Find hotels near Santo Spirito Hospital, Rome from $100

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Compare 14,936 hotels close to Santo Spirito Hospital with room rates, reviews, and availability. Most hotels are fully refundable.

Property entrance
San Pietro Boutique Rooms

San Pietro Boutique Rooms

Prati, 0.3 mi from Santo Spirito Hospital
10.0 out of 10, Exceptional, (912)
"Amazing experience! Great location and very friendly staff!"
United States
Daniel
$141 nightly
The price is $166
Jan 7 - Jan 8, 2026
Total with taxes and fees
San Pietro Boutique Rooms
Panoramic Studio Suite, Terrace | Minibar, in-room safe, individually decorated, individually furnished
Passpartout Boutique Palace

Passpartout Boutique Palace

0.3 mi from Santo Spirito Hospital
9.8 out of 10, Exceptional, (245)
"Excellent location, great dining options nearby, modern boutique hotel."
Canada
Matthew
$125 nightly
The price is $154
Dec 14 - Dec 15
Total with taxes and fees
Passpartout Boutique Palace
Standard Double Room | Premium bedding, free minibar, in-room safe, desk
Corso Vittorio 308

Corso Vittorio 308

0.2 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (63)
"The staff and property made for a 5 star stay."
United States
Brady
Corso Vittorio 308
Panoramic Triple Room | In-room safe, desk, soundproofing, iron/ironing board
Charme 308

Charme 308

0.2 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (94)
"Amazing hotel!"
United Kingdom
Anonymous traveler
$127 nightly
The price is $157
Dec 9 - Dec 10
Total with taxes and fees
Charme 308
Lobby
Navona Street Hotel

Navona Street Hotel

3.0 star property
0.2 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (268)
"Staff was very friendly and helpful. "
United States
Eli M
$126 nightly
The price is $153
Dec 14 - Dec 15
Total with taxes and fees
Navona Street Hotel
Classic Quadruple Room | Hypo-allergenic bedding, minibar, in-room safe, desk
Hotel Sant' Anna

Hotel Sant' Anna

3.0 star property
0.3 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (322)
"Wonderful location, very helpful service and staff!"
United States
Stephen
$198 nightly
The price is $232
Dec 18 - Dec 19
Total with taxes and fees
Hotel Sant' Anna
Junior Suite | Desk, laptop workspace, soundproofing, free WiFi
Porta Castello Suites

Porta Castello Suites

0.3 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (177)
"Great home with a perfect view from ever room. The location was very convenient and walking distance to shops, restaurants and beach. The small cafe/market downstairs was also great and convenient. Breakfast was a bonus! Would definitely stay here again! "
United States
Jessica
$76 nightly
The price is $100
Dec 10 - Dec 11
Total with taxes and fees
Porta Castello Suites
Lobby sitting area
Le Suite Del Barone

Le Suite Del Barone

0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (414)
"We enjoyed our stay very much. "
Germany
Ulrike
$120 nightly
The price is $148
Dec 22 - Dec 23
Total with taxes and fees
Le Suite Del Barone
Junior Suite, Balcony | Balcony
Passepartout

Passepartout

Parione, 0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (282)
"Loved the location, in the heart of Rome"
Canada
dina
$124 nightly
The price is $149
Dec 9 - Dec 10
Total with taxes and fees
Passepartout
Classic Double Room | Hypo-allergenic bedding, minibar, soundproofing, iron/ironing board
Vatican Jubilee

Vatican Jubilee

Prati, 0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (55)
"Great place!"
United States
Hugo
$91 nightly
The price is $115
Jan 7 - Jan 8, 2026
Total with taxes and fees
Vatican Jubilee
Double Room | Minibar, in-room safe, desk, free WiFi
Cassiodoro 19

Cassiodoro 19

Prati, 0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (523)
"Excelente trato"
Mexico
Eddy Alejandro
$133 nightly
The price is $160
Jan 6 - Jan 7, 2026
Total with taxes and fees
Cassiodoro 19
Superior Double Room, 1 Double Bed | View from room
La Maison dell'Orologio

La Maison dell'Orologio

0.3 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (256)
"Room was cleaned well"
United States
Augusta
$95 nightly
The price is $118
Dec 14 - Dec 15
Total with taxes and fees
La Maison dell'Orologio
View from property
Palazzo Medusa

Palazzo Medusa

0.2 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (285)
"Great location, friendly and helpful staff, spotless room - I highly recommend!!!"
United Kingdom
James
$103 nightly
The price is $125
Dec 21 - Dec 22
Total with taxes and fees
Palazzo Medusa
1 bedroom, premium bedding, in-room safe, desk
Capricci Romani

Capricci Romani

0.3 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (361)
"Really enjoyed the location and staff. Breakfast was amazing. "
United States
Raquel
$112 nightly
The price is $134
Jan 5 - Jan 6, 2026
Total with taxes and fees
Capricci Romani
Staircase
All’Orologio

All’Orologio

0.3 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (167)
"Very happy with my choice… staff were excellent communicators before and during my stay, loved the location. "
Canada
Andrew
$125 nightly
The price is $152
Dec 14 - Dec 15
Total with taxes and fees
All’Orologio
Deluxe Double Room, River View (Breakfast at Navona Street Hotel) | View from room
B&B Rome River Inn

B&B Rome River Inn

0.2 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (505)
"Staff very helpful Good location Enjoyed stay"
Australia
Richard
$106 nightly
The price is $130
Dec 9 - Dec 10
Total with taxes and fees
B&B Rome River Inn
Suite | Premium bedding, down comforters, in-room safe, desk
The Pope's Window

The Pope's Window

0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (410)
"Good location and spacious room"
Canada
Qing
$88 nightly
The price is $111
Dec 9 - Dec 10
Total with taxes and fees
The Pope's Window
Interior
Residenza Adriana

Residenza Adriana

0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (192)
"It was very nice!"
United States
Benjamin
$99 nightly
The price is $123
Dec 9 - Dec 10
Total with taxes and fees
Residenza Adriana
Property entrance
HiSuiteROME

HiSuiteROME

0.3 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (395)
"Clean room, amenities, and the staff were Excellent!! "
United States
Diana
$169 nightly
The price is $200
Dec 11 - Dec 12
Total with taxes and fees
HiSuiteROME
Exterior
Now Apartments

Now Apartments

0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (58)
"Such a great apartment in a very cool spot, access to lots of restaurants and shopping. Really loved our stay and would revisit. "
Australia
Renee
$248 nightly
The price is $287
Dec 10 - Dec 11
Total with taxes and fees
Now Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Spirito Hospital Hotel Reviews

Grand Hotel Olympic

Grand Hotel Olympic

10/10 Excellent
"Good Option in Rome"
Rosa 2-night trip
Posted 19 hours ago
Grand Hotel Olympic

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Vittorio Emanuele II Bridge

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Accademia di Storia dell‘Arte Sanitaria

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