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$115 Cheap Flights from Columbus (CMH) to St. Louis (STL)

View $115 flight on Wed, Oct 7, 2026Opens in a new window

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Columbus to St. Louis (CMH-STL)

Prices were available within the past 7 days and start at $115 for one-way flights and $133 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Tue, Oct 6 - Mon, Oct 12
CMH
Columbus
STL
St. Louis
$133 Roundtrip, found 6 days ago
$133
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Tue, Oct 6 from Columbus to St. Louis, returning Mon, Oct 12, priced at $133 found 6 days ago
Frontier Airlines
Thu, Oct 1 - Mon, Oct 12
CMH
Columbus
STL
St. Louis
$138 Roundtrip, found 6 days ago
$138
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Oct 1 from Columbus to St. Louis, returning Mon, Oct 12, priced at $138 found 6 days ago
Frontier Airlines
Wed, Oct 7 - Sat, Oct 24
CMH
Columbus
STL
St. Louis
$238 Roundtrip, found 3 days ago
$238
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Oct 7 from Columbus to St. Louis, returning Sat, Oct 24, priced at $238 found 3 days ago
Southwest Airlines
Mon, Nov 9 - Tue, Nov 10
CMH
Columbus
STL
St. Louis
$240 Roundtrip, found 21 hours ago
$240
Roundtrip
found 21 hours ago
Select Southwest Airlines flight, departing Mon, Nov 9 from Columbus to St. Louis, returning Tue, Nov 10, priced at $240 found 21 hours ago
Frontier Airlines
Wed, Dec 2 - Thu, Jan 7
CMH
Columbus
STL
St. Louis
$243 Roundtrip, found 8 hours ago
$243
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Wed, Dec 2 from Columbus to St. Louis, returning Thu, Jan 7, priced at $243 found 8 hours ago
Frontier Airlines
Fri, Oct 30 - Mon, Nov 2
CMH
Columbus
STL
St. Louis
$245 Roundtrip, found 2 days ago
$245
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Oct 30 from Columbus to St. Louis, returning Mon, Nov 2, priced at $245 found 2 days ago
Southwest Airlines
Thu, Oct 29 - Tue, Nov 3
CMH
Columbus
STL
St. Louis
$245 Roundtrip, found 1 day ago
$245
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Oct 29 from Columbus to St. Louis, returning Tue, Nov 3, priced at $245 found 1 day ago
American Airlines
Thu, Oct 29 - Mon, Nov 2
CMH
Columbus
STL
St. Louis
$255 Roundtrip, found 4 hours ago
$255
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Oct 29 from Columbus to St. Louis, returning Mon, Nov 2, priced at $255 found 4 hours ago
Delta
Thu, Oct 29 - Mon, Nov 2
CMH
Columbus
STL
St. Louis
$255 Roundtrip, found 4 hours ago
$255
Roundtrip
found 4 hours ago
Select Delta flight, departing Thu, Oct 29 from Columbus to St. Louis, returning Mon, Nov 2, priced at $255 found 4 hours ago
United
Thu, Oct 29 - Mon, Nov 2
CMH
Columbus
STL
St. Louis
$255 Roundtrip, found 4 hours ago
$255
Roundtrip
found 4 hours ago
Select United flight, departing Thu, Oct 29 from Columbus to St. Louis, returning Mon, Nov 2, priced at $255 found 4 hours ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $375
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $375

What you need to know for your flight from John Glenn Columbus Intl. to Lambert-St. Louis Intl.

Columbus (CMH) to St. Louis (STL) at a glance

Travel between Columbus (CMH) and St. Louis (STL) with a selection of airlines catering to this domestic short-haul route. You can evaluate options from both full-service and low-cost carriers to discover the best itinerary that aligns with your budget and schedule as you plan your visit to the iconic sights and vibrant neighborhoods of St. Louis. Here, you'll find essential information about flights from John Glenn Columbus International Airport (CMH) to Lambert-St. Louis International Airport (STL).

