Panacea Vacation Rentals

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Check prices for these dates

In two weeks
Apr 24 - Apr 26
In two months
Jun 5 - Jun 7
In three months
Jul 3 - Jul 5
In four months
Jul 31 - Aug 2

Our top choices for Panacea vacation rentals

Outdoor dining

Fisherman's Retreat Entire home in Panacea, Florida

Fisherman's Retreat Entire home in Panacea, Florida
Panacea
$256 nightly
The price is $282
Apr 12 - Apr 13
Total with taxes and fees
Fisherman's Retreat Entire home in Panacea, Florida
Beach nearby, sun loungers

Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!

Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!
Panacea
10.0 out of 10, Exceptional, (247 reviews)
"2nd time staying here and it was so beautiful we will definitely be back, everything was wonderful and the host was amazing."
United States
Carrie J.
$364 nightly
The price is $397
Apr 26 - Apr 27
Total with taxes and fees
Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!
TV

romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
$278 nightly
The price is $306
Apr 14 - Apr 15
Total with taxes and fees
romantic get away for 2 right on the Ochlockonee river
Exterior

Coastal Cottage- a nature lover's paradise!

Coastal Cottage- a nature lover's paradise!
Panacea
10.0 out of 10, Exceptional, (1 review)
"This place is amazing. It is the cleanest cutest cottage we have stayed in throughout all of Florida. Monica was an excellent host and set us up. Praise Jesus for that! You can walk to two restaurants which are next door. It is hard to find places to stay with my wife having miold illness, especially in Florida, but this has the cleanest, clearest air . We are able to stay with confidence that it is clean. Views of the sunrise on the bay are excellent. We brought our boat to fish and enjoyed...
United States
Lonnie L N.
$443 nightly
The price is $464
Apr 24 - Apr 25
Total with taxes and fees
Coastal Cottage- a nature lover's paradise!
Property grounds

09) Queen Kitchenette by the Bay

09) Queen Kitchenette by the Bay
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
09) Queen Kitchenette by the Bay
Property grounds

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
Panacea
9.8 out of 10, Exceptional, (96 reviews)
"We really enjoyed our time at Skipper! It's location on the west end of Alligator Point is perfect for walking the beach for miles in either direction. With so many shells to search for and so many dolphins to watch, our time there was so relaxing that we can't wait to go back!"
United States
Karen R.
$437 nightly
The price is $477
Apr 23 - Apr 24
Total with taxes and fees
Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
Interior

Bill's Bay Breeze- relax on the porch and enjoy the view!

Bill's Bay Breeze- relax on the porch and enjoy the view!
Alligator Point
9.4 out of 10, Exceptional, (9 reviews)
"Great location"
New Zealand
Lee Ann K.
$497 nightly
The price is $519
Apr 14 - Apr 15
Total with taxes and fees
Bill's Bay Breeze- relax on the porch and enjoy the view!
Interior

Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
United States
Scott A.
$422 nightly
The price is $461
Apr 13 - Apr 14
Total with taxes and fees
Point & Paddle Waterfront Retreat @Alligator Point
Property grounds

Queen Kitchenette by the Bay #15

Queen Kitchenette by the Bay #15
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Queen Kitchenette by the Bay #15
Property grounds

Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Cozy Panacea Retreat #3 (King)
Property grounds

Queen Kitchenette by the Bay #14

Queen Kitchenette by the Bay #14
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Queen Kitchenette by the Bay #14
Property grounds

Queen Kitchenette by the Bay #16

Queen Kitchenette by the Bay #16
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Queen Kitchenette by the Bay #16
Property grounds

Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Cozy Panacea Retreat #7 (King)
Property grounds

Queen Kitchenette by the Bay #10

Queen Kitchenette by the Bay #10
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Queen Kitchenette by the Bay #10
Property grounds

Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Queen Kitchenette by the Bay #13
Beach

Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
$162 nightly
The price is $177
Apr 13 - Apr 14
Total with taxes and fees
Cozy Panacea Retreat #3 (King)
On the beach

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Alligator Point
10.0 out of 10, Exceptional, (124 reviews)
"Love this house! Plenty of beds, great views and the house was stocked as well as I’ve ever seen in a rental property (I’m serious!!!). Thank you!"
United States
Scott G.
$2,028 nightly
The price is $2,214
Apr 12 - Apr 13
Total with taxes and fees
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Property grounds

Perfect Panacea 1 Bedroom Apt, #2

Perfect Panacea 1 Bedroom Apt, #2
Panacea
$162 nightly
The price is $177
Apr 12 - Apr 13
Total with taxes and fees
Perfect Panacea 1 Bedroom Apt, #2
Property grounds

Queen Kitchenette by the Bay #17

Queen Kitchenette by the Bay #17
Panacea
$173 nightly
The price is $190
Apr 12 - Apr 13
Total with taxes and fees
Queen Kitchenette by the Bay #17
On the beach, sun loungers

Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!

Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!
Alligator Point
9.8 out of 10, Exceptional, (119 reviews)
"Great!"
United States
Madeline Y.
$571 nightly
The price is $624
May 10 - May 11
Total with taxes and fees
Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent
"Everything about ours stay was absolutely amazing! We had a group of four, one being in a wheelchair. The house was completely accessible to her except for the bathtub. However she could get in there and we used a shower chair. She was even able to put her feet in the water at the beach. The cottage is absolutely amazing. It was so clean when we got there, we spilled a little juice on the floor and when I wiped it up no dirt come up with the paper towel, not even a little. The house was fully stocked with everything we needed. It had paper towels, toilet paper, towels, washcloth, beach towels, Beach blankets, it was fully stocked of everything. However we did use most of our own things, but it was there if we needed it. It was super quiet and peaceful, not a lot of traffic on the road. The only thing I would add, is that there needs to be a warning on the driveway dip. We were driving a wheelchair accessible van and bottomed out not knowing that the dip was right as you're pulling in driveway. Other than the little mishap with the driveway, my group had an amazing time and I would highly recommend this place if you're planning on visiting Panacea!"
Leslea S. 14-night trip
Posted 11 hours ago
Hideaway Beach Cottage on waterfront with amazing views.

Find out more about Panacea

Everything you need to know about Panacea vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panacea vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panacea in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $397 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panacea?

Yes, there are vacation rentals in Panacea close to Gulf Specimen Public Aquarum, or you can go with a secluded option if you'd like a relaxing place to stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best vacation rentals in Panacea?

Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis: Visitors give good reviews to this Panacea vacation home rental, which is located by the ocean and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a selection of games and a hot tub. Some other homes for rent in Panacea include 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch and Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs..

How many vacation rentals are there in Panacea?

Choose from 170 Expedia vacation rentals in Panacea for a memorable vacation.

What’s there to see and do in Panacea?

Mashes Sand Beach and Wilson Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Alligator Point Beach and Bald Point State Park are other places worth a visit.

What’s a vacation rental in Panacea like?

Vacation rentals are privately owned properties where you can stay for a few weeks or just a few days in Panacea. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.