$455 Cheap Flights from Santa Cruz (VVI) to San Francisco (SFO)

View $455 flight on Thu, Nov 27, 2025Opens in a new window

Popular airlines from Santa Cruz (VVI-Viru Viru Intl.) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Santa Cruz to San Francisco (VVI-SFO)

Prices were available within the past 7 days and start at $455 for one-way flights and $784 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Oct 3 - Mon, Oct 6
VVI
Santa Cruz
SFO
San Francisco
$784 Roundtrip, found 6 days ago
$784
Roundtrip
found 6 days ago
Select Copa flight, departing Fri, Oct 3 from Santa Cruz to San Francisco, returning Mon, Oct 6, priced at $784 found 6 days ago
avianca
Fri, Jan 30 - Mon, Feb 2
VVI
Santa Cruz
SFO
San Francisco
$788 Roundtrip, found 6 days ago
$788
Roundtrip
found 6 days ago
Select avianca flight, departing Fri, Jan 30 from Santa Cruz to San Francisco, returning Mon, Feb 2, priced at $788 found 6 days ago
United
Mon, Sep 29 - Thu, Oct 16
VVI
Santa Cruz
SFO
San Francisco
$806 Roundtrip, found 2 days ago
$806
Roundtrip
found 2 days ago
Select United flight, departing Mon, Sep 29 from Santa Cruz to San Francisco, returning Thu, Oct 16, priced at $806 found 2 days ago
United
Fri, Jan 30 - Mon, Feb 2
VVI
Santa Cruz
SFO
San Francisco
$807 Roundtrip, found 6 days ago
$807
Roundtrip
found 6 days ago
Select United flight, departing Fri, Jan 30 from Santa Cruz to San Francisco, returning Mon, Feb 2, priced at $807 found 6 days ago
Copa
Tue, Sep 9 - Mon, Nov 3
VVI
Santa Cruz
SFO
San Francisco
$811 Roundtrip, found 1 hour ago
$811
Roundtrip
found 1 hour ago
Select Copa flight, departing Tue, Sep 9 from Santa Cruz to San Francisco, returning Mon, Nov 3, priced at $811 found 1 hour ago
avianca
Thu, Oct 2 - Thu, Oct 16
VVI
Santa Cruz
SFO
San Francisco
$814 Roundtrip, found 2 days ago
$814
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Oct 2 from Santa Cruz to San Francisco, returning Thu, Oct 16, priced at $814 found 2 days ago
United
Fri, Oct 3 - Mon, Oct 6
VVI
Santa Cruz
SFO
San Francisco
$816 Roundtrip, found 6 days ago
$816
Roundtrip
found 6 days ago
Select United flight, departing Fri, Oct 3 from Santa Cruz to San Francisco, returning Mon, Oct 6, priced at $816 found 6 days ago
avianca
Wed, Sep 10 - Thu, Oct 30
VVI
Santa Cruz
SFO
San Francisco
$818 Roundtrip, found 1 hour ago
$818
Roundtrip
found 1 hour ago
Select avianca flight, departing Wed, Sep 10 from Santa Cruz to San Francisco, returning Thu, Oct 30, priced at $818 found 1 hour ago
United
Wed, Sep 10 - Thu, Oct 30
VVI
Santa Cruz
SFO
San Francisco
$819 Roundtrip, found 1 hour ago
$819
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Sep 10 from Santa Cruz to San Francisco, returning Thu, Oct 30, priced at $819 found 1 hour ago
GOL Linhas Aereas S.A.
Sat, Oct 4 - Thu, Oct 16
VVI
Santa Cruz
SFO
San Francisco
$832 Roundtrip, found 2 days ago
$832
Roundtrip
found 2 days ago
Select GOL Linhas Aereas S.A. flight, departing Sat, Oct 4 from Santa Cruz to San Francisco, returning Thu, Oct 16, priced at $832 found 2 days ago
Flights from Santa Cruz (VVI) to San Francisco (SFO)
Origin airport
Viru Viru Intl.
Destination airport
San Francisco Intl.
Airlines serving
Copa, GOL Linhas Aereas S.A., United, avianca
Roundtrip price
$783
Distance
5417 mi

Santa Cruz to San Francisco Flights

The cheapest times to fly from Santa Cruz to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santa Cruz to San Francisco are during the month of October. You can find some of the cheapest flights from Santa Cruz to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santa Cruz to San Francisco

Sunday is one of the best days to book for cheap flights from Santa Cruz to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santa Cruz to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santa Cruz to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $455 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santa Cruz to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santa Cruz to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO) cost?
Snag a cheap one-way flight from $455 or cheap return flight from $784 from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO)?
October is the least expensive month to fly from VVI to SFO. Timing your trip outside of the busy season is often the key to better flight prices.
What is the cheapest airline that flies from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline that'll fly you from VVI to SFO, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO)?
You'll have to book a flight with a layover when traveling from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from VVI to SFO?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change depending on a number of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO)?
To avoid potential delays on the Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO) last-minute?
Last-minute bookings from VVI to SFO are typically more expensive. To lock in the best prices, start looking for flights early. That being said, if you're flexible with your travel plans, you may find a cheap ticket right before your journey.
Is it cheaper to book a VVI to SFO flight and hotel package?
Securing a VVI to SFO flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Select from our wide range of hotels and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Viru Viru Intl. Airport (VVI) to San Francisco Intl. Airport (SFO)?
Typically, you can modify or cancel your VVI to SFO flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you need further details, head to our Customer Service portal.

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*Available to One Key members.