$292 Cheap Flights from Panama City (PTY) to Quito (UIO)

View $292 flight on Sun, Aug 10, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)

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Cheap Flights from Panama City to Quito (PTY-UIO)

Prices were available within the past 7 days and start at $292 for one-way flights and $448 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, Oct 16 - Wed, Oct 22
PTY
Panama City
UIO
Quito
$448 Roundtrip, found 8 hours ago
$448
Roundtrip
found 8 hours ago
Select Copa flight, departing Thu, Oct 16 from Panama City to Quito, returning Wed, Oct 22, priced at $448 found 8 hours ago
Copa
Fri, Aug 22 - Mon, Aug 25
PTY
Panama City
UIO
Quito
$451 Roundtrip, found 1 day ago
$451
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Aug 22 from Panama City to Quito, returning Mon, Aug 25, priced at $451 found 1 day ago
Copa
Thu, Jan 15 - Tue, Jan 20
PTY
Panama City
UIO
Quito
$453 Roundtrip, found 3 hours ago
$453
Roundtrip
found 3 hours ago
Select Copa flight, departing Thu, Jan 15 from Panama City to Quito, returning Tue, Jan 20, priced at $453 found 3 hours ago
Copa
Thu, Oct 16 - Wed, Oct 22
PTY
Panama City
UIO
Quito
$459 Roundtrip, found 8 hours ago
$459
Roundtrip
found 8 hours ago
Select Copa flight, departing Thu, Oct 16 from Panama City to Quito, returning Wed, Oct 22, priced at $459 found 8 hours ago
Copa
Thu, Oct 16 - Wed, Oct 22
PTY
Panama City
UIO
Quito
$459 Roundtrip, found 8 hours ago
$459
Roundtrip
found 8 hours ago
Select Copa flight, departing Thu, Oct 16 from Panama City to Quito, returning Wed, Oct 22, priced at $459 found 8 hours ago
Copa
Fri, Aug 22 - Mon, Aug 25
PTY
Panama City
UIO
Quito
$462 Roundtrip, found 1 day ago
$462
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Aug 22 from Panama City to Quito, returning Mon, Aug 25, priced at $462 found 1 day ago
Copa
Fri, Aug 22 - Mon, Aug 25
PTY
Panama City
UIO
Quito
$462 Roundtrip, found 1 day ago
$462
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Aug 22 from Panama City to Quito, returning Mon, Aug 25, priced at $462 found 1 day ago
Copa
Thu, Jan 15 - Tue, Jan 20
PTY
Panama City
UIO
Quito
$464 Roundtrip, found 3 hours ago
$464
Roundtrip
found 3 hours ago
Select Copa flight, departing Thu, Jan 15 from Panama City to Quito, returning Tue, Jan 20, priced at $464 found 3 hours ago
Copa
Tue, Aug 12 - Tue, Aug 19
PTY
Panama City
UIO
Quito
$470 Roundtrip, found 1 day ago
$470
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Aug 12 from Panama City to Quito, returning Tue, Aug 19, priced at $470 found 1 day ago
avianca
Mon, Aug 11 - Sat, Aug 16
PTY
Panama City
UIO
Quito
$580 Roundtrip, found 1 day ago
$580
Roundtrip
found 1 day ago
Select avianca flight, departing Mon, Aug 11 from Panama City to Quito, returning Sat, Aug 16, priced at $580 found 1 day ago

Find the cheapest month to fly from Panama City (PTY) to Quito (UIO)

June is typically the cheapest month to fly

From $264 - $574 per traveler.

Graph displaying average flight prices per month

Alternative airports near Quito

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Mariscal Sucre Intl. UIO. Cheapest and Closest option available. Average driving time to city center is 33 minutes. Flights from $499
UIO
Mariscal Sucre Intl.
CheapestClosest
Average driving time to city center33 min
Flights from $499
0
Flights from Panama City (PTY) to Quito (UIO)
Origin airport
Tocumen Intl.
Destination airport
Mariscal Sucre Intl.
Airlines serving
Copa, avianca
Roundtrip price
$448
Distance
638 mi

Panama City to Quito Flights

The cheapest times to fly from Panama City to Quito

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Quito are during the month of October. You can find some of the cheapest flights from Panama City to Quito with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Quito

Sunday is one of the best days to book for cheap flights from Panama City to Quito: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Quito

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Quito in 2025. You can also book with separate airlines for your outbound and return journeys, from $292 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Quito flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Quito airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) cost?
Cheap return flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) start at $453. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving PTY on August 19 2025 and touching down at UIO. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from PTY to UIO?
The cheapest flights from PTY to UIO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
When jetting out of Tocumen Intl. Airport (PTY), you can jump on a nonstop flight to Mariscal Sucre Intl. Airport (UIO) with Copa Airlines.
What is the cheapest airline that flies from PTY to UIO?
With prices as low as $545 for a one-way journey from PTY to UIO, Copa is currently the cheapest carrier for this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PTY on July 31 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
With, on average, 4 nonstop flights that operate from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) each day, you'll be on your way in no time.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
More travelers fly between PTY and UIO at 6 PM than at any other time of day. Rather skip the crowds? Travel outside of rush hours and you could save on your fare as well.
What day of the week has the most flights from PTY to UIO?
Friday has the most flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO). Consider leaving on this day and you'll have a greater chance of finding a schedule that works for you.
What is the earliest flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
Catch the earliest flight at around 9:47AM UTC-5, heading out of Tocumen Intl. Airport (PTY). You'll be traveling for approximately 2h 4m, arriving at Mariscal Sucre Intl. Airport (UIO) at approximately 11:51AM UTC-5.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
The average flight time from PTY to UIO is 2 hours and 4 minutes, covering a distance of 640 mi.
What airline has the least delays from PTY to UIO?
With 92% of journeys generally arriving on schedule, Copa Airlines has the best on-time performance for direct flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO). To keep track of your flight status and receive notifications if anything changes, simply head to the Expedia App.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
Opt for a flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) that takes off before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Quito from Tocumen Intl. Airport (PTY)?
Compare your flight options from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO). This is the only airport in Quito you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) last-minute?
Last-minute bookings from PTY to UIO are typically more expensive. To lock in the best prices, start searching for flights ahead of time. That said, if you're flexible with your travel dates, it's possible to find a cheap ticket right before your trip.
Is it cheaper to book a PTY to UIO flight and hotel package?
You'll typically save money by booking a PTY to UIO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After choosing your ideal flights and accommodations, consider adding extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
Typically, it's possible to cancel or reschedule your PTY to UIO flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.