A white colonial-style building with a bell tower, surrounded by cacti and flowering plants.

Mission Valley Vacations from $362

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Your Mission Valley Vacation

With a vacation package to Mission Valley, you can spend less time planning and more time experiencing this interesting neighborhood. From its shopping to its dining, there's so much to discover here. Can't wait to do some sightseeing during your trip to Mission Valley? Don't miss nearby attractions like San Diego Zoo, Balboa Park and University of San Diego. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Mission Valley, Expedia will help get you there.

The Latest Mission Valley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • An outdoor seating area with tables and chairs, surrounded by a brick building with a glass entrance.
    Jan 29 - Feb 1

    The Sofia Hotel + Flight

    Downtown San Diego
    3 nights
    3.5 star property
    8.8/10 - Excellent (2,784 reviews)
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    $658
    $328
    per traveler
    found 1 day ago
    The Sofia Hotel
  • A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
    Feb 1 - Feb 6

    Legacy Resort Hotel & Spa + Flight

    Mission Valley
    5 nights
    4.0 star property
    9.2/10 - Wonderful (3,101 reviews)
    "Hotel was very well appointed. Staff was friendly, central location to everything in San Diego"
    Reviewed November 14, 2026
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    $881
    $481
    per traveler
    found 1 day ago
    Legacy Resort Hotel & Spa
  • A balcony with wicker furniture, a stone building, and a view of the ocean and golf course.
    Dec 21 - Dec 26

    Pantai Inn + Flight

    Village of La Jolla
    5 nights
    3.5 star property
    9.4/10 - Exceptional (1,000 reviews)
    Roundtrip • New York (EWR) - San Diego (SAN)
    EWR - SAN • 1 stop SAN - EWR • Nonstop
    $2,407
    $1,450
    per traveler
    found 10 hours ago
    Pantai Inn
  • A hotel room with two beds, a large mirror, a wooden headboard, and a carpeted floor.
    Jan 15 - Jan 18

    Hotel Z + Flight

    Downtown San Diego
    3 nights
    3.0 star property
    9.2/10 - Wonderful (1,231 reviews)
    "We got charged a extra $100 dollars for being out of state. Building was being renovated while we stayed"
    Reviewed November 15, 2026
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    Save 100% on your flight
    $586
    $362
    per traveler
    found 9 hours ago
    Hotel Z
  • A spacious lobby with a central wooden table, potted plants, and a large blue sculpture.
    Jan 29 - Feb 1

    Margaritaville Hotel San Diego Gaslamp Quarter + Flight

    Downtown San Diego
    3 nights
    4.0 star property
    9.0/10 - Wonderful (1,598 reviews)
    "The room was very clean and daily service was much appreciated. The only complaint we had was the lighting in our bedroom room and bathroom were minimal."
    Reviewed November 14, 2026
    Roundtrip • Denver (DEN) - San Diego (SAN)
    DEN - SAN • Nonstop SAN - DEN • Nonstop
    $712
    $442
    per traveler
    found 1 day ago
    Margaritaville Hotel San Diego Gaslamp Quarter

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
Learn more about Mission Valley
A large stadium with the sign "Cobo Park" and palm trees around it.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

A pier extending into the ocean with buildings at the end, under a partly cloudy sky.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

A coastal cityscape with a long sandy beach, a pier, and dense urban buildings.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Discover the most popular places to visit in Mission Valley

A bridge at night with its lights reflecting on the water.

Hotel Circle

8.2/10 (6,358 reviews)
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.
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What to do near Mission Valley

LEGOLAND® California Resort

LEGOLAND® California Tickets

$91
per adult
84% of travelers recommend
LEGOLAND® California Tickets
See all activities near Mission Valley

Mission Valley Hotel Deals

An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.2 out of 10, Very good, (2,740 reviews)
$122 nightly
The price is $140
Nov 22 - Nov 23
Total with taxes and fees
Hilton San Diego Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Mission Valley
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.