  • Fastest flight duration: around 1h 30m non-stop
  • Route distance: roughly 400 miles (645 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $90–$370, depending on seasonality and how far ahead you book

Flights from John Glenn Columbus International Airport (CMH) to Lambert-St. Louis International Airport (STL)

Based on the latest traveler bookings, here are the top airlines flying from Columbus to St. Louis, favored for both non-stop and one-stop flights. Many travelers opt for layovers at O'Hare International Airport (ORD) with a 1 hour 30 minute wait, Charlotte-Douglas International Airport (CLT) with a 55 minute layover, or Detroit Metropolitan Wayne County Airport (DTW) with a 1 hour layover. These options allow you to customize your itinerary by balancing price, total travel time, and cabin class for the best travel experience.

  • Southwest Airlines: This budget-friendly airline provides both non-stop and one-stop flights, with one-way ticket prices typically falling between $90 and $370. It dominates the route with about 61% of departures, and non-stop trips generally take around 1 hour and 30 minutes.
  • American Airlines: As a full-service airline, American Airlines offers one-stop flights, with one-way fares usually between $90 and $350. It accounts for about 20% of the departures on this route, with an in-flight duration of 3 hours and a total travel time of around 4 hours and 15 minutes, including layovers.
  • Delta: This full-service airline provides one-stop service, with one-way fares generally ranging from $95 to $420. Delta represents approximately 9% of the route's departures, featuring an in-flight duration of 3 hours and an overall journey time of approximately 4 hours and 15 minutes, factoring in layover times.
  • United: Another full-service option, United offers one-stop flights with one-way fares typically between $100 and $335. It also accounts for about 9% of departures on this route, with a flight time of 3 hours and a total travel duration of roughly 4 hours and 15 minutes, including layovers.
  • Frontier Airlines: As a low-cost carrier, Frontier provides one-stop service with one-way fares usually ranging from $95 to $150. This airline makes up around 1% of the departures on this route, with an in-flight time of 3 hours and a total travel time of about 4 hours and 15 minutes, including layovers.

Best time to fly from Columbus (CMH) to St. Louis (STL)

The most popular months for travelers flying from Columbus to St. Louis are March, April, and August, when peak temperatures in St. Louis reach up to 77°F in August. If you prefer quieter travel, consider July, the least busy time to visit with temperatures around 78.6°F and typically the lowest average one-way fare (around $190). Flight availability peaks in October and November, with approximately 12 flights per week, making it easier to find convenient departure times. January and December have the fewest flights, with approximately 9 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $190, roughly 12% cheaper than the yearly average.
  • More budget-friendly months to fly: August and June typically offer average one-way fares of around $192.
  • Most flight options: October and November have the highest number of flights from Columbus to St. Louis, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January31.6°F (-0.2°C)Average9$222
February34.9°F (1.6°C)Average11$230
March46.4°F (8.0°C)Slightly High10$226
April56.1°F (13.4°C)Slightly High10$221
May66.6°F (19.2°C)Slightly Low11$221
June76.1°F (24.5°C)Average10$192
July78.6°F (25.9°C)Slightly Low10$190
August77.0°F (25.0°C)Slightly High11$191
September70.9°F (21.6°C)Average11$218
October58.6°F (14.8°C)Average12$212
November46.2°F (7.9°C)Average12$227
December37.8°F (3.2°C)Slightly Low9$256

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Columbus (CMH) to St. Louis (STL)

  • Columbus to St. Louis (OSU-STL): Located approximately 11 miles from John Glenn Columbus International Airport (CMH), Ohio State University Airport (OSU) offers convenient access for travelers heading to St. Louis.
  • Columbus to St. Louis (LCK-STL): Rickenbacker International Airport (LCK) lies about 13 miles from John Glenn Columbus International Airport (CMH), providing another viable option for flights to St. Louis.
  • Columbus to St. Louis (CMH-CPS): St. Louis Downtown Airport (CPS) is roughly 16 miles distant from Lambert-St. Louis International Airport (STL), making it a practical choice for those flying from Columbus.

