Mission Valley Vacations from $319

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Your Mission Valley Vacation

With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.

The Latest Mission Valley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
San Diego Country Estates

San Diego Country Estates

San Diego Country Estates
Save 100% on your flight
$319
per person
Dec 10 - Dec 13
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.4/10 Exceptional! (303 reviews)
Pantai Inn

Pantai Inn

Village of La Jolla
Save 100% on your flight
$1,590
per person
Dec 1 - Dec 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
9.4/10 Exceptional! (1,008 reviews)
The Sofia Hotel

The Sofia Hotel

Downtown San Diego
$1,161
per person
Nov 24 - Nov 29
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Diego (SAN)
8.6/10 Excellent! (2,695 reviews)
Guesthouse Hotel at La Valle

Guesthouse Hotel at La Valle

Save 100% on your flight
$504
per person
Jan 15 - Jan 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (252 reviews)
Coronado Beach Resort

Coronado Beach Resort

Historic Downtown Coronado
Save 100% on your flight
$469
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (825 reviews)
This was a convenient hotel change from the Loews resort as they have some sort of arrangement with each other and a shuttle that runs between the locations. I would recommend asking for a room that faces away from the street though as that can be quite noisy. I loved the location for it's walkability, safety, access to nice beaches and restaurants.

Reviewed on Oct 20, 2026

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

3 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

A pier extending into calm waters with people on it and a sandy beach with seaweed and a few individuals.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

A lively street scene with outdoor seating at various bars and restaurants, including 'The Field' and 'Sloppy Joe's'.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

A sandy beach with a lifeguard tower, ocean waves, and people in the distance.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

1 out of top 10 points of interest in this area

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Mission Valley Hotel Deals

Handlery Hotel

Handlery Hotel

950 Hotel Cir N San Diego CA
$111 nightly
$128 total
Nov 16 - Nov 17
Total with taxes and fees
Handlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$88 nightly
$102 total
Nov 3 - Nov 4
Total with taxes and fees
8/10 Very Good! (3,141 reviews)
"Great stay. Thank you the staff."

Reviewed on Oct 21, 2026

Days Inn by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
$97 total
Oct 22 - Oct 23
Total with taxes and fees
Best Western Seven Seas
See all 9,070 properties in Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mission Valley attractions

A bridge at night with its lights reflecting on the water.

Hotel Circle

8.2/10 (6,358 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.
See properties
A large stadium with a parking structure, surrounded by hills and a highway.

Snapdragon Stadium

8.4/10 (243 reviews)
Catch an event at Snapdragon Stadium during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Fashion Valley Mall

9.0/10 (111 reviews)
You can search for that perfect souvenir at Fashion Valley Mall during your stay in San Diego. Take in the fascinating museums and beautiful sunsets in this walkable area.
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Mission Valley Mall

8.8/10 (53 reviews)
You can do some window-shopping at Mission Valley Mall during your trip to San Diego. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Town and Country San Diego

Learn about the events happening at Town and Country San Diego during your trip to San Diego. Wander the beautiful beaches and seaside in this family-friendly area.
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SDSU Mission Valley

Explore the campus of SDSU Mission Valley as part of your travels around San Diego. Check out the shops and top-notch restaurants in this family-friendly area.
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Legacy International Center

Enjoy an outing to Legacy International Center during your stay in San Diego. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.
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Things to do

San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

$71
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

$11
per adult
San Diego: Luggage Storage in Marina
See all activities in San Diego

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.