$59 Cheap Flights from Minneapolis (MSP) to Knoxville (TYS)

View $59 flight on Thu, Nov 13, 2025Opens in a new window

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)

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Cheap Flights from Minneapolis to Knoxville (MSP-TYS)

Prices were available within the past 7 days and start at $59 for one-way flights and $191 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Oct 23 - Mon, Oct 27
MSP
Minneapolis
TYS
Knoxville
$191 Roundtrip, found 3 hours ago
$191
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Oct 23 from Minneapolis to Knoxville, returning Mon, Oct 27, priced at $191 found 3 hours ago
Frontier Airlines
Sun, Nov 2 - Thu, Nov 6
MSP
Minneapolis
TYS
Knoxville
$201 Roundtrip, found 4 hours ago
$201
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sun, Nov 2 from Minneapolis to Knoxville, returning Thu, Nov 6, priced at $201 found 4 hours ago
Frontier Airlines
Thu, Oct 30 - Thu, Nov 13
MSP
Minneapolis
TYS
Knoxville
$234 Roundtrip, found 13 hours ago
$234
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Thu, Oct 30 from Minneapolis to Knoxville, returning Thu, Nov 13, priced at $234 found 13 hours ago
Frontier Airlines
Thu, Oct 23 - Mon, Oct 27
MSP
Minneapolis
TYS
Knoxville
$249 Roundtrip, found 3 hours ago
$249
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Oct 23 from Minneapolis to Knoxville, returning Mon, Oct 27, priced at $249 found 3 hours ago
American Airlines
Mon, Nov 24 - Thu, Nov 27
MSP
Minneapolis
TYS
Knoxville
$269 Roundtrip, found 14 hours ago
$269
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Nov 24 from Minneapolis to Knoxville, returning Thu, Nov 27, priced at $269 found 14 hours ago
Frontier Airlines
Thu, Nov 6 - Sun, Nov 9
MSP
Minneapolis
TYS
Knoxville
$274 Roundtrip, found 1 hour ago
$274
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Minneapolis to Knoxville, returning Sun, Nov 9, priced at $274 found 1 hour ago
American Airlines
Mon, Nov 24 - Thu, Nov 27
MSP
Minneapolis
TYS
Knoxville
$294 Roundtrip, found 14 hours ago
$294
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Nov 24 from Minneapolis to Knoxville, returning Thu, Nov 27, priced at $294 found 14 hours ago
Delta
Fri, Dec 5 - Tue, Dec 9
MSP
Minneapolis
TYS
Knoxville
$299 Roundtrip, found 2 hours ago
$299
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Dec 5 from Minneapolis to Knoxville, returning Tue, Dec 9, priced at $299 found 2 hours ago
United
Sat, Feb 21 - Sun, Feb 22
MSP
Minneapolis
TYS
Knoxville
$314 Roundtrip, found 4 days ago
$314
Roundtrip
found 4 days ago
Select United flight, departing Sat, Feb 21 from Minneapolis to Knoxville, returning Sun, Feb 22, priced at $314 found 4 days ago
Southwest Airlines
Wed, May 20 - Tue, May 26
MSP
Minneapolis
TYS
Knoxville
$319 Roundtrip, found 3 hours ago
$319
Roundtrip
found 3 hours ago
Select Southwest Airlines flight, departing Wed, May 20 from Minneapolis to Knoxville, returning Tue, May 26, priced at $319 found 3 hours ago

Find the cheapest month to fly from Minneapolis (MSP) to Knoxville (TYS)

January is typically the cheapest month to fly

From $158 - $598 per traveler.

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $449
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $449

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) cost?
Get a cheap one-way flight from $59 or cheap return flight from $191 from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
Traveling in October is a good way to save, as it's the cheapest month for flights between MSP and TYS. You'll usually find the lowest prices during the off-season.
Which airlines fly direct from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
Take a nonstop flight with Delta Air Lines and fly straight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS).
What is the cheapest airline that flies from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MSP to TYS flight.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
On average, there are 6 direct flights taking off from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) each week. If you don't find one that fits your schedule, consider taking a flight that includes a layover. Filter your search results on Expedia to include one or more stops and choose the next best option.
What are the most popular departure times for flights from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
More travelers fly between MSP and TYS at 7 PM than at any other point in the day. Prefer a quieter experience? Consider flying outside peak hours and it's possible you'll save on your fare as well.
What day of the week has the most flights from MSP to TYS?
If you travel on a Friday, you'll get the largest range of options for flights from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS).
What is the earliest flight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
The earliest flight departing from Minneapolis - St. Paul Intl. Airport (MSP) is at around 7:50PM UTC-6. Hop on this flight and you'll reach McGhee Tyson Airport (TYS) at approximately 11:04PM UTC-5. The entire trip takes 2h 14m.
How long does it take to fly from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
Flights from MSP to TYS have an average travel time of 2 hours and 14 minutes. The distance between these two airports is 790 mi.
What airline has the least delays from MSP to TYS?
Delta Air Lines has the best performance for on-time direct flights from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS), with an on-time score of 85%. Use the Expedia App to look up your flight schedule before you take off and receive notifications about any changes.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
To avoid possible delays on the Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Knoxville from Minneapolis - St. Paul Intl. Airport (MSP)?
Explore your flight options from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS). This is the only airport in Knoxville you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) last-minute?
Booking your flight from MSP to TYS shortly before your journey is usually more expensive. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a MSP to TYS flight and hotel package?
Compared with arranging flights and hotels separately, booking a MSP to TYS flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one place will take the stress out of planning your trip. Just pick your flights and choose from our extensive range of stays, then personalize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
In most cases, you can reschedule or cancel your MSP to TYS flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you need more information, visit our Customer Service portal.

Travel information

Origin airport
Minneapolis - St. Paul Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$191
Distance
792 mi
Average flight time
2 hours 10 mins

Book with confidence

Minneapolis to Knoxville Flights

The cheapest times to fly from Minneapolis to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Knoxville are during the month of October. You can find some of the cheapest flights from Minneapolis to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Minneapolis to Knoxville

Sunday is one of the best days to book for cheap flights from Minneapolis to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Minneapolis to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $59 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Minneapolis to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Minneapolis to Knoxville Flights

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*Available to One Key members.