Panacea Vacation Rentals from $300: Search Short-Term Rentals

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Panacea vacation rentals

A wooden bench in a natural setting with a lake and trees in the background.

1. Queen Kitchenette by the Bay #13

Panacea

$155 nightly

Nov 16 - Nov 17

Total with taxes and fees

A two-story house with a balcony, a covered porch, and a wooden deck.

2. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

Panacea

Benjamin S.

$271 nightly

Nov 16 - Nov 17

Total with taxes and fees

A deck with a metal lamp, overlooking a calm lake and a pier extending into the water.

3. romantic get away for 2 right on the Ochlockonee river

Panacea

Laurie K.

$272 nightly

Nov 16 - Nov 17

Total with taxes and fees

A beach with footprints and sparse vegetation, leading to calm water under a clear sky.

4. Tiny Tides Waterfront Cottage

Panacea

Jason W.

$341 nightly

Nov 20 - Nov 21

Total with taxes and fees

5. 09) Queen Kitchenette by the Bay

Panacea

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

6. Perfect Panacea 1 Bedroom Apt, #2

Panacea

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

A tree silhouetted against a sunset sky, a body of water, and a snowy landscape.

7. Cozy Panacea Retreat #3 (King)

Panacea

Faith V.

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

A wooden pier extending into calm blue waters, leading to a sandy beach with sparse vegetation.

8. Private beach winter escape on the bay with fishing and kayaks

Panacea

Ashley D.

$418 nightly

Nov 16 - Nov 17

Total with taxes and fees

A kayak with a red and orange design, resting on grass next to a green kayak.

9. Queen Kitchenette by the Bay #16

Panacea

$155 nightly

Nov 16 - Nov 17

Total with taxes and fees

10. Cozy Panacea Retreat #3 (King)

Panacea

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

11. Queen Kitchenette by the Bay #10

Panacea

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

12. Queen Kitchenette by the Bay #15

Panacea

$155 nightly

Nov 16 - Nov 17

Total with taxes and fees

13. Queen Kitchenette by the Bay #11

Panacea

$155 nightly

Nov 16 - Nov 17

Total with taxes and fees

14. Queen Kitchenette by the Bay #14

Panacea

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

15. Cozy Panacea Retreat #7 (King)

Panacea

$154 nightly

Nov 16 - Nov 17

Total with taxes and fees

A beach with sand, grass, and the ocean.

16. Point & Paddle Waterfront Retreat @Alligator Point

Alligator Point

Scott A.

$424 nightly

Nov 16 - Nov 17

Total with taxes and fees

17. Queen Kitchenette by the Bay #8

Panacea

$191 nightly

Nov 16 - Nov 17

Total with taxes and fees

A wooden deck with wicker chairs and a long table, overlooking a beach and ocean.

18. The Best Beach-Front House “Get-A-Way” in Florida

Panacea

Lisa R.

$583 nightly

Nov 16 - Nov 17

Total with taxes and fees

Two twin beds with matching headboards, a nightstand with a lamp, a framed picture on the wall, and an American flag.

19. Panacea Cozy Retreat #4 (DQ)

Panacea

$192 nightly

Nov 16 - Nov 17

Total with taxes and fees

20. Panacea Cozy Retreat #6 (DQ)

Panacea

$192 nightly

Nov 16 - Nov 17

Total with taxes and fees

View all properties

Find vacation rentals that suit your style

Private vacation homes

Cabins

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top Panacea Hotel Reviews

Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes, Tennis, 🐶 friendly

10/10 Excellent

"We ran into a few issues at check-in (not anybody’s fault), and Heather was more than accommodating in providing swift remedy. The property was very pleasant and clean, and we couldn’t have been more pleased with the overall experience."

Lighthouse- enjoy the water, bask in the view

10/10 Excellent

"Everything you might need is at this beach house. Toys and beach chairs, ample towels and well stocked kitchen.Both sunrise and sunset were spectacular and plenty of shells to be had.The only thing missing was comfortable chairs in the living room. The barrel chairs looked great but a high back chair with footstool or recliner would make it perfect."

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

10/10 Excellent

"We had an excellent stay the first week of November. The house was extremely clean and stocked very well. When I mean stocked I mean it had shampoo, conditioner, soap, toilet paper, lotion, Q-tips, dental floss, makeup remover pads in the bathrooms. The laundry room had everything you need to do laundry, laundry detergent and softener that lasted us the whole week. The kitchen had dishwashing soap, dishwasher soap, all of the necessary appliances. When we arrived, there was a bottle of wine waiting for us. The views of the ocean were outstanding and we enjoyed the golf cart rides to see nature. We’ve never seen a white squirrel before until we visited Bald Point State Park. Our first night we had four Whitetail deer in our backyard. Once the sun came out and the weather warmed up. We were able to enjoy the paddleboard in the ocean with the dolphins! We were lucky to meet the owner while out riding in the gulf cart! Very nice man! My husband enjoyed playing gulf at the Wakulla Sand Gulf club. This house has a shed full of toys: 4 bikes, beach chairs and beach toys, life jackets for kayaking in the ocean, and a fire pit for roast marshmallows! There is no need to leave the house once you get here!"

