Title: Visit Santa Clara: 2026 Travel Guide for Santa Clara, Panamá Oeste Province | Expedia.com

[Hotels in Santa Clara](https://expedia.com/Santa-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Vacation Rentals in Santa Clara](https://expedia.com/Santa-Clara-Vacation-Rentals.d553248623287315690.Travel-Guide-VacationRentals)[Flights to Santa Clara](https://expedia.com/Cheap-Flights-To-Santa-Clara.d553248623287315690.Travel-Guide-Flights)[Things to do in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities)[Car Rentals in Santa Clara](https://expedia.com/Car-Rentals-In-Santa-Clara.d553248623287315690.Car-Rental-Guide)[Santa Clara Vacation Packages](https://expedia.com/Santa-Clara.d553248623287315690.Destination-Travel-Guides)

# Santa Clara

## Travel Guide

![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

## Visit Santa Clara

Things to do

- Santa Clara Hotel Deals
- Vacation Rentals in Santa Clara

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

$157 nightly

$172 total

Apr 5 - Apr 6

Total with taxes and fees

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

9/10 Wonderful! (5,153 reviews)

the 15th floor had a little bad scent including my room it was uncomfortable for the first couple hours.

Reviewed on Mar 25, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=3900395&PinnedHotelID=3900395&HadPinnedHotel=true&regionId=553248623287315690)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Sheraton Grand Panama

Via Israel And 77th Street Panama City Panama

$140 nightly

$153 total

Apr 3 - Apr 4

Total with taxes and fees

Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...

8.6/10 Excellent! (1,001 reviews)

Breakfast was great , clean room and staff was nice

Reviewed on Mar 20, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F3%2F2026&endDate=4%2F4%2F2026&selected=1161&PinnedHotelID=1161&HadPinnedHotel=true&regionId=553248623287315690)

![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

$99 nightly

$109 total

Apr 20 - Apr 21

Total with taxes and fees

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

7.8/10 Good! (1,010 reviews)

Nice place for an older hotel. Had fun seeing a pro boxing fight walking distance from Hotel

Reviewed on Mar 24, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F20%2F2026&endDate=4%2F21%2F2026&selected=7164&PinnedHotelID=7164&HadPinnedHotel=true&regionId=553248623287315690)

[See all 1,616 properties in Santa Clara](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F26%2F2026&endDate=3%2F27%2F2026&regionId=553248623287315690)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Arcadia Condo Suites

Calle rio mar Panama City Panamá Province

Stay at this aparthotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Multiplaza Pacific Mall and Avenida Balboa ...

9.4/10 Exceptional! (248 reviews)

The property was amazing but the communication with the host was very bad. None of the communication channels work. Luckily the building’s reception desk compensated and the apartment was very good.

Reviewed on Mar 20, 2026

[](https://expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

![Marriott Executive Apartments Panama City, Finisterre](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/b4d43ebd_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Marriott Executive Apartments Panama City, Finisterre

Calle Colombia Y Ave.,3ra A Sur, Bella V Panama City Panama

Book a stay at this business-friendly aparthotel in Panama City. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our ...

8.8/10 Excellent! (703 reviews)

The accommodations at Marriott Executive Apartments were great. Nice gym that was kept spotless and used daily by guests. The pool was nice, water temperature perfect. Rooms are spacious and have a 2 burner gas cook top for food preparation. Refrigerator, microwave, dishes, utensils, everything you ...

Reviewed on Mar 25, 2026

[](https://expedia.com/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information)

![Casco View Apartments](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Casco View Apartments

C. 16 Oeste Panama City Provincia de Panamá

Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Cinta Costera ...

9/10 Wonderful! (81 reviews)

Quite disappointing. The most obvious reason for the poor review is the immediate area the property is in. I read negative reviews about this but didn’t quite get the full scope of what the neighbouring properties were like until we actually stayed there. When a property is in such a rough area, ...

Reviewed on Mar 24, 2026

[](https://expedia.com/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information)

[See all properties in Santa Clara](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&regionId=553248623287315690&sort=VACATION_RENTAL)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Check Santa Clara hotel availability

[Tonight

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-25&endDate=2026-03-26)[Mar 25 - Mar 26](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-25&endDate=2026-03-26)

[Tomorrow night

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-26&endDate=2026-03-27)[Mar 26 - Mar 27](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=2026-03-26&endDate=2026-03-27)

[This weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)

[Next weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248623287315690&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)

### Popular places to visit

#### Culebra Cut

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area. 

[](https://expedia.com/Culebra-Cut-Santa-Clara.d6078511.Vacation-Attraction)

### Things to do

![Monkey and Sloth Jungle Habitat Panama Tour ](https://mediaim.expedia.com/localexpert/47313144/f3dd1c31-b1f2-41ca-8793-3abcbc166e9d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Monkey and Sloth Jungle Habitat Panama Tour

$36

per adult

**98%** of travellers recommend

[](https://expedia.com/things-to-do/monkey-and-sloth-jungle-habitat-panama-tour.a47313144.activity-details)

![MiraLift](https://mediaim.expedia.com/localexpert/1116180/4f40785f-2369-4d7c-83f7-b0a5cc7ac401.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Transfer to Panama Canal (Miraflores Locks)

$14

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/transfer-to-panama-canal-miraflores-locks.a1116180.activity-details)

![Panamá Canal and Old Town ](https://mediaim.expedia.com/localexpert/46047029/ccc0ec72-b8fd-4f79-8557-c566cdac448f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panamá Canal and Old Town

$80

per adult

[](https://expedia.com/things-to-do/panama-canal-and-old-town.a46047029.activity-details)

![5hour tour of Panama City and Panama Canal - Shared or Private](https://mediaim.expedia.com/localexpert/46748153/8351fdce-6999-4a6c-9037-aa2bc084f123.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### 5hour tour of Panama City and Panama Canal - Shared or Private

$65

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/5hour-tour-of-panama-city-and-panama-canal-shared-or-private.a46748153.activity-details)

![Panama Canal Tour: Miraflores Locks & IMAX Movie - Afternoon](https://mediaim.expedia.com/localexpert/46138380/233a3b35-9fba-421f-b566-37669f374b9d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panama Canal Tour: Miraflores Locks & IMAX Movie - Afternoon

$35

per adult

[](https://expedia.com/things-to-do/panama-canal-tour-miraflores-locks-imax-movie-afternoon.a46138380.activity-details)

![Panama City Tour](https://mediaim.expedia.com/localexpert/1013018/e309936e-dd10-4100-9776-91b585a033e8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panama City Tour (Panama Canal, Old Town And Causeway)

$105

per adult

[](https://expedia.com/things-to-do/panama-city-tour-panama-canal.a1013018.activity-details)

[See all activities in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities)

## Cities near Santa Clara

![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Panama City

![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Colon

![Adobe](https://images.trvl-media.com/place/6025059/97ff43ac-1acd-430b-9f47-7dcfb6cb44b8.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Gamboa

![Adobe](https://images.trvl-media.com/place/553248635921431980/08f3117c-1641-4cbd-a4d6-07c2d5757057.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Ancon

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