Cheap Flights from Palo Alto (PAO) to St. Louis (STL)

Popular airlines from Palo Alto, CA (PAO-Santa Clara County) to St. Louis Lambert Intl. Airport (STL)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Frequently asked questions

How much does a flight from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL) cost?
Secure a cheap one-way flight or cheap return flight from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL)?
The cheapest month to fly from PAO to STL is , when there's less demand. Off-peak months are usually when airlines offer lower prices between these airports.
Which airlines fly direct from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL)?
There are no direct routes from Palo Alto, CA (PAO-Santa Clara County) to Lambert-St. Louis Intl. Airport (STL). However, you'll find other airports with nonstop flights. Hop on your plane at San Francisco Intl. Airport (SFO) and travel straight to St. Louis without layovers.
What is the cheapest airline that flies from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest PAO to STL flight.
How many flights per day from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL)?
There are no daily nonstop flights from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from PAO to STL?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL)?
To avoid potential delays on the Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL) route, travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your flight from PAO to STL shortly before your getaway is typically more expensive. However, if there's some wiggle room with your departure times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a PAO to STL flight and hotel package?
Securing a PAO to STL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our wide range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Santa Clara County Airport (PAO) to Lambert-St. Louis Intl. Airport (STL)?
Typically, it's possible to reschedule or cancel your PAO to STL flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Santa Clara County
Destination airport
Lambert-St. Louis Intl.
Distance
1719 mi

Book with confidence

Palo Alto to St. Louis Flights

The cheapest times to fly from Palo Alto to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Palo Alto to St. Louis are during the month of . You can find some of the cheapest flights from Palo Alto to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Palo Alto to St. Louis

Sunday is one of the best days to book for cheap flights from Palo Alto to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Palo Alto to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Palo Alto to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Palo Alto to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Palo Alto to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Palo Alto to St. Louis Flights

Explore a world of travel with Expedia

*Available to One Key members.