$110 Cheap Flights from Moline (MLI) to St. Louis (STL)

View $110 flight on Wed, Dec 24, 2025Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from Moline to St. Louis (MLI-STL)

Prices were available within the past 7 days and start at $110 for one-way flights and $219 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Oct 31 - Mon, Nov 3
MLI
Moline
STL
St. Louis
$219 Roundtrip, found 3 days ago
$219
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Oct 31 from Moline to St. Louis, returning Mon, Nov 3, priced at $219 found 3 days ago
United
Fri, Oct 17 - Fri, Oct 24
MLI
Moline
STL
St. Louis
$219 Roundtrip, found 4 days ago
$219
Roundtrip
found 4 days ago
Select United flight, departing Fri, Oct 17 from Moline to St. Louis, returning Fri, Oct 24, priced at $219 found 4 days ago
United
Fri, Oct 10 - Mon, Oct 13
MLI
Moline
STL
St. Louis
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 10 from Moline to St. Louis, returning Mon, Oct 13, priced at $229 found 1 day ago
American Airlines
Fri, Oct 3 - Sun, Oct 5
MLI
Moline
STL
St. Louis
$234 Roundtrip, found 6 days ago
$234
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Oct 3 from Moline to St. Louis, returning Sun, Oct 5, priced at $234 found 6 days ago
United
Fri, Oct 3 - Sat, Oct 4
MLI
Moline
STL
St. Louis
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 3 from Moline to St. Louis, returning Sat, Oct 4, priced at $239 found 1 day ago
United
Fri, Oct 17 - Fri, Oct 24
MLI
Moline
STL
St. Louis
$239 Roundtrip, found 4 days ago
$239
Roundtrip
found 4 days ago
Select United flight, departing Fri, Oct 17 from Moline to St. Louis, returning Fri, Oct 24, priced at $239 found 4 days ago
United
Fri, Oct 10 - Mon, Oct 13
MLI
Moline
STL
St. Louis
$245 Roundtrip, found 1 day ago
$245
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 10 from Moline to St. Louis, returning Mon, Oct 13, priced at $245 found 1 day ago
American Airlines
Tue, Sep 30 - Wed, Oct 8
MLI
Moline
STL
St. Louis
$249 Roundtrip, found 16 hours ago
$249
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Tue, Sep 30 from Moline to St. Louis, returning Wed, Oct 8, priced at $249 found 16 hours ago
United
Fri, Oct 3 - Sun, Oct 5
MLI
Moline
STL
St. Louis
$253 Roundtrip, found 6 days ago
$253
Roundtrip
found 6 days ago
Select United flight, departing Fri, Oct 3 from Moline to St. Louis, returning Sun, Oct 5, priced at $253 found 6 days ago
Delta
Fri, Nov 7 - Tue, Nov 11
MLI
Moline
STL
St. Louis
$671 Roundtrip, found 3 days ago
$671
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Nov 7 from Moline to St. Louis, returning Tue, Nov 11, priced at $671 found 3 days ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $420
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $420

Frequently asked questions

How much does a flight from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL) cost?
Snag a cheap one-way flight from $110 or cheap return flight from $219 from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL)?
October is the most affordable month to fly from MLI to STL. Planning your trip for the off-season is often the key to finding better fares.
Which airlines fly direct from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL)?
While Moline, IL (MLI-Quad City Intl.) doesn't offer any direct flights to Lambert-St. Louis Intl. Airport (STL), other airports have nonstop options. Leaving from Southeast Iowa Regional Airport (BRL) will get you to St. Louis without any layovers.
What is the cheapest airline that flies from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MLI to STL flight.
How many flights per day from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL)?
There aren't any daily nonstop flights departing from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from MLI to STL?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary based on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL)?
Opt for a flight from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL) that leaves before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Waiting until just before your departure to book a ticket from MLI to STL generally means paying more. Although you may find some last-minute offers, they're not always guaranteed. Be flexible with your travel plans for a better chance of getting a bargain.
Is it cheaper to book a MLI to STL flight and hotel package?
Booking a MLI to STL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our wide range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quad City Intl. Airport (MLI) to Lambert-St. Louis Intl. Airport (STL)?
Typically, it's possible to reschedule or cancel your MLI to STL flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Quad City Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$218
Distance
187 mi

Book with confidence

Book with confidence

Moline to St. Louis Flights

The cheapest times to fly from Moline to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to St. Louis are during the month of October. You can find some of the cheapest flights from Moline to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Moline to St. Louis

Sunday is one of the best days to book for cheap flights from Moline to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Moline to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $110 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Moline to St. Louis Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.