A pier extending into calm waters with a small boat docked at the end.

Panacea Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Sep 4 - Sep 6
In two months
Oct 16 - Oct 18
In three months
Nov 13 - Nov 15
In four months
Dec 11 - Dec 13

Our top choices for Panacea vacation rentals

Smart TV

1. Panacea Treehouse⭐️ Waterfront-Boat Friendly

Panacea Treehouse⭐️ Waterfront-Boat Friendly
Panacea
10.0 out of 10, Exceptional, (25 reviews)
"Great place to stay while fishing"
United States
Benjamin S.
$286 nightly
The price is $315
Aug 23 - Aug 24
Total with taxes and fees
Panacea Treehouse⭐️ Waterfront-Boat Friendly
Beach

2. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
$162 nightly
The price is $178
Aug 23 - Aug 24
Total with taxes and fees
Cozy Panacea Retreat #3 (King)
TV

3. romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
$287 nightly
The price is $315
Aug 23 - Aug 24
Total with taxes and fees
romantic get away for 2 right on the Ochlockonee river
Marina

4. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks
Panacea
10.0 out of 10, Exceptional, (4 reviews)
"Had a great stay! We would book here again."
United States
Ashley D.
$430 nightly
The price is $473
Aug 26 - Aug 27
Total with taxes and fees
Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks
Interior

5. Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
United States
Scott A.
$446 nightly
The price is $487
Aug 23 - Aug 24
Total with taxes and fees
Point & Paddle Waterfront Retreat @Alligator Point
Outdoor dining

6. The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida
Panacea
10.0 out of 10, Exceptional, (99 reviews)
"Excellent beach front location, wonderful amenities like beach chairs, umbrellas, toys and towels made the stay easy and stress free! "
United States
Juliet H.
$589 nightly
The price is $644
Aug 31 - Sep 1
Total with taxes and fees
The Best Beach-Front House “Get-A-Way” in Florida
Property grounds

7. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
Panacea
9.6 out of 10, Exceptional, (93 reviews)
"We were traveling with 1 small dog, a 1 year old and 8 adults for 1 daughter graduation from FSU. The host confirmed the people coming and when we got there she had a cute little doggie set up ready and a high chair for our granddaughter. The property was perfect, the view was extraordinary. We are thrilled and will be back! It was an easy 1 hour drive from FSU to the house and we were so happy with everything about it!"
United States
Stacy C.
$621 nightly
The price is $678
Aug 24 - Aug 25
Total with taxes and fees
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
Property grounds

8. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
$162 nightly
The price is $178
Aug 25 - Aug 26
Total with taxes and fees
Cozy Panacea Retreat #3 (King)
Property grounds

9. Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
$162 nightly
The price is $178
Aug 25 - Aug 26
Total with taxes and fees
Queen Kitchenette by the Bay #13
Exterior

10. NEW - St. Teresa Beach Escape w/ Private Beach Acc

NEW - St. Teresa Beach Escape w/ Private Beach Acc
Lanark Village
10.0 out of 10, Exceptional, (2 reviews)
"This house was very comfortable, beds, pillows, towels, sofa, etc. Quiet, peaceful, serene setting. Close proximity to beach and the pool was an added bonus!Thank you for a very enjoyable stay!"
United States
Debra M.
$699 nightly
The price is $766
Aug 23 - Aug 24
Total with taxes and fees
NEW - St. Teresa Beach Escape w/ Private Beach Acc
Property grounds

11. Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
$162 nightly
The price is $178
Sep 13 - Sep 14
Total with taxes and fees
Cozy Panacea Retreat #7 (King)
Property grounds

12. Perfect Panacea 1 Bedroom Apt, #2

Perfect Panacea 1 Bedroom Apt, #2
Panacea
$162 nightly
The price is $178
Sep 13 - Sep 14
Total with taxes and fees
Perfect Panacea 1 Bedroom Apt, #2
Property grounds

13. Queen Kitchenette by the Bay #8

Queen Kitchenette by the Bay #8
Panacea
$201 nightly
The price is $221
Aug 23 - Aug 24
Total with taxes and fees
Queen Kitchenette by the Bay #8
1 bedroom, internet, bed sheets

