$378 Cheap Flights from Istanbul (IST) to San Francisco (SFO)

View $378 flight on Thu, Mar 5, 2026Opens in a new window

Popular airlines from Istanbul Airport (IST) to San Francisco Intl. Airport (SFO)

Cheap Flights from Istanbul to San Francisco (IST-SFO)

Prices were available within the past 7 days and start at $378 for one-way flights and $624 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Tue, Dec 2 - Mon, Dec 8
IST
Istanbul
SFO
San Francisco
$624 Roundtrip, found 2 hours ago
$624
Roundtrip
found 2 hours ago
Select KLM flight, departing Tue, Dec 2 from Istanbul to San Francisco, returning Mon, Dec 8, priced at $624 found 2 hours ago
KLM
Fri, Feb 13 - Mon, Feb 23
IST
Istanbul
SFO
San Francisco
$624 Roundtrip, found 3 days ago
$624
Roundtrip
found 3 days ago
Select KLM flight, departing Fri, Feb 13 from Istanbul to San Francisco, returning Mon, Feb 23, priced at $624 found 3 days ago
KLM
Sun, Nov 9 - Tue, Nov 18
IST
Istanbul
SFO
San Francisco
$626 Roundtrip, found 4 days ago
$626
Roundtrip
found 4 days ago
Select KLM flight, departing Sun, Nov 9 from Istanbul to San Francisco, returning Tue, Nov 18, priced at $626 found 4 days ago
KLM
Thu, Nov 20 - Thu, Nov 27
IST
Istanbul
SFO
San Francisco
$628 Roundtrip, found 1 hour ago
$628
Roundtrip
found 1 hour ago
Select KLM flight, departing Thu, Nov 20 from Istanbul to San Francisco, returning Thu, Nov 27, priced at $628 found 1 hour ago
KLM
Tue, Dec 2 - Sun, Dec 7
IST
Istanbul
SFO
San Francisco
$630 Roundtrip, found 2 hours ago
$630
Roundtrip
found 2 hours ago
Select KLM flight, departing Tue, Dec 2 from Istanbul to San Francisco, returning Sun, Dec 7, priced at $630 found 2 hours ago
KLM
Fri, Feb 13 - Mon, Feb 23
IST
Istanbul
SFO
San Francisco
$630 Roundtrip, found 3 days ago
$630
Roundtrip
found 3 days ago
Select KLM flight, departing Fri, Feb 13 from Istanbul to San Francisco, returning Mon, Feb 23, priced at $630 found 3 days ago
Air France
Tue, Jan 27 - Tue, Feb 10
IST
Istanbul
SFO
San Francisco
$636 Roundtrip, found 3 days ago
$636
Roundtrip
found 3 days ago
Select Air France flight, departing Tue, Jan 27 from Istanbul to San Francisco, returning Tue, Feb 10, priced at $636 found 3 days ago
American Airlines
Sun, Nov 23 - Sat, Nov 29
IST
Istanbul
SFO
San Francisco
$637 Roundtrip, found 2 hours ago
$637
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sun, Nov 23 from Istanbul to San Francisco, returning Sat, Nov 29, priced at $637 found 2 hours ago
British Airways
Wed, Dec 24 - Sun, Jan 11
IST
Istanbul
SFO
San Francisco
$640 Roundtrip, found 4 hours ago
$640
Roundtrip
found 4 hours ago
Select British Airways flight, departing Wed, Dec 24 from Istanbul to San Francisco, returning Sun, Jan 11, priced at $640 found 4 hours ago
Air Canada
Thu, Dec 4 - Wed, Jan 14
IST
Istanbul
SFO
San Francisco
$648 Roundtrip, found 4 days ago
$648
Roundtrip
found 4 days ago
Select Air Canada flight, departing Thu, Dec 4 from Istanbul to San Francisco, returning Wed, Jan 14, priced at $648 found 4 days ago

Find the cheapest month to fly from Istanbul (IST) to San Francisco (SFO)

February is typically the cheapest month to fly

From $453 - $1,227 per traveler.

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to San Francisco Intl. SFO. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $685
SFO
San Francisco Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $685

Frequently asked questions

How much does a flight from Istanbul (IST) to San Francisco Intl. Airport (SFO) cost?
Grab a cheap one-way flight from $378 or cheap return flight from $624 from Istanbul (IST) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Istanbul (IST) to San Francisco Intl. Airport (SFO)?
Planning your getaway for December is a great way to save, as it's the cheapest month for flights between IST and SFO. You'll typically find the lowest fares during the off-season.
Which airlines fly direct from Istanbul (IST) to San Francisco Intl. Airport (SFO)?
You can't catch a direct flight from Istanbul (IST) to San Francisco Intl. Airport (SFO). However, you can seamlessly travel to San Francisco without any layovers by taking off from Ataturk Intl. Airport (IST).
What is the cheapest airline that flies from Istanbul (IST) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline that'll fly you from IST to SFO, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Istanbul (IST) to San Francisco Intl. Airport (SFO)?
You'll have to catch a flight with a layover if you're traveling from Istanbul (IST) to San Francisco Intl. Airport (SFO). There are no daily direct flights on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from IST to SFO?
Usually you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Istanbul (IST) to San Francisco Intl. Airport (SFO)?
Opt for a flight from Istanbul (IST) to San Francisco Intl. Airport (SFO) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Istanbul (IST) to San Francisco Intl. Airport (SFO) last-minute?
Booking your plane ticket from IST to SFO just before your trip is generally more expensive. But if you're flexible with your itinerary, you could snag a cheap last-minute fare.
Is it cheaper to book an IST to SFO flight and hotel package?
You'll generally save money by securing an IST to SFO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your ideal accommodations and flights, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Istanbul (IST) to San Francisco Intl. Airport (SFO)?
It's usually possible to reschedule or cancel your IST to SFO flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Istanbul
Destination airport
San Francisco Intl.
Airlines serving
Air Canada, Air France, American Airlines, British Airways, Delta, Emirates, Icelandair, KLM, Lufthansa, Qatar Airways, Scandinavian Airlines, Singapore Airlines, TAP Portugal, Turkish Airlines, United
Roundtrip price
$623
Distance
6690 mi
Average flight time
3 hours 57 mins

Book with confidence

Istanbul to San Francisco Flights

The cheapest times to fly from Istanbul to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Istanbul to San Francisco are during the month of December. You can find some of the cheapest flights from Istanbul to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Istanbul to San Francisco

Sunday is one of the best days to book for cheap flights from Istanbul to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Istanbul to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Istanbul to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $378 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Istanbul to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Istanbul to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Istanbul to San Francisco Flights

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*Available to One Key members.