Mission Valley Vacations from $223

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Your Mission Valley Vacation

With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.

The Latest Mission Valley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Urban Boutique Hotel

Urban Boutique Hotel

Downtown San Diego
Save 100% on your flight
$223
per person
Dec 8 - Dec 11
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (1,240 reviews)
Nice hotel in the heart of little Italy! Bed was comfy, decent water pressure, and about a 15 min walk from all the places you’d want to visit in DT SD. Would definitely recommend.

Reviewed on Sep 29, 2026

The Sofia Hotel

The Sofia Hotel

Downtown San Diego
$228
per person
Dec 8 - Dec 11
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (2,663 reviews)
Paradise Point Resort & Spa

Paradise Point Resort & Spa

Mission Bay
Save 100% on your flight
$314
per person
Dec 8 - Dec 11
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.8/10 Excellent! (2,887 reviews)
Bahia Resort Hotel

Bahia Resort Hotel

Central Mission Beach
Save 100% on your flight
$442
per person
Dec 4 - Dec 9
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (2,417 reviews)
I had to cut my stay short due to a family illness and they were very gracious in refunding my room for 1 day

Reviewed on Oct 1, 2026

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Mission Valley
Save 100% on your flight
$277
per person
Dec 8 - Dec 11
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (3,102 reviews)
Everything was truly delightful, except the wifi that is used to operate the T.V. never worked. Outside of that, the hotel is centrally located and very reasonably priced.

Reviewed on Oct 1, 2026

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

3 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

A pier extending into calm waters with people on it and a sandy beach with seaweed and a few individuals.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

A sandy beach with a lifeguard tower, ocean waves, and people in the distance.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

A lively street scene with outdoor seating at various bars and restaurants, including 'The Field' and 'Sloppy Joe's'.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

1 out of top 10 points of interest in this area

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Mission Valley Hotel Deals

Best Western Seven Seas

Best Western Seven Seas

411 Hotel Circle South San Diego CA
$85 nightly
$97 total
Oct 4 - Oct 5
Total with taxes and fees
8/10 Very Good! (3,949 reviews)
"The place needs to be updated, looks and feels old. Might be clean but felt disgusting. For the cost per night, I expected better. My room smelled very strongly of mold. When I sent a message, they just offered house keeping to "help with the smell". I would not stay here again at this price ..."

Reviewed on Oct 1, 2026

Best Western Seven Seas
Handlery Hotel

Handlery Hotel

950 Hotel Cir N San Diego CA
$103 nightly
$119 total
Oct 5 - Oct 6
Total with taxes and fees
8.4/10 Very Good! (2,980 reviews)
"I like staying here .I feel safe and I have restaurants close to hotel.Everything was great only a strong order of dust in restroom .I would stay here again"

Reviewed on Oct 1, 2026

Handlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

543 Hotel Circle S San Diego CA
$88 nightly
$102 total
Oct 19 - Oct 20
Total with taxes and fees
Days Inn by Wyndham San Diego Hotel Circle
See all 8,959 properties in Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mission Valley attractions

A bridge at night with its lights reflecting on the water.

Hotel Circle

8.2/10 (6,358 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.
See properties
A large stadium with a parking structure, surrounded by hills and a highway.

Snapdragon Stadium

8.4/10 (243 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Fashion Valley Mall

9.0/10 (111 reviews)
You can search for that perfect souvenir at Fashion Valley Mall during your stay in San Diego. Take in the fascinating museums and beautiful sunsets in this walkable area.
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Mission Valley Mall

8.8/10 (53 reviews)
You can do some window-shopping at Mission Valley Mall during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Town and Country San Diego

Learn about the events happening at Town and Country San Diego during your trip to San Diego. Wander the beautiful beaches and seaside in this family-friendly area.
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SDSU Mission Valley

Explore the campus of SDSU Mission Valley as part of your travels around San Diego. Check out the shops and top-notch restaurants in this family-friendly area.
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Legacy International Center

Enjoy an outing to Legacy International Center during your stay in San Diego. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.
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Things to do

San Diego Padres Baseball Game at Petco Park

San Diego Padres Baseball Game at Petco Park

$118
per adult
San Diego Padres Baseball Game at Petco Park
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

$11
per adult
San Diego: Luggage Storage in Marina
See all activities in San Diego

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.