Mission Valley Vacations from $447

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Your Mission Valley Vacation

With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.

The Latest Mission Valley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Los Bungalows

Los Bungalows

Save 100% on your flight
$447
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (553 reviews)
The Sofia Hotel

The Sofia Hotel

Downtown San Diego
$758
per person
Nov 11 - Nov 15
found 1 hour ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
8.6/10 Excellent! (2,586 reviews)
Pantai Inn

Pantai Inn

Village of La Jolla
Save 100% on your flight
$883
per person
Nov 21 - Nov 26
just found
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.4/10 Exceptional! (1,005 reviews)
Fun outside bar at night and the breakfast hits the spot

Reviewed on Sep 6, 2026

Guesthouse Hotel at La Valle

Guesthouse Hotel at La Valle

Save 100% on your flight
$544
per person
Oct 17 - Oct 21
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (219 reviews)
The location was fantastic. Very clean but not a lot of amenities. The best part of the experience was the staff. All were very friendly and responsive, we would go back in a heart beat.

Reviewed on Sep 9, 2026

Ocean Villas of Carlsbad

Ocean Villas of Carlsbad

Carlsbad Village
Save 100% on your flight
$1,274
per person
Oct 25 - Oct 30
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
9/10 Wonderful! (23 reviews)

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

3 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

A pier extending into calm waters with people on it and a sandy beach with seaweed and a few individuals.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

A lively street scene with outdoor seating at various bars and restaurants, including 'The Field' and 'Sloppy Joe's'.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

A sandy beach with a lifeguard tower, ocean waves, and people in the distance.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

A beach with palm trees, people, and buildings in the background.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Mission Valley Hotel Deals

Handlery Hotel

Handlery Hotel

950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
$136 total
Oct 5 - Oct 6
Total with taxes and fees
8.4/10 Very Good! (2,912 reviews)
"I’ve disliked quite a few hotels around this area of SD, but this was my first overwhelmingly positive experience at a hotel in SD!! Everything was perfect; the staff, the room, the amenities, and location were all amazing! I will definitely be coming back next time :)"

Reviewed on Sep 9, 2026

Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
$97 total
Sep 13 - Sep 14
Total with taxes and fees
Best Western Seven Seas
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$84 nightly
$97 total
Sep 28 - Sep 29
Total with taxes and fees
Days Inn by Wyndham San Diego Hotel Circle
See all 9,023 properties in Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mission Valley attractions

A bridge at night with its lights reflecting on the water.

Hotel Circle

8.2/10 (6,358 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.
See properties
A large stadium with a parking structure, surrounded by hills and a highway.

Snapdragon Stadium

8.4/10 (243 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Fashion Valley Mall

9.0/10 (111 reviews)
You can search for that perfect souvenir at Fashion Valley Mall during your stay in San Diego. Take in the fascinating museums and beautiful sunsets in this walkable area.
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Mission Valley Mall

8.8/10 (53 reviews)
You can do some window-shopping at Mission Valley Mall during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Town and Country San Diego

Learn about the events happening at Town and Country San Diego during your trip to San Diego. Wander the beautiful beaches and seaside in this family-friendly area.
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SDSU Mission Valley

Explore the campus of SDSU Mission Valley as part of your travels around San Diego. Check out the shops and top-notch restaurants in this family-friendly area.
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Legacy International Center

Enjoy an outing to Legacy International Center during your stay in San Diego. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.
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Things to do

San Diego Afternoon Sail

Spectacular Afternoon Sail on San Diego Bay

$21
per adult
Spectacular Afternoon Sail on San Diego Bay
Oceanside Whale and Dolphin Watching Adventures

Oceanside Whale and Dolphin Watching Adventures

$57
per adult
90% of travellers recommend
Oceanside Whale and Dolphin Watching Adventures
See all activities in San Diego

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.