BEACH FRONT gathering spot for family, friends and pups. WINTER RATES AVAILABLE!

10/10 Excellent

"This is a fantastic rental on the beach, with an amazing outdoor area made for relaxing. This is the second time I’ve stayed here and I’m sure it will not be the last. I’ve had consistently great experiences with check in, communication, etc."

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"If you are thinking of booking this home I would definitely recommend it. IF you have never been to the "forgotten coast" of Florida it is an experience like no other. You have the beautiful weather and scenery and water but without any of the traffic. there was literally no one in town or on any of the roads. We went to the beach and we were the only people on the beach, it was like our own private beach. The home is very cozy and has everything you need. You are not going to spend much time inside anyway. I contacted the host Agnes the day before checking in and she responded within 2 minutes. We had no problems at all and everything in the home is as the pictures represent. The view on the river is amazing and there are many great places to go. If you are looking to get away and have total relaxation this is the place to go. IF you are looking to go out to do more tourist type things like mini golf, restuarants, and so on then this is not your place to visit. We took this vacation to get a rest from running our business. It was several days of total paradise and peace. If you are looking for the most peaceful relaxing vacation ever then book this place."

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

10/10 Excellent

"Overall everything was excellent, clean rooms and beds, communication with host Nick, beach view plus being so close to beach, the screened porch was the favorite hang out for all of us during day and night. A few things to note: Kitchen utensils and stove could have used a really good cleaning so We chose to eat out instead the whole time. We also had to purchase more trash bags, paper towels and toilet paper not enough was supplied for our 7 days for 7 adults. Would come back again but next time would bring own cookware, grill, paper plates and plastic utensils. Lovely Beachfront house! Sunrises and Sunsets are amazing!! Quiet and away from the busy city if that’s what you like."

Find out more about Panacea

Everything you need to know about Panacea vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panacea vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panacea in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $300 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Things to do in Tallahassee

Frequently asked questions

Can I find vacation rentals in Panacea?

Yes, there are vacation rentals in Panacea close to Gulf Specimen Public Aquarum, or you can go with a secluded option if you'd like a relaxing place to stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best vacation rentals in Panacea?

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.: Visitors give good reviews to this Panacea vacation home rental, which is located on the beach and has an outdoor pool, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. Some other homes for rent in Panacea include Your Fall Escape: FSU Football & Scalloping and Coastal Getaway on canal-steps to the beach.

How many vacation rentals are there in Panacea?

Choose from 177 Expedia vacation rentals in Panacea for a memorable vacation.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Wilson Beach are other places worth a visit.

What’s a vacation rental in Panacea like?

Vacation rentals are privately owned properties where you can stay for a few weeks or just a few days in Panacea. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.

Panacea Vacation Rentals

Bundle & Save

OneKeyCash

Upfront pricing

Check prices for these dates

Our top choices for Panacea vacation rentals

1. Queen Kitchenette by the Bay #13

2. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

3. romantic get away for 2 right on the Ochlockonee river

4. Tiny Tides Waterfront Cottage

5. 09) Queen Kitchenette by the Bay

6. Perfect Panacea 1 Bedroom Apt, #2

7. Cozy Panacea Retreat #3 (King)

8. Private beach winter escape on the bay with fishing and kayaks

9. Queen Kitchenette by the Bay #16

10. Cozy Panacea Retreat #3 (King)

11. Queen Kitchenette by the Bay #10

12. Queen Kitchenette by the Bay #15

13. Queen Kitchenette by the Bay #11

14. Queen Kitchenette by the Bay #14

15. Cozy Panacea Retreat #7 (King)

16. Point & Paddle Waterfront Retreat @Alligator Point

17. Queen Kitchenette by the Bay #8

18. The Best Beach-Front House “Get-A-Way” in Florida

19. Panacea Cozy Retreat #4 (DQ)

20. Panacea Cozy Retreat #6 (DQ)

Find vacation rentals that suit your style

Top Panacea Hotel Reviews

Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes, Tennis, 🐶 friendly

Find out more about Panacea

Explore a world of travel with Expedia

Frequently asked questions

Expedia's Latest Trends

Go further with the Expedia app