4-star family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...
7.4/10 Good! (92 reviews)
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING"

Reviewed on Aug 14, 2021

Buganvillas Hotel Suites & Spa
Casa Vida

Casa Vida

3.5 out of 5
Condominio Club Campestre, Kilometro 13 doble via La Guardia, Santa Cruz, Santa
  • 20 min drive from Ventura Mall
Stay at this 3.5-star family-friendly vacation home in Santa Cruz. Enjoy free WiFi, free parking, and private hot tubs.
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

Reviewed on Sep 28, 2017

Casa Vida
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
  • 13 min walk from Ventura Mall
$118 nightly
The price is $118 total per night from Oct 17 to Oct 18
$118 total
Oct 17 - Oct 18
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (331 reviews)
"Hotel was excellent. Staff excellent, check in good and bar resturant really good. room was good and clean"

Reviewed on Oct 3, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.