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$76 Cheap Flights from Jacksonville (JAX) to St. Louis (STL)

View $76 flight on Tue, Dec 1, 2026Opens in a new window

Popular airlines from Jacksonville International Airport (JAX) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Jacksonville to St. Louis (JAX-STL)

Prices were available within the past 7 days and start at $76 for one-way flights and $141 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Tue, Oct 27 - Mon, Nov 2
JAX
Jacksonville
STL
St. Louis
$141 Roundtrip, found 12 hours ago
$141
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Tue, Oct 27 from Jacksonville to St. Louis, returning Mon, Nov 2, priced at $141 found 12 hours ago
Frontier Airlines
Sun, Nov 1 - Wed, Nov 4
JAX
Jacksonville
STL
St. Louis
$192 Roundtrip, found 12 hours ago
$192
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Sun, Nov 1 from Jacksonville to St. Louis, returning Wed, Nov 4, priced at $192 found 12 hours ago
Frontier Airlines
Thu, Dec 10 - Thu, Dec 17
JAX
Jacksonville
STL
St. Louis
$214 Roundtrip, found 23 hours ago
$214
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Thu, Dec 10 from Jacksonville to St. Louis, returning Thu, Dec 17, priced at $214 found 23 hours ago
Frontier Airlines
Thu, Dec 3 - Mon, Dec 7
JAX
Jacksonville
STL
St. Louis
$221 Roundtrip, found 13 hours ago
$221
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Thu, Dec 3 from Jacksonville to St. Louis, returning Mon, Dec 7, priced at $221 found 13 hours ago
Frontier Airlines
Sun, Nov 1 - Fri, Nov 6
JAX
Jacksonville
STL
St. Louis
$243 Roundtrip, found 12 hours ago
$243
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Sun, Nov 1 from Jacksonville to St. Louis, returning Fri, Nov 6, priced at $243 found 12 hours ago
United
Wed, Nov 11 - Thu, Nov 12
JAX
Jacksonville
STL
St. Louis
$270 Roundtrip, found 1 day ago
$270
Roundtrip
found 1 day ago
Select United flight, departing Wed, Nov 11 from Jacksonville to St. Louis, returning Thu, Nov 12, priced at $270 found 1 day ago
Southwest Airlines
Sat, Oct 24 - Mon, Nov 2
JAX
Jacksonville
STL
St. Louis
$275 Roundtrip, found 12 hours ago
$275
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Sat, Oct 24 from Jacksonville to St. Louis, returning Mon, Nov 2, priced at $275 found 12 hours ago
Delta
Thu, Oct 8 - Mon, Oct 12
JAX
Jacksonville
STL
St. Louis
$275 Roundtrip, found 3 hours ago
$275
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Oct 8 from Jacksonville to St. Louis, returning Mon, Oct 12, priced at $275 found 3 hours ago
American Airlines
Sat, Nov 7 - Sat, Nov 14
JAX
Jacksonville
STL
St. Louis
$275 Roundtrip, found 6 hours ago
$275
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Nov 7 from Jacksonville to St. Louis, returning Sat, Nov 14, priced at $275 found 6 hours ago
Frontier Airlines
Sun, Dec 6 - Wed, Dec 9
JAX
Jacksonville
STL
St. Louis
$275 Roundtrip, found 4 days ago
$275
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Dec 6 from Jacksonville to St. Louis, returning Wed, Dec 9, priced at $275 found 4 days ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $377
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $377

What you need to know for your flight from Jacksonville Intl. to Lambert-St. Louis Intl.

Jacksonville (JAX) to St. Louis (STL) at a glance

Travel from Jacksonville (JAX) to St. Louis (STL) with a selection of airlines operating this domestic short-haul route. Evaluate various options, including both full-service and budget-friendly carriers, to discover the itinerary that aligns with your travel plans, budget, and schedule. As you prepare to explore the iconic attractions and vibrant neighborhoods of St. Louis, gather essential information on flights from Jacksonville International Airport (JAX) to Lambert-St. Louis International Airport (STL).

  • Fastest flight duration: around 2h 15m non-stop
  • Route distance: roughly 800 miles (1,290 km)
  • Flights per week: around 15+ flights with multiple daily departures on average
  • Typical fares (one-way): economy tickets often range from $90–$405, depending on seasonality and how far ahead you book

Flights from Jacksonville International Airport (JAX) to Lambert-St. Louis International Airport (STL)

According to recent traveler bookings, here are the top airlines favored for flights from Jacksonville to St. Louis, featuring both non-stop and one-stop options. Popular layover airports include Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of around 1 hour and 30 minutes, Charlotte-Douglas International Airport (CLT) with about a 1-hour layover, and O'Hare International Airport (ORD) with an estimated layover of 1 hour and 15 minutes. This variety allows you to tailor your journey by comparing price, total travel time, and cabin class for the ideal itinerary.

  • Southwest Airlines: This budget-friendly airline provides both non-stop and one-stop options, with one-way fares usually falling between $90 and $405. It represents around 41% of the departures on this route, and a typical non-stop flight takes about 2 hours and 15 minutes.
  • American Airlines: As a full-service airline, American Airlines offers one-stop flights with one-way prices generally ranging from $100 to $350. It makes up approximately 29% of the flights on this route, featuring a flight duration of 3 hours and 30 minutes and a total travel time of about 4 hours and 45 minutes, including layover time.
  • Delta: Another full-service option, Delta provides one-stop service with one-way fares typically between $90 and $415. It accounts for roughly 24% of the departures on this route, with an in-flight time of 3 hours and 30 minutes and a total journey time of around 4 hours and 45 minutes, including any layovers.
  • United: United Airlines, also a full-service carrier, offers one-stop flights at one-way fares usually ranging from $105 to $415. This airline contributes to about 6% of the departures for this route, with an in-flight duration of 3 hours and 30 minutes and a total travel time of approximately 4 hours and 45 minutes, factoring in layovers.

