$317 Cheap American Airlines flights Columbia (COU) to San Diego (SAN)

You'll discover cheap return American Airlines flights from $370 from COU to SAN by organizing your results from "Price (lowest to highest)" on Expedia. Or look for options from $317 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your travel date to get cheaper fares on American Airlines flights from Columbia Regional Airport (COU) to San Diego Intl. Airport (SAN). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to browse the earliest flights from COU to SAN. Jetting off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.