$130 Cheap American Airlines flights Lexington (LEX) to Myrtle Beach (MYR)

Scoring cheap one-way American Airlines flights from LEX to MYR from $130 on Expedia couldn’t be simpler — just filter by “Price (lowest to highest).” Or check out our budget-friendly round-trip fares from $229 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to jet off to Myrtle Beach with American Airlines. You could also find great prices on one-way and return tickets in November.

Look for affordable American Airlines flights from Blue Grass Airport (LEX) to Myrtle Beach Intl. Airport (MYR) one to three months ahead of your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and journey, the best day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Simply enter your dates, press search and select “Nonstop” on Expedia to browse any direct flights from LEX to MYR with American Airlines or other airlines.

Browse American Airlines’s earliest flights from LEX to MYR by checking our “Morning” and “Early Morning” filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Jump on an American Airlines flight from Blue Grass Airport (LEX) to Myrtle Beach, and you’ll likely come in to Myrtle Beach Intl. Airport (MYR). This is the airline’s primary hub here.

Typically, you can cancel or change your flight, although there may be additional fees if your booking was made more than 24 hours ago. Need flexible options? Make use of Expedia’s “No cancel fee” or “Changes included” filter to find flights that won’t charge extra if you have to revise your plans. To make modifications, visit “Trips,” select your flight and click on “Manage Booking” for more details.