$333 Cheap Flights from Panama City (PTY) to Lexington (LEX)

View $333 flight on Thu, Oct 9, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX)

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Cheap Flights from Panama City to Lexington (PTY-LEX)

Prices were available within the past 7 days and start at $333 for one-way flights and $552 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jan 13 - Tue, Jan 27
PTY
Panama City
LEX
Lexington
$552 Roundtrip, found 5 days ago
$552
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 13 from Panama City to Lexington, returning Tue, Jan 27, priced at $552 found 5 days ago
United
Tue, Oct 28 - Mon, Nov 17
PTY
Panama City
LEX
Lexington
$552 Roundtrip, found 2 days ago
$552
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 28 from Panama City to Lexington, returning Mon, Nov 17, priced at $552 found 2 days ago
United
Mon, Oct 20 - Wed, Nov 5
PTY
Panama City
LEX
Lexington
$574 Roundtrip, found 2 days ago
$574
Roundtrip
found 2 days ago
Select United flight, departing Mon, Oct 20 from Panama City to Lexington, returning Wed, Nov 5, priced at $574 found 2 days ago
United
Tue, Oct 28 - Thu, Nov 13
PTY
Panama City
LEX
Lexington
$581 Roundtrip, found 2 days ago
$581
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 28 from Panama City to Lexington, returning Thu, Nov 13, priced at $581 found 2 days ago
United
Sun, Oct 26 - Wed, Nov 5
PTY
Panama City
LEX
Lexington
$595 Roundtrip, found 2 days ago
$595
Roundtrip
found 2 days ago
Select United flight, departing Sun, Oct 26 from Panama City to Lexington, returning Wed, Nov 5, priced at $595 found 2 days ago
United
Mon, Oct 6 - Tue, Oct 21
PTY
Panama City
LEX
Lexington
$601 Roundtrip, found 2 days ago
$601
Roundtrip
found 2 days ago
Select United flight, departing Mon, Oct 6 from Panama City to Lexington, returning Tue, Oct 21, priced at $601 found 2 days ago
United
Mon, Oct 27 - Thu, Nov 13
PTY
Panama City
LEX
Lexington
$602 Roundtrip, found 2 days ago
$602
Roundtrip
found 2 days ago
Select United flight, departing Mon, Oct 27 from Panama City to Lexington, returning Thu, Nov 13, priced at $602 found 2 days ago
American Airlines
Tue, Jan 13 - Tue, Jan 27
PTY
Panama City
LEX
Lexington
$605 Roundtrip, found 5 days ago
$605
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 13 from Panama City to Lexington, returning Tue, Jan 27, priced at $605 found 5 days ago
American Airlines
Tue, Jan 13 - Tue, Jan 27
PTY
Panama City
LEX
Lexington
$610 Roundtrip, found 5 days ago
$610
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 13 from Panama City to Lexington, returning Tue, Jan 27, priced at $610 found 5 days ago
Delta
Tue, Oct 21 - Tue, Nov 4
PTY
Panama City
LEX
Lexington
$612 Roundtrip, found 2 days ago
$612
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Oct 21 from Panama City to Lexington, returning Tue, Nov 4, priced at $612 found 2 days ago

Alternative airports near Lexington

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Blue Grass LEX. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $692
LEX
Blue Grass
CheapestClosest
Average driving time to city center9 min
Flights from $692
Flights from Panama City (PTY) to Lexington (LEX)
Origin airport
Tocumen Intl.
Destination airport
Blue Grass
Airlines serving
American Airlines, Delta, United
Roundtrip price
$552
Distance
2027 mi

Panama City to Lexington Flights

The cheapest times to fly from Panama City to Lexington

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Lexington are during the month of January. You can find some of the cheapest flights from Panama City to Lexington with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Lexington

Sunday is one of the best days to book for cheap flights from Panama City to Lexington: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Lexington

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Lexington in 2025. You can also book with separate airlines for your outbound and return journeys, from $333 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Lexington flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Lexington airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX) cost?
Grab a cheap one-way flight from $333 or cheap return flight from $552 from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX)?
Planning your getaway for January is a great way to save, as it's the cheapest month for flights between PTY and LEX. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from PTY to LEX. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX)?
Nonstop flights from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PTY to LEX?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX)?
Choose a flight from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX) last-minute?
Booking your ticket from PTY to LEX shortly before your getaway is usually more expensive. However, if you're flexible with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book a PTY to LEX flight and hotel package?
Opting for a PTY to LEX flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our extensive range of hotels and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Blue Grass Airport (LEX)?
In most cases, you're able to cancel or reschedule your PTY to LEX flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you need more information, go to our Customer Service portal.

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*Available to One Key members.