$145 Cheap Flights from Hyannis (HYA) to San Francisco (SFO)

View $145 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from Hyannis, MA (HYA-Barnstable Municipal) to San Francisco Intl. Airport (SFO)

Cheap Flights from Hyannis to San Francisco (HYA-SFO)

Prices were available within the past 7 days and start at $145 for one-way flights and $291 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Sat, Sep 6 - Mon, Sep 8
HYA
Hyannis
SFO
San Francisco
$291 Roundtrip, found 5 days ago
$291
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Sat, Sep 6 from Hyannis to San Francisco, returning Mon, Sep 8, priced at $291 found 5 days ago
JetBlue Airways
Sat, Sep 6 - Sun, Sep 7
HYA
Hyannis
SFO
San Francisco
$328 Roundtrip, found 5 days ago
$328
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Sat, Sep 6 from Hyannis to San Francisco, returning Sun, Sep 7, priced at $328 found 5 days ago
JetBlue Airways
Fri, Aug 29 - Sat, Sep 6
HYA
Hyannis
SFO
San Francisco
$351 Roundtrip, found 4 days ago
$351
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Fri, Aug 29 from Hyannis to San Francisco, returning Sat, Sep 6, priced at $351 found 4 days ago
JetBlue Airways
Fri, Aug 29 - Sun, Sep 7
HYA
Hyannis
SFO
San Francisco
$398 Roundtrip, found 4 days ago
$398
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Fri, Aug 29 from Hyannis to San Francisco, returning Sun, Sep 7, priced at $398 found 4 days ago
JetBlue Airways
Wed, Sep 3 - Sat, Sep 6
HYA
Hyannis
SFO
San Francisco
$405 Roundtrip, found 5 days ago
$405
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Wed, Sep 3 from Hyannis to San Francisco, returning Sat, Sep 6, priced at $405 found 5 days ago
JetBlue Airways
Sat, Aug 30 - Wed, Sep 3
HYA
Hyannis
SFO
San Francisco
$428 Roundtrip, found 3 days ago
$428
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sat, Aug 30 from Hyannis to San Francisco, returning Wed, Sep 3, priced at $428 found 3 days ago
JetBlue Airways
Wed, Sep 3 - Sun, Sep 7
HYA
Hyannis
SFO
San Francisco
$445 Roundtrip, found 8 hours ago
$445
Roundtrip
found 8 hours ago
Select JetBlue Airways flight, departing Wed, Sep 3 from Hyannis to San Francisco, returning Sun, Sep 7, priced at $445 found 8 hours ago
JetBlue Airways
Tue, Aug 26 - Sat, Sep 6
HYA
Hyannis
SFO
San Francisco
$466 Roundtrip, found 4 days ago
$466
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Tue, Aug 26 from Hyannis to San Francisco, returning Sat, Sep 6, priced at $466 found 4 days ago
American Airlines
Sat, Aug 23 - Mon, Sep 1
HYA
Hyannis
SFO
San Francisco
$483 Roundtrip, found 6 days ago
$483
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Aug 23 from Hyannis to San Francisco, returning Mon, Sep 1, priced at $483 found 6 days ago
Cape Air
Mon, Sep 22 - Wed, Oct 1
HYA
Hyannis
SFO
San Francisco
$571 Roundtrip, found 5 days ago
$571
Roundtrip
found 5 days ago
Select Cape Air flight, departing Mon, Sep 22 from Hyannis to San Francisco, returning Wed, Oct 1, priced at $571 found 5 days ago
Flights from Hyannis (HYA) to San Francisco (SFO)
Origin airport
Barnstable Municipal
Destination airport
San Francisco Intl.
Roundtrip price
$291
Distance
2743 mi

Hyannis to San Francisco Flights

The cheapest times to fly from Hyannis to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Hyannis to San Francisco are during the month of September. You can find some of the cheapest flights from Hyannis to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Hyannis to San Francisco

Sunday is one of the best days to book for cheap flights from Hyannis to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Hyannis to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Hyannis to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $145 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Hyannis to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Hyannis to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO) cost?
Get a cheap one-way flight from $145 or cheap return flight from $291 from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO)?
The cheapest month to fly from HYA to SFO is September, when there's less demand. Off-peak months are generally when better flight deals are available between these airports.
Which airlines fly direct from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO)?
You can't fly nonstop from Hyannis, MA (HYA-Barnstable Municipal) to San Francisco Intl. Airport (SFO). However, you can seamlessly travel to San Francisco without any layovers by taking off from Logan Intl. Airport (BOS).
What is the cheapest airline that flies from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline flying from HYA to SFO, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO)?
There are no daily nonstop flights from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from HYA to SFO?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO)?
Choose a flight from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO) last-minute?
Booking your plane ticket from HYA to SFO just before your journey is usually more expensive. However, if you're flexible with your departure times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a HYA to SFO flight and hotel package?
Compared with arranging hotels and flights separately, booking a HYA to SFO flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place will take the stress out of travel planning. Simply pick your flights and select from our extensive range of stays, then tailor your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Barnstable Municipal Airport (HYA) to San Francisco Intl. Airport (SFO)?
In most instances, you can modify or cancel your HYA to SFO flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you'd like more details, go to our Customer Service portal.

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*Available to One Key members.