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Southeastern Indiana Vacation Rentals

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Our top choices for Southeastern Indiana vacation rentals

House (3 Bedrooms) | Interior
Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!

Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!

3.0 star property
New Albany
10.0 out of 10, Exceptional, (1)
"Amy was wonderful and went above and beyond to make sure we had a great stay. She even left pancakes w/syrup for breakfast and pasta w/sauce in case we didn’t have time to go to the store! It’s the small things that really stick out such as leaving a bowl of snacks, a few beers in the fridge, a bottle of wine, fully stocked medicine cabinet in case you forgot something. She even put food and water out for the dog along with toys and a blanket! We loved being there and it was such a beautiful...
United States
Robin
$345 nightly
The price is $387
Jan 2 - Jan 3, 2026
Total with taxes and fees
Home w/ Fenced Backyard, 6 Mi to Dtwn Louisville!
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
$190 nightly
The price is $213
Dec 14 - Dec 15
Total with taxes and fees
The Reserve on Main
Fridge, microwave, oven, stovetop
Cozy 2-bedroom basement apartment in charming Memphis IN. with WiFi, office area

Cozy 2-bedroom basement apartment in charming Memphis IN. with WiFi, office area

Memphis
10.0 out of 10, Exceptional, (13)
"Property was very clean, smelt great, and spacious. Located in a nice neighborhood. Hosts were extremely accommodating and friendly. Would definitely stay here again if I'm back in the area for an overnight trip. "
United States
Mandy M.
$140 nightly
The price is $158
Dec 10 - Dec 11
Total with taxes and fees
Cozy 2-bedroom basement apartment in charming Memphis IN. with WiFi, office area
Property grounds
Cozy Country Cabin quiet country retreat

Cozy Country Cabin quiet country retreat

Orleans
10.0 out of 10, Exceptional, (188)
"We really enjoyed our stay. The cabin is very nice and so is the pond."
United States
Scott H.
$173 nightly
The price is $191
Dec 10 - Dec 11
Total with taxes and fees
Cozy Country Cabin quiet country retreat
Interior
Charming 1-bedroom carriage house in delightful Charlestown with WiFi, AC

Charming 1-bedroom carriage house in delightful Charlestown with WiFi, AC

Charlestown
10.0 out of 10, Exceptional, (12)
"The property was clean and quiet. Great location in a nice residential neighborhood. Very close to Charlestown State Park where we did some hiking."
United States
Chris S.
$130 nightly
The price is $147
Dec 10 - Dec 11
Total with taxes and fees
Charming 1-bedroom carriage house in delightful Charlestown with WiFi, AC
Exterior
Cozy Tiny House in Scottsburg

Cozy Tiny House in Scottsburg

Scottsburg
9.6 out of 10, Exceptional, (4)
"Cute, clean, and comfortable stay! Great communication with host! "
United States
Teresa B.
$154 nightly
The price is $172
Dec 29 - Dec 30
Total with taxes and fees
Cozy Tiny House in Scottsburg
Full-size fridge, microwave, oven, stovetop
The Duke Hotel

The Duke Hotel

2.0 star property
Downtown Louisville
$142 nightly
The price is $164
Dec 10 - Dec 11
Total with taxes and fees
The Duke Hotel
Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down comforters, memory foam beds
Stellar Suites

Stellar Suites

4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
$152 nightly
The price is $177
Dec 25 - Dec 26
Total with taxes and fees
Stellar Suites
Fridge, microwave, oven, stovetop
Secretariat Twin Spires Suite!

Secretariat Twin Spires Suite!

Jeffersonville
10.0 out of 10, Exceptional, (2)
"A wonderful place in a wonderful location. Walking distance to almost everything. Host was extremely helpful and made our stay unforgettable. The unit itself is very nice with easy access in and out. Lots of parking in the back. I would definitely recommend. "
United States
Drew J.
$120 nightly
The price is $123
Dec 11 - Dec 12
Total with taxes and fees
Secretariat Twin Spires Suite!
Fridge, microwave, oven, stovetop
The Blue Door Place

The Blue Door Place

Florence
9.6 out of 10, Exceptional, (18)
"Perfect spot "
United States
Damon G.
$120 nightly
The price is $134
Dec 10 - Dec 11
Total with taxes and fees
The Blue Door Place
Fridge, microwave, oven, stovetop
Relax, min from Louisville, Pet friendly, Entire house- fenced in backyard.

Relax, min from Louisville, Pet friendly, Entire house- fenced in backyard.

