$607 Cheap American Airlines flights Rome (FCO) to San Diego (SAN)

You can find affordable return American Airlines flights from $901 from FCO to SAN by filtering your results from "Price (lowest to highest)" on Expedia. Or look for deals from $607 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for American Airlines flights from FCO to SAN about one month before you want to leave. The cheapest time to book an international flight is generally 18 to 29 days ahead of your departure date when you can save 17% versus booking four to five months in advance. No matter your fare class or itinerary, the best day to book international airfare is usually Sunday. Friday can be the most expensive. Travelers booking on a Sunday can save an average of 17% compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse American Airlines's earliest flights from FCO to SAN by selecting the "Early Morning" and "Morning" filters. Not only will you get to where you're going sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.