Travelers have the option to enhance their journey from Jacksonville to St. Louis with upgraded flight choices. Delta provides both first class and premium economy cabins, while American Airlines and United both offer first class service for a more luxurious travel experience.

Best time to fly from Jacksonville (JAX) to St. Louis (STL)

The most popular months for travelers flying from Jacksonville to St. Louis are January, March, and April, when peak temperatures in St. Louis reach up to 56.1°F in April. If you prefer quieter travel, consider August, the least busy time to visit with temperatures around 77°F and typically the lowest average one-way fare (around $175). Flight availability peaks in March, with approximately 20 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 13 flights per week.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $175, roughly 11% cheaper than the yearly average.
  • More budget-friendly months to fly: July, June, and September typically offer average one-way fares of around $184.
  • Most flight options: March has the highest number of flights from Jacksonville to St. Louis, with approximately 20 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January31.6°F (-0.2°C)Slightly High13$206
February34.9°F (1.6°C)Average15$204
March46.4°F (8.0°C)Slightly High20$226
April56.1°F (13.4°C)Slightly High17$218
May66.6°F (19.2°C)Slightly Low14$203
June76.1°F (24.5°C)Average19$185
July78.6°F (25.9°C)Average17$182
August77.0°F (25.0°C)Slightly Low14$175
September70.9°F (21.6°C)Average15$186
October58.6°F (14.8°C)Average18$195
November46.2°F (7.9°C)Slightly Low18$204
December37.8°F (3.2°C)Average17$193

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Jacksonville (JAX) to St. Louis (STL)

  • Jacksonville to St. Louis (JAX-SUS): Spirit of St. Louis Airport (SUS) is located approximately 16 miles from Lambert-St. Louis International Airport (STL).
  • Jacksonville to St. Louis (JAX-CPS): St. Louis Downtown Airport (CPS) lies about 16 miles distant from Lambert-St. Louis International Airport (STL).

How to find the best prices for flights from Jacksonville (JAX) to St. Louis (STL)

Getting some of the best deals on flights from Jacksonville to St. Louis is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Evening departures (6 PM to 12 AM) often offer lower prices, while morning flights (5 AM to 12 PM) are the most popular. Additionally, flying on Thursday provides both better prices and is the favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Lambert-St. Louis International Airport from Jacksonville International Airport

St. Louis welcomes travelers from Jacksonville with a range of transport options based on price, convenience, and proximity. Here's how to reach St. Louis efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in St. Louis, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Lambert-St. Louis International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Lambert-St. Louis International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Lambert-St. Louis International Airport, Lambert Main Terminal Station, a metro station, is conveniently located just 0.1 miles away on foot, providing easy access to public transportation.

Frequently asked questions

How much does a flight from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find cheap one-way flights from $76 and cheap return flights from $141 Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights generally range between $158 and $622, and roundtrip flights usually range from $294 to $997. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
August is the cheapest month to fly from Jacksonville to St. Louis, with average return fares around $286. This is about 15% lower than the average price for the year, as summer travel tends to slow down. Other affordable months to fly from Jacksonville to St. Louis include April and October.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter JAX to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Southwest Airlines is one of the cheapest airlines offering nonstop flights from Jacksonville (JAX) to St. Louis (STL), with round-trip tickets starting from around $469. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best airline to fly with from Jacksonville, FL (JAX) to St. Louis, MO (STL) will differ from traveler to traveler. If you like to fly early, WN offers early morning flights. If price is the most important factor, WN typically offers the lowest fares. United offers the most daily flights from JAX to STL, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best time to fly from Jacksonville (JAX) to St. Louis (STL) is in August or October. You can expect return flights to be around $286, which is quite affordable. August is a popular month for travel, while October typically has pleasant weather, making it a great time to explore St. Louis.*Prices based on flights available on Expedia in the last year.
How many flights per day from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You can find approximately 1 nonstop flights per day from Jacksonville Intl. (JAX) to Lambert-St. Louis Intl. (STL). For more options, look at flights that include layovers.
What is the earliest flight from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from Jacksonville, FL (JAX) to St. Louis, MO (STL) usually departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in November and December, making it a convenient choice for holiday travel. An early flight helps you make the most of your day in St. Louis. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
For flights from Jacksonville International Airport (JAX) to Lambert-St. Louis International Airport (STL), the most popular departure times are in the morning, from 6am to 9am. This time window captures about 29% of total traffic. Many major carriers, including American Airlines, Delta Airlines, and Southwest Airlines, operate flights during this period. This timing is favored as it allows you to start your day in Jacksonville before heading off to your destination.
How long does it take to fly from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Flying nonstop from JAX to STL takes around 2 hours 20 minutes, with the route covering approximately 753 miles. Flights with a layover typically take 3 hours 10 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Select the "Business class" and "First class" filters when looking for JAX to STL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from Jacksonville Intl. (JAX)?
From Jacksonville Intl. (JAX), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Washington Dulles Intl. (IAD), George Bush Intercontinental (IAH), Liberty Intl. (EWR) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Jacksonville, FL (JAX-Jacksonville Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Jacksonville Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$141
Distance
753 mi
Average flight time
1 hour 30 mins

Book with confidence

Jacksonville to St. Louis Flights

The cheapest times to fly from Jacksonville to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Jacksonville to St. Louis are during the month of October. You can find some of the cheapest flights from Jacksonville to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Jacksonville to St. Louis

Sunday is one of the best days to book for cheap flights from Jacksonville to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Jacksonville to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Jacksonville to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $76 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Jacksonville to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Jacksonville to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Jacksonville to St. Louis Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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