$179 Cheap Flights from Missoula (MSO) to St. Louis (STL)

View $179 flight on Mon, Mar 2, 2026Opens in a new window

Popular airlines from Missoula Intl. Airport (MSO) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from Missoula to St. Louis (MSO-STL)

Prices were available within the past 7 days and start at $179 for one-way flights and $362 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hawaiian Airlines
Tue, Jan 13 - Tue, Jan 20
MSO
Missoula
STL
St. Louis
$362 Roundtrip, found 21 hours ago
$362
Roundtrip
found 21 hours ago
Select Hawaiian Airlines flight, departing Tue, Jan 13 from Missoula to St. Louis, returning Tue, Jan 20, priced at $362 found 21 hours ago
Delta
Wed, Jan 21 - Wed, Jan 21
MSO
Missoula
STL
St. Louis
$365 Roundtrip, found 6 days ago
$365
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Jan 21 from Missoula to St. Louis, returning Wed, Jan 21, priced at $365 found 6 days ago
Hawaiian Airlines
Tue, Jan 13 - Thu, Jan 22
MSO
Missoula
STL
St. Louis
$367 Roundtrip, found 21 hours ago
$367
Roundtrip
found 21 hours ago
Select Hawaiian Airlines flight, departing Tue, Jan 13 from Missoula to St. Louis, returning Thu, Jan 22, priced at $367 found 21 hours ago
Alaska Airlines
Wed, Jan 14 - Tue, Jan 20
MSO
Missoula
STL
St. Louis
$371 Roundtrip, found 21 hours ago
$371
Roundtrip
found 21 hours ago
Select Alaska Airlines flight, departing Wed, Jan 14 from Missoula to St. Louis, returning Tue, Jan 20, priced at $371 found 21 hours ago
American Airlines
Fri, Jan 16 - Mon, Jan 19
MSO
Missoula
STL
St. Louis
$371 Roundtrip, found 21 hours ago
$371
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Fri, Jan 16 from Missoula to St. Louis, returning Mon, Jan 19, priced at $371 found 21 hours ago
United
Fri, Jan 16 - Mon, Jan 19
MSO
Missoula
STL
St. Louis
$371 Roundtrip, found 21 hours ago
$371
Roundtrip
found 21 hours ago
Select United flight, departing Fri, Jan 16 from Missoula to St. Louis, returning Mon, Jan 19, priced at $371 found 21 hours ago
Alaska Airlines
Thu, Jan 8 - Wed, Jan 14
MSO
Missoula
STL
St. Louis
$372 Roundtrip, found 3 days ago
$372
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Thu, Jan 8 from Missoula to St. Louis, returning Wed, Jan 14, priced at $372 found 3 days ago
Hawaiian Airlines
Sat, Jan 17 - Tue, Jan 20
MSO
Missoula
STL
St. Louis
$372 Roundtrip, found 21 hours ago
$372
Roundtrip
found 21 hours ago
Select Hawaiian Airlines flight, departing Sat, Jan 17 from Missoula to St. Louis, returning Tue, Jan 20, priced at $372 found 21 hours ago
American Airlines
Tue, Jan 20 - Wed, Jan 21
MSO
Missoula
STL
St. Louis
$374 Roundtrip, found 6 days ago
$374
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jan 20 from Missoula to St. Louis, returning Wed, Jan 21, priced at $374 found 6 days ago
American Airlines
Tue, Jan 20 - Wed, Jan 21
MSO
Missoula
STL
St. Louis
$374 Roundtrip, found 6 days ago
$374
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jan 20 from Missoula to St. Louis, returning Wed, Jan 21, priced at $374 found 6 days ago

Find the cheapest month to fly from Missoula (MSO) to St. Louis (STL)

June is typically the cheapest month to fly

From $271 - $758 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $411
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $411

Frequently asked questions

How much does a flight from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL) cost?
Get a cheap one-way flight from $179 or cheap return flight from $362 from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL)?
Traveling in January can help you save, as it's the cheapest month for flights between MSO and STL. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline that'll fly you from MSO to STL, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL)?
There are no daily direct flights available from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL). But you can opt for flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from MSO to STL?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL)?
To touch down at Lambert-St. Louis Intl. Airport (STL) without delays, select a flight that takes off from Missoula Intl. Airport (MSO) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your plane ticket from MSO to STL shortly before your getaway is typically more expensive. However, if you're flexible with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a MSO to STL flight and hotel package?
You'll typically save money by securing a MSO to STL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After choosing your ideal accommodations and flights, you can add extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Missoula Intl. Airport (MSO) to Lambert-St. Louis Intl. Airport (STL)?
In most instances, you can cancel or reschedule your MSO to STL flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you want further information, visit our Customer Service portal.

Travel information

Origin airport
Missoula Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Hawaiian Airlines, United
Roundtrip price
$362
Distance
1320 mi

Book with confidence

Missoula to St. Louis Flights

The cheapest times to fly from Missoula to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Missoula to St. Louis are during the month of January. You can find some of the cheapest flights from Missoula to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Missoula to St. Louis

Sunday is one of the best days to book for cheap flights from Missoula to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Missoula to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Missoula to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $179 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Missoula to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Missoula to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Missoula to St. Louis Flights

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*Available to One Key members.