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Find All Southern Illinois Hotels
We have found 1095 Southern Illinois Hotels
- Super 8 by Wyndham O'Fallon
- Drury Plaza Hotel Mt. Vernon
- Drury Inn & Suites Marion
- Comfort Suites Mount Vernon
- Drury Inn & Suites St. Louis Fairview Heights
- Quality Inn & Suites near St. Louis and I-255
- Baymont by Wyndham Effingham
- Best Western Plus Pontoon Beach
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Super 8 by Wyndham Troy IL/St. Louis Area
- Red Lion Inn & Suites Pontoon Beach
- Drury Inn & Suites St. Louis O'Fallon, IL
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Quality Inn O'Fallon IL - St. Louis
- Comfort Inn Collinsville near St. Louis
- Best Western Delta Inn
- Baymont by Wyndham Marion
- Motel 6 Caseyville, IL - Caseyville Il
- Super 8 by Wyndham Fairview Heights-St. Louis
- Super 8 by Wyndham Marion
- Holiday Inn Express Metropolis by IHG
- The Principal Hotel
- Comfort Suites Mattoon East
- Sleep Inn O'Fallon near I-64
- Radisson Hotel Fairview Heights - St. Louis
- Holiday Inn Express & Suites Edwardsville by IHG
- Best Western Plus MidAmerica Hotel
- Holiday Inn Express Troy by IHG
- Drury Inn & Suites St. Louis Collinsville
- Holiday Inn Express & Suites Mount Vernon by IHG
- Baymont by Wyndham O'Fallon St. Louis Area
- Best Western Marion Hotel
- DoubleTree by Hilton Collinsville - St. Louis
- Days Inn by Wyndham Collinsville/St. Louis
- Comfort Inn Edwardsville - St. Louis
- Holiday Inn Carbondale-Conference Center by IHG
- Super 8 by Wyndham Carbondale
- University Inn of Carbondale
- Best Western Troy Hotel
- Quality Inn And Suites
- La Quinta Inn & Suites by Wyndham Effingham
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Days Inn by Wyndham Pontoon Beach
- Holiday Inn Express & Suites Effingham by IHG
- DoubleTree by Hilton Mt. Vernon
- Comfort Inn & Suites Marion I-57
- Country Inn & Suites by Radisson, Effingham, IL
- Best Western U. S. Inn
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Americas Best Value Inn Collinsville St. Louis
- Super 8 by Wyndham Mt. Vernon IL
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Red Roof Inn St Louis - Troy, IL
- Candlewood Suites O Fallon by IHG
- Super 8 by Wyndham Grayville
- Country Hearth Inn & Suites Edwardsville St. Louis
- Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
- Country View Inn & Suites
- Days Inn & Suites by Wyndham Casey
- Royal Relax Inn
- Hampton Inn Carbondale
- SureStay Hotel by Best Western Whittington Rend Lake
- Quality Inn & Suites Metropolis I-24
- Quality Inn & Suites Caseyville - St. Louis
- Baymont by Wyndham Chester IL
- Days Inn by Wyndham Mount Vernon
- Economy Inn & Suites
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Country Inn & Suites by Radisson, Marion, IL
- Hampton Inn & Suites Effingham
- Best Western Saluki Inn
- Hampton Inn & Suites St. Louis-Edwardsville
- Unique Suites Hotel
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- Motel 6 Marion, IL
- Bel Air Motel
- Days Inn & Suites by Wyndham Caseyville
- Super 8 by Wyndham Collinsville St. Louis
- Comfort Inn & Suites Carbondale University Area
- Seasons Inn & Suites Highland
- Cobblestone Inn & Suites - Altamont
- Quality Inn Mount Vernon, IL
- Americas Best Value Inn Marion, IL
- Super 8 by Wyndham Belleville St. Louis Area
- Days Inn by Wyndham Troy IL
- Hampton Inn St. Louis - Columbia
- Quality Inn Effingham North
- Econo Lodge Inn & Suites Fairview Heights - St. Louis
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Hampton Inn O'Fallon
- First Western Inn
- Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
- Holiday Inn Express & Suites Mattoon by IHG
- Best Western Flora Inn
- Holiday Inn St. Louis Fairview Heights by IHG
- Motel 6 Troy, IL
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.