New Albany
10.0 out of 10, Exceptional, (34)
"Property is great for those traveling with pets. Yard big enough to play. New Albany great location with restaurants close by. Really nice greenway along the river as well. All in all I would highly recommend this property. "
United States
Robin S.
$173 nightly
The price is $195
Dec 14 - Dec 15
Total with taxes and fees
Relax, min from Louisville, Pet friendly, Entire house- fenced in backyard.
Exterior
Cozy 2-bedroom country side cabin. Minutes from Patoka Lake. Pet friendly.

Cozy 2-bedroom country side cabin. Minutes from Patoka Lake. Pet friendly.

Paoli
9.8 out of 10, Exceptional, (27)
"Perfect spot for off grid getaway. Very nice cabin and location. "
United States
Peter W.
$205 nightly
The price is $228
Dec 11 - Dec 12
Total with taxes and fees
Cozy 2-bedroom country side cabin. Minutes from Patoka Lake. Pet friendly.
Private kitchen
Putt Putt House by Louisville Walking Bridge

Putt Putt House by Louisville Walking Bridge

2.0 star property
Jeffersonville
10.0 out of 10, Exceptional, (9)
"Beautiful property in lovely area "
United States
A. Dawn
$260 nightly
The price is $294
Dec 21 - Dec 22
Total with taxes and fees
Putt Putt House by Louisville Walking Bridge
Terrace/patio
Dream Getaway Cottage w/ Endless Hilltop Views - Seasonal Pool/Hot Tub

Dream Getaway Cottage w/ Endless Hilltop Views - Seasonal Pool/Hot Tub

Paoli
9.2 out of 10, Wonderful, (27)
"Beautiful view and great accommodations"
United States
Janice H.
$251 nightly
The price is $279
Dec 10 - Dec 11
Total with taxes and fees
Dream Getaway Cottage w/ Endless Hilltop Views - Seasonal Pool/Hot Tub
2 bedrooms, desk, iron/ironing board, WiFi
Charming Churchill Downs Cottage

Charming Churchill Downs Cottage

Old Louisville
9.2 out of 10, Wonderful, (26)
"Nice quite location i thought "
United States
josh b.
$199 nightly
The price is $233
Dec 10 - Dec 11
Total with taxes and fees
Charming Churchill Downs Cottage
Exterior detail
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
$334 nightly
The price is $352
Dec 31 - Jan 1, 2026
Total with taxes and fees
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Interior
Cozy Riverside Apt. Min to Downtown Louisville. King Bed, Coffee Bar!

Cozy Riverside Apt. Min to Downtown Louisville. King Bed, Coffee Bar!

Jeffersonville
9.8 out of 10, Exceptional, (28)
"The apartment is very cute. the location was great. I was within walking distance of many cool spots and only steps from the river. The host is very polite and friendly. I would recommend this to anyone looking to stay near Louisville."
United States
Holly W.
$120 nightly
The price is $136
Dec 22 - Dec 23
Total with taxes and fees
Cozy Riverside Apt. Min to Downtown Louisville. King Bed, Coffee Bar!
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

4.0 star property
Downtown Louisville
8.2 out of 10, Very Good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
$173 nightly
The price is $201
Dec 10 - Dec 11
Total with taxes and fees
CozySuites at Nulu
Property grounds
Hometown on Main Street, Suite 102, Charlottes corner overlook, Suite 102

Hometown on Main Street, Suite 102, Charlottes corner overlook, Suite 102

Madison
9.8 out of 10, Exceptional, (10)
"Super comfortable, clean little apartment in a quiet area off the main strip. We loved out stay!"
United States
Courtney G.
$127 nightly
The price is $130
Dec 22 - Dec 23
Total with taxes and fees
Hometown on Main Street, Suite 102, Charlottes corner overlook, Suite 102
Exterior detail
Contemporary Studio in NuLu Arts District

Contemporary Studio in NuLu Arts District

Downtown Louisville
10.0 out of 10, Exceptional, (11)
"Clean and comfortable, great location."
United States
Robyn K.
$140 nightly
The price is $162
Dec 10 - Dec 11
Total with taxes and fees
Contemporary Studio in NuLu Arts District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeastern Indiana Hotel Reviews

Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

10/10 Excellent
"Room clean and staff friendly"
manuel 4-night trip
Posted 1 day ago
Sheraton Louisville Riverside by Marriott

Find out more about Southeastern Indiana

Everything you need to know about Southeastern Indiana vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southeastern Indiana vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

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Southeastern Indiana vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Southeastern Indiana. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southeastern Indiana in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $177 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

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