A coastal resort with beachfront villas and a clear blue sky.

Panacea Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Panacea vacation rentals

A tree silhouetted against a sunset sky, a body of water, and a snowy landscape.

1. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
9.0 out of 10, Wonderful, (2 reviews)
"Great communication. Comfortable"
United States
Faith V.
$162 nightly
The price is $178
Oct 15 - Oct 16
Total with taxes and fees
Cozy Panacea Retreat #3 (King)
A cozy living room with a brown leather sofa, a dining table set with plates, and a view of the sea through large windows.

2. romantic get away for 2 right on the Ochlockonee river

romantic get away for 2 right on the Ochlockonee river
Panacea
6.0 out of 10, (2 reviews)
"Wonderful accommodations-clean and comfortable. "
United States
Laurie K.
$285 nightly
The price is $313
Oct 19 - Oct 20
Total with taxes and fees
romantic get away for 2 right on the Ochlockonee river
A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

3. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
Panacea
9.8 out of 10, Exceptional, (27 reviews)
"Great place to stay while fishing"
United States
Benjamin S.
$290 nightly
The price is $319
Oct 19 - Oct 20
Total with taxes and fees
Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
A covered outdoor area with a wooden deck, white furniture, and a view of the water.

4. Tiny Tides Waterfront Cottage

Tiny Tides Waterfront Cottage
Panacea
10.0 out of 10, Exceptional, (12 reviews)
"What a perfect escape! We thoroughly enjoyed our stay at Tiny Tides. The cozy, comfortable vibe, the peaceful location, and the easy access to everything made our trip truly special. We had a fantastic time and will definitely be back soon!"
United States
Jason W.
$350 nightly
The price is $386
Oct 15 - Oct 16
Total with taxes and fees
Tiny Tides Waterfront Cottage
A wooden bench in a natural setting with a lake and trees in the background.

5. Queen Kitchenette by the Bay #16

Queen Kitchenette by the Bay #16
Panacea
10.0 out of 10, Exceptional, (1 review)
$163 nightly
The price is $179
Oct 20 - Oct 21
Total with taxes and fees
Queen Kitchenette by the Bay #16
A dock extending into a body of water with a covered structure at the end.

6. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks
Panacea
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful view and beautiful home. Enjoyed making memories at this place"
United States
Toby H.
$436 nightly
The price is $481
Oct 15 - Oct 16
Total with taxes and fees
Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks
A wooden bench in a natural setting with a lake and trees in the background.

7. Queen Kitchenette by the Bay #15

Queen Kitchenette by the Bay #15
Panacea
$163 nightly
The price is $179
Oct 20 - Oct 21
Total with taxes and fees
Queen Kitchenette by the Bay #15
A wooden bench in a natural setting with a lake and trees in the background.

8. Queen Kitchenette by the Bay #14

Queen Kitchenette by the Bay #14
Panacea
$162 nightly
The price is $178
Oct 27 - Oct 28
Total with taxes and fees
Queen Kitchenette by the Bay #14
A wooden bench in a natural setting with a lake and trees in the background.

9. Perfect Panacea 1 Bedroom Apt, #2

Perfect Panacea 1 Bedroom Apt, #2
Panacea
$162 nightly
The price is $178
Oct 15 - Oct 16
Total with taxes and fees
Perfect Panacea 1 Bedroom Apt, #2
A wooden bench in a natural setting with a lake and trees in the background.

10. Cozy Panacea Retreat #3 (King)

Cozy Panacea Retreat #3 (King)
Panacea
$162 nightly
The price is $178
Oct 15 - Oct 16
Total with taxes and fees
Cozy Panacea Retreat #3 (King)
A wooden bench in a natural setting with a lake and trees in the background.

11. Cozy Panacea Retreat #7 (King)

Cozy Panacea Retreat #7 (King)
Panacea
$162 nightly
The price is $178
Oct 15 - Oct 16
Total with taxes and fees
Cozy Panacea Retreat #7 (King)
A wooden bench in a natural setting with a lake and trees in the background.

12. Queen Kitchenette by the Bay #13

Queen Kitchenette by the Bay #13
Panacea
$163 nightly
The price is $179
Oct 15 - Oct 16
Total with taxes and fees
Queen Kitchenette by the Bay #13
A wooden deck with wicker furniture, a small round table, and a view of the ocean.

13. Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
Panacea
9.6 out of 10, Exceptional, (107 reviews)
"This was our second visit to this house. We love it! It’s clean & well maintained. Close to the beach. Love the outdoor shower! We will definitely return."
United States
robin k.
$454 nightly
The price is $496
Oct 18 - Oct 19
Total with taxes and fees
Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
A wooden bench in a natural setting with a lake and trees in the background.

14. 09) Queen Kitchenette by the Bay

09) Queen Kitchenette by the Bay
Panacea
$162 nightly
The price is $178
Oct 15 - Oct 16
Total with taxes and fees
09) Queen Kitchenette by the Bay
A wooden bench in a natural setting with a lake and trees in the background.

15. Queen Kitchenette by the Bay #11

Queen Kitchenette by the Bay #11
Panacea
$163 nightly
The price is $179
Oct 15 - Oct 16
Total with taxes and fees
Queen Kitchenette by the Bay #11
A wooden bench in a natural setting with a lake and trees in the background.

16. Queen Kitchenette by the Bay #10

Queen Kitchenette by the Bay #10
Panacea
$162 nightly
The price is $178
Oct 15 - Oct 16
Total with taxes and fees
Queen Kitchenette by the Bay #10
A wooden deck with wicker chairs and a long table, overlooking a beach and ocean.

17. The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida
Panacea
10.0 out of 10, Exceptional, (100 reviews)
"This is our 4th time staying here and we still love it. Lots of good memories being made with my family in such a wonderful place. We'll be back next year! Thanks again!"
United States
Brad P.
$650 nightly
The price is $710
Oct 31 - Nov 1
Total with taxes and fees
The Best Beach-Front House “Get-A-Way” in Florida
A wooden bench in a natural setting with a lake and trees in the background.

18. Queen Kitchenette by the Bay #8

Queen Kitchenette by the Bay #8
Panacea
$200 nightly
The price is $220
Oct 21 - Oct 22
Total with taxes and fees
Queen Kitchenette by the Bay #8
A wooden bench in a natural setting with a lake and trees in the background.

19. Queen Kitchenette by the Bay #17

Queen Kitchenette by the Bay #17
Panacea
$214 nightly
The price is $235
Oct 20 - Oct 21
Total with taxes and fees
Queen Kitchenette by the Bay #17
Two twin beds with matching headboards, a nightstand with a lamp, a framed picture on the wall, and an American flag.

20. Panacea Cozy Retreat #4 (DQ)

Panacea Cozy Retreat #4 (DQ)
Panacea
$200 nightly
The price is $220
Oct 15 - Oct 16
Total with taxes and fees
Panacea Cozy Retreat #4 (DQ)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panacea Hotel Reviews

The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida

10/10 Excellent
"Wonderful property! I was looking for a quiet, dog-friendly beach vacation rental and this was the perfect spot! Perfect for long beach walks and our dog had a blast on the beach…true water dog. Owners were very responsive and accommodating. Ate at Angelo’s and 10/10 recommend!The beach was literally in the back yard. It was so easy to just walk out back and go down to the water."
Angela M. 7-night trip
Posted 3 days ago
The Best Beach-Front House “Get-A-Way” in Florida

Find out more about Panacea

Everything you need to know about Panacea vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panacea vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panacea vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panacea vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panacea. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panacea in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $319 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panacea rentals

At Expedia, we put the best Panacea vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panacea rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panacea vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panacea. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panacea?

Yes, there are vacation rentals in Panacea close to Gulf Specimen Public Aquarum, or you can go with a secluded option if you'd like a relaxing place to stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best vacation rentals in Panacea?

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.: Visitors give good reviews to this Panacea vacation home rental, which is located on the beach and has an outdoor pool, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. Some other homes for rent in Panacea include Your Fall Escape: FSU Football & Scalloping and Coastal Getaway on canal-steps to the beach.

How many vacation rentals are there in Panacea?

Choose from 177 Expedia vacation rentals in Panacea for a memorable vacation.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Wilson Beach are other places worth a visit.

What’s a vacation rental in Panacea like?

Vacation rentals are privately owned properties where you can stay for a few weeks or just a few days in Panacea. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.