Mission Valley Vacations from $343
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Mission Valley Vacation
With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.
The Latest Mission Valley Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Riviera Oaks Resort
San Diego Country Estates
Save 100% on your flight
Price was $563, price is now $343 per person
$343
per person
May 30 - Jun 4
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.6/10 Exceptional! (1,000 reviews)
Beautiful place and area. Would definitely stay again!!!
Reviewed on Apr 19, 2026
Los Bungalows
Save 100% on your flight
Price was $990, price is now $552 per person
$552
per person
May 30 - Jun 4
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (525 reviews)
Está ubicado en un lugar paradisíaco. La cama muy cómoda y todo muy limpio. Muchos lugares para divertirse y un apto muy romántico
Reviewed on Mar 23, 2026
Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Save 100% on your flight
Price was $848, price is now $524 per person
$524
per person
Jul 3 - Jul 6
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.4/10 Very Good! (1,753 reviews)
Clean room, a lot to do, beautiful place
Reviewed on Apr 28, 2026
City24 Hotel Little Italy Mission Hills
Middletown
Save 100% on your flight
Price was $1,261, price is now $800 per person
$800
per person
Jun 11 - Jun 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.6/10 Exceptional! (139 reviews)
Beautiful fully appointed rooms and excellent location.
Reviewed on Apr 29, 2026
Urban Boutique Hotel
Downtown San Diego
Save 100% on your flight
Price was $1,148, price is now $744 per person
$744
per person
Jul 24 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (1,283 reviews)
Location location location!!!
Reviewed on Apr 24, 2026
Where to stay in Mission Valley
Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
Downtown San Diego
4 out of top 10 points of interest in this area
4.5/5(8,598 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Mission Valley Hotel Deals
Handlery Hotel
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $137 total per night from May 12 to May 13
$137 total
May 12 - May 13
Total with taxes and fees
8.4/10 Very Good! (2,476 reviews)
I don’t like it
Reviewed on Apr 29, 2026
Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $94 total per night from May 3 to May 4
$94 total
May 3 - May 4
Total with taxes and fees
7.8/10 Good! (3,433 reviews)
That’s good
Reviewed on Apr 30, 2026
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $133 total per night from May 10 to May 11
$133 total
May 10 - May 11
Total with taxes and fees
8/10 Very Good! (2,607 reviews)
Clean room and great customer service.
Reviewed on Apr 29, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mission Valley
Hotel Circle
4/5(1,419 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.
Snapdragon Stadium
4/5(189 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Fashion Valley Mall
4.5/5(84 reviews)
You can search for that perfect souvenir at Fashion Valley Mall during your stay in San Diego. Take in the fascinating museums and beautiful sunsets in this walkable area.
Things to do
Oceanside Whale and Dolphin Watching Adventures
$57
per adult
90% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
$71
per adult
86% of travellers recommend
Explore a world of travel with Expedia
- San Diego County Hotels
- San Diego Hotels
- Hotels near Hotel Circle
- Cheap Hotels in San Diego County
- Hotels near Hazard Center Station
- Condo Rentals in Hazard Center Station
- Hotels near Mission Valley Center Station
- Hotels near Mission Valley Mall
- Hotels near San Diego Zoo
- Houseboats in Rio Vista Station
- Hotels near Rio Vista Station
- Hostels in Rio Vista Station
- Hotels near Fashion Valley Mall
- Hotels near Downtown San Diego
- Hotels near Fashion Valley Transit Center Station
- Condo Rentals in Fashion Valley Transit Center Station
- Apartments in Fashion Valley Transit Center Station
- Hotels near University Heights
- Hotels near Riverwalk Golf Club
- Hotels near J.A. Cooley Museum
- Hotels near San Diego Intl.
- Hotels near Hillcrest
- Hotels near Birdland
- Hotels near Old Cactus Garden
- Beach Hotels in San Diego County
- Hotels near Old Town San Diego
- Hotels near Linda Vista
- Hotels near Snapdragon Stadium
- Destination Hotels in Hillcrest
- Historic Hotels in Hillcrest
- Hotels with an Indoor Pool in Hillcrest
- Extended Stay Hotels in Hillcrest
- Beach Hotels in Hillcrest
- Romantic Hotels in Hillcrest
- 5 Star Hotels in Hillcrest
- Cheap Hotels in Hillcrest
- Best Western Hotels in Hillcrest
- Resorts & Hotels with Spas in Hillcrest
- Wyndham Hotels in Hillcrest
- Hilton Hotels in Hillcrest
- Hotels with Bars in Hillcrest
- Hotels with Free Parking in Hillcrest
- Hotels with Hot Tubs in Hillcrest
- Gay friendly Hotels in Hillcrest
- 3 Star Hotels in Hillcrest
- Marriott Hotels & Resorts in Hillcrest
- Hotels with Restaurants in Hillcrest
- 4 Star Hotels in Hillcrest
- Extended Stay America Hotels in Hillcrest
- All-Inclusive Resorts in Hillcrest
- Boutique Hotels in Hillcrest
- La Quinta Inn & Suites Hotels in Hillcrest
- Non-Smoking Hotels in Hillcrest
- Hotels with Tennis Courts in Hillcrest
- Hotels with a Pool in Hillcrest
- Hotels with a Gym in Hillcrest
- Hotels with Air Conditioning in Hillcrest
- Hotels with Fireplaces in Hillcrest
- Motel 6 Hotels in Hillcrest
- Hotels near Fenton Parkway Station
- Hotels near Gaslamp Quarter
- Hotels near Mission Valley East
- Flights to San Diego
- Flights from San Francisco (SFO) to San Diego (SAN)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from Phoenix (PHX) to San Diego (SAN)
- Flights from New York (JFK) to San Diego (SAN)
- Flights from Las Vegas (LAS) to San Diego (SAN)
- Flights from Chicago (ORD) to San Diego (SAN)
- Flights from Dallas (DFW) to San Diego (SAN)
- Flights from San Jose (SJC) to San Diego (SAN)
- Flights from Los Angeles (LAX) to San Diego (SAN)
- Flights from Denver (DEN) to San Diego (SAN)
- Flights from San Diego Intl.
- Flights from Portland (PDX) to San Diego (SAN)
- Flights from Boston (BOS) to San Diego (SAN)
- Flights from Sacramento (SMF) to San Diego (SAN)
- Flights from Houston (IAH) to San Diego (SAN)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.