How to find the best prices for flights from Columbus (CMH) to St. Louis (STL)

Getting some of the best deals on flights from Columbus to St. Louis is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking at least two months in advance, although most travelers book between two to eight weeks ahead. Evening departures (6 PM to 12 AM) tend to offer lower prices, while morning flights (5 AM to 12 PM) are the most popular. Additionally, flying on Saturday generally provides cheaper rates, even though Friday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Lambert-St. Louis International Airport from John Glenn Columbus International Airport

St. Louis welcomes travelers from Columbus with a range of transport options based on price, convenience, and proximity. Here's how to reach St. Louis efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in St. Louis, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Lambert-St. Louis International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Lambert-St. Louis International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Lambert-St. Louis International Airport, Lambert Main Terminal Station, a metro station, is conveniently located just 0.1 miles away on foot, providing easy access for travelers.

Frequently asked questions

How much does a flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find cheap one-way flights from $115 and cheap return flights from $133 Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights typically cost between $131 and $562, and return flights often range between $284 and $905. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
August is the cheapest month to fly from Columbus, OH (CMH) to St. Louis, MO (STL), with average return fares around $265. This price is about 20% lower than the average throughout the year, as August typically sees a decrease in travel after the summer vacation season. Other affordable months to fly from Columbus to St. Louis include April and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter CMH to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Southwest Airlines is one of the cheapest airlines offering nonstop flights from Columbus, OH (CMH) to St. Louis, MO (STL), with round-trip tickets starting from around $176. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best airline to fly with from Columbus, OH (CMH) to St. Louis, MO (STL) will differ from traveler to traveler. If you like to fly early, WN offers early morning flights. If price is the most important factor, WN typically offers the lowest fares. WN offers the most daily flights from CMH to STL, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
For flights from Columbus to St. Louis, April and August are the best months to consider. You can find return flights for about $265, making it an affordable option. April offers a lovely spring atmosphere, while August allows you to enjoy summer activities in St. Louis.*Prices based on flights available on Expedia in the last year.
How many flights per day from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You can find approximately 2 nonstop flights per day from John Glenn Columbus Intl. (CMH) to Lambert-St. Louis Intl. (STL). For more options, look at flights that include layovers.
What is the earliest flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from Columbus (CMH-John Glenn Columbus Intl.) to St. Louis (STL-Lambert-St. Louis Intl.) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in February and March, giving you an early start to your journey. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
For flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), the most popular departure times are in the early morning, from 6am to 9am. About 29% of passengers prefer this time window. Many major carriers, including Delta Airlines, American Airlines, and United Airlines, offer flights during this window. This timing is popular because it allows travelers to arrive in St. Louis with plenty of time to enjoy the day.
How long does it take to fly from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Flying nonstop from CMH to STL takes around 1 hour 30 minutes, with the route covering approximately 409 miles. Flights with a layover typically take 5 hours longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
First class is available on flights from CMH to STL. First class cabins are available on:

  • American Airlines
  • United Airlines
  • Delta Air Lines

How do I earn miles on a Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from John Glenn Columbus Intl. (CMH)?
If you're planning to travel to St. Louis from John Glenn Columbus Intl. (CMH), you can fly into Lambert-St. Louis Intl. (STL) Some flights may connect through major hubs like Washington Dulles Intl. (IAD), Baltimore Washington Intl. Thurgood Marshall (BWI), Midway Intl. (MDW) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

0
Origin airport
John Glenn Columbus Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$133
Distance
408 mi

Book with confidence

Columbus to St. Louis Flights

The cheapest times to fly from Columbus to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to St. Louis are during the month of October. You can find some of the cheapest flights from Columbus to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbus to St. Louis

Sunday is one of the best days to book for cheap flights from Columbus to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbus to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbus to St. Louis Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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