14. Panacea Cozy Retreat #6 (DQ)

Panacea Cozy Retreat #6 (DQ)
Panacea
$202 nightly
The price is $222
Aug 23 - Aug 24
Total with taxes and fees
Panacea Cozy Retreat #6 (DQ)
1 bedroom, desk, WiFi, bed sheets

15. Panacea Cozy Retreat #4 (DQ)

Panacea Cozy Retreat #4 (DQ)
Panacea
$202 nightly
The price is $222
Aug 23 - Aug 24
Total with taxes and fees
Panacea Cozy Retreat #4 (DQ)
On the beach

16. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Alligator Point
10.0 out of 10, Exceptional, (131 reviews)
"Beautiful house with awesome views of the gulf and the bay from all rooms. Fenced in yard was perfect for our dog. Location is very relaxing. I can't wait to go back."
United States
V G.
$2,015 nightly
The price is $2,204
Aug 23 - Aug 24
Total with taxes and fees
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Outdoor dining

17. Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf

Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf
Crawfordville
10.0 out of 10, Exceptional, (81 reviews)
"What a great property! The house is fully equipped for your stay and the sunrises are breathtaking!"
United States
Donna M.
$282 nightly
The price is $310
Aug 23 - Aug 24
Total with taxes and fees
Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf
Coffee/tea maker, fridge, microwave, oven

18. Enjoy Crawfordville at the Courtyard’s Pelican Cottage.

Enjoy Crawfordville at the Courtyard’s Pelican Cottage.
Crawfordville
10.0 out of 10, Exceptional, (138 reviews)
"Super cute cottage, roomy and equipped with everything you would need for your stay. I enjoyed a cup of hot tea on the front porch on the day it rained. Lots of great restaurants nearby. Owner was very helpful and answered our questions right away. Hope to come back soon!"
United States
Jennifer W.
$198 nightly
The price is $218
Sep 20 - Sep 21
Total with taxes and fees
Enjoy Crawfordville at the Courtyard’s Pelican Cottage.
Property grounds

19. Enjoy Crawfordville at the Courtyard’s Oyster Cottage

Enjoy Crawfordville at the Courtyard’s Oyster Cottage
Crawfordville
10.0 out of 10, Exceptional, (69 reviews)
"Wonderful stay, everything clean and comfortable."
United States
Robert G.
$209 nightly
The price is $230
Sep 2 - Sep 3
Total with taxes and fees
Enjoy Crawfordville at the Courtyard’s Oyster Cottage
Beach

20. Dragonfly on the Canal Golf cart included!

Dragonfly on the Canal Golf cart included!
Crawfordville
10.0 out of 10, Exceptional, (54 reviews)
"Was a great spacious place. We stayed for graduation weekend and could not have been happier. The porch is amazing!"
United States
Kristy B.
$334 nightly
The price is $367
Aug 23 - Aug 24
Total with taxes and fees
Dragonfly on the Canal Golf cart included!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Panacea Hotel Reviews

Hideaway Beach Cottage on waterfront with amazing views.

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent
"Incredible experience all the way around !Clean, cozy, inviting and stellar communication!!"
Cherie D. 10-night trip
Posted 1 day ago
Hideaway Beach Cottage on waterfront with amazing views.

Find out more about Panacea

Everything you need to know about Panacea vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panacea vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panacea in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $315 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panacea?

Yes, there are vacation rentals in Panacea close to Gulf Specimen Public Aquarum, or you can go with a secluded option if you'd like a relaxing place to stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best vacation rentals in Panacea?

Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations: Visitors give good reviews to this Panacea vacation home rental, which is located on the beach and has a patio, a barbecue grill, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Another good choice for your trip to Panacea is Best deal at Alligator Point.

How many vacation rentals are there in Panacea?

Choose from 179 Expedia vacation rentals in Panacea for a memorable vacation.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Wilson Beach are other places worth a visit.

What’s a vacation rental in Panacea like?

Vacation rentals are privately owned properties where you can stay for a few weeks or just a few days in Panacea. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.