$80 Cheap Flights from Jacksonville (JAX) to St. Louis (STL)

View $80 flight on Sat, Nov 8, 2025Opens in a new window

Popular airlines from Jacksonville International Airport (JAX) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Jacksonville to St. Louis (JAX-STL)

Prices were available within the past 7 days and start at $80 for one-way flights and $155 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Nov 14 - Mon, Nov 17
JAX
Jacksonville
STL
St. Louis
$155 Roundtrip, found 3 days ago
$155
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Nov 14 from Jacksonville to St. Louis, returning Mon, Nov 17, priced at $155 found 3 days ago
United
Mon, Jan 26 - Tue, Feb 3
JAX
Jacksonville
STL
St. Louis
$156 Roundtrip, found 3 days ago
$156
Roundtrip
found 3 days ago
Select United flight, departing Mon, Jan 26 from Jacksonville to St. Louis, returning Tue, Feb 3, priced at $156 found 3 days ago
American Airlines
Wed, Dec 17 - Tue, Dec 30
JAX
Jacksonville
STL
St. Louis
$169 Roundtrip, found 4 days ago
$169
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 17 from Jacksonville to St. Louis, returning Tue, Dec 30, priced at $169 found 4 days ago
Southwest Airlines
Wed, Dec 3 - Sat, Dec 6
JAX
Jacksonville
STL
St. Louis
$179 Roundtrip, found 6 days ago
$179
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Dec 3 from Jacksonville to St. Louis, returning Sat, Dec 6, priced at $179 found 6 days ago
Southwest Airlines
Wed, Dec 3 - Sat, Dec 6
JAX
Jacksonville
STL
St. Louis
$180 Roundtrip, found 6 days ago
$180
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Dec 3 from Jacksonville to St. Louis, returning Sat, Dec 6, priced at $180 found 6 days ago
American Airlines
Wed, Jan 7 - Mon, Jan 12
JAX
Jacksonville
STL
St. Louis
$184 Roundtrip, found 6 days ago
$184
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jan 7 from Jacksonville to St. Louis, returning Mon, Jan 12, priced at $184 found 6 days ago
United
Wed, Dec 3 - Sat, Dec 6
JAX
Jacksonville
STL
St. Louis
$185 Roundtrip, found 6 days ago
$185
Roundtrip
found 6 days ago
Select United flight, departing Wed, Dec 3 from Jacksonville to St. Louis, returning Sat, Dec 6, priced at $185 found 6 days ago
United
Fri, Nov 14 - Mon, Nov 17
JAX
Jacksonville
STL
St. Louis
$187 Roundtrip, found 3 days ago
$187
Roundtrip
found 3 days ago
Select United flight, departing Fri, Nov 14 from Jacksonville to St. Louis, returning Mon, Nov 17, priced at $187 found 3 days ago
United
Wed, Dec 3 - Sat, Dec 6
JAX
Jacksonville
STL
St. Louis
$188 Roundtrip, found 6 days ago
$188
Roundtrip
found 6 days ago
Select United flight, departing Wed, Dec 3 from Jacksonville to St. Louis, returning Sat, Dec 6, priced at $188 found 6 days ago
Delta
Thu, Nov 13 - Sat, Nov 15
JAX
Jacksonville
STL
St. Louis
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Nov 13 from Jacksonville to St. Louis, returning Sat, Nov 15, priced at $244 found 2 days ago

Find the cheapest month to fly from Jacksonville (JAX) to St. Louis (STL)

August is typically the cheapest month to fly

From $154 - $446 per traveler.

Frequently asked questions

How much does a flight from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $80 or cheap return flight from $155 from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
November is the most affordable month to fly from JAX to STL. Traveling during quieter months is often the key to finding a great deal.
Which airlines fly direct from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
If you're departing from Jacksonville Intl. Airport (JAX), you can jump on a nonstop flight to Lambert-St. Louis Intl. Airport (STL) with Southwest Airlines.
What is the cheapest airline that flies from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline that'll fly you from JAX to STL, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
On average, Jacksonville Intl. Airport (JAX) has 3 direct flights to Lambert-St. Louis Intl. Airport (STL) per week. For more options, take advantage of Expedia's filters to look for flights with one or more stops. Fit in a quick visit to another destination or just break up your journey.
What are the most popular departure times for flights from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
More travelers fly between JAX and STL at 11 AM than at any other time. Rather go when it's quieter? Consider flying outside peak hours and you could save on your fare as well.
What day of the week has the most flights from JAX to STL?
If you travel on a Friday, you'll get the greatest range of choices for flights from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL).
What is the earliest flight from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
Hop on the earliest flight at around 11:50AM UTC-5, heading out of Jacksonville Intl. Airport (JAX). You'll be in the air for about 2h 20m, arriving at Lambert-St. Louis Intl. Airport (STL) at approximately 1:10PM UTC-6.
How long does it take to fly from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
Flights from JAX to STL have an average travel time of 2 hours and 20 minutes. The total distance between the two is 750 mi.
What is the best time to fly from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
To arrive at Lambert-St. Louis Intl. Airport (STL) on schedule, pick a flight that leaves Jacksonville Intl. Airport (JAX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from Jacksonville Intl. Airport (JAX)?
Compare your flight options from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL). This is the only airport in St. Louis you can land at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Waiting until just before your departure to book a flight from JAX to STL often results in higher prices. While you might find some last-minute deals, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of getting a bargain.
Is it cheaper to book a JAX to STL flight and hotel package?
Compared with arranging hotels and flights separately, booking a JAX to STL flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place will take the hassle out of planning your trip. Just pick your flights and choose from our wide range of hotels, then customize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Jacksonville Intl. Airport (JAX) to Lambert-St. Louis Intl. Airport (STL)?
If you booked your JAX to STL flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

Travel information

Travel information

Origin airport
Jacksonville Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$154
Distance
753 mi
Average flight time
1 hour 53 mins

Book with confidence

Book with confidence

Jacksonville to St. Louis Flights

The cheapest times to fly from Jacksonville to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Jacksonville to St. Louis are during the month of November. You can find some of the cheapest flights from Jacksonville to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Jacksonville to St. Louis

Sunday is one of the best days to book for cheap flights from Jacksonville to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Jacksonville to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Jacksonville to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $80 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Jacksonville to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Jacksonville to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Jacksonville to St. Louis Flights

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