$144 Cheap Flights from San Francisco (SFO) to St. Louis (STL)

View $144 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from San Francisco to St. Louis (SFO-STL)

Prices were available within the past 7 days and start at $144 for one-way flights and $205 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Aug 27 - Thu, Sep 4
SFO
San Francisco
STL
St. Louis
$205 Roundtrip, found 5 days ago
$205
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Aug 27 from San Francisco to St. Louis, returning Thu, Sep 4, priced at $205 found 5 days ago
Frontier Airlines
Wed, Sep 3 - Mon, Sep 8
SFO
San Francisco
STL
St. Louis
$210 Roundtrip, found 4 days ago
$210
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Sep 3 from San Francisco to St. Louis, returning Mon, Sep 8, priced at $210 found 4 days ago
Frontier Airlines
Mon, Sep 8 - Thu, Sep 11
SFO
San Francisco
STL
St. Louis
$215 Roundtrip, found 4 days ago
$215
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Sep 8 from San Francisco to St. Louis, returning Thu, Sep 11, priced at $215 found 4 days ago
Frontier Airlines
Wed, Aug 27 - Sat, Aug 30
SFO
San Francisco
STL
St. Louis
$220 Roundtrip, found 5 days ago
$220
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Aug 27 from San Francisco to St. Louis, returning Sat, Aug 30, priced at $220 found 5 days ago
Frontier Airlines
Wed, Sep 3 - Sat, Sep 6
SFO
San Francisco
STL
St. Louis
$225 Roundtrip, found 4 days ago
$225
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Sep 3 from San Francisco to St. Louis, returning Sat, Sep 6, priced at $225 found 4 days ago
Frontier Airlines
Wed, Sep 3 - Sun, Sep 7
SFO
San Francisco
STL
St. Louis
$240 Roundtrip, found 4 days ago
$240
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Sep 3 from San Francisco to St. Louis, returning Sun, Sep 7, priced at $240 found 4 days ago
American Airlines
Fri, Sep 5 - Mon, Sep 15
SFO
San Francisco
STL
St. Louis
$262 Roundtrip, found 1 day ago
$262
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 5 from San Francisco to St. Louis, returning Mon, Sep 15, priced at $262 found 1 day ago
United
Wed, Jul 30 - Wed, Aug 6
SFO
San Francisco
STL
St. Louis
$293 Roundtrip, found 23 hours ago
$293
Roundtrip
found 23 hours ago
Select United flight, departing Wed, Jul 30 from San Francisco to St. Louis, returning Wed, Aug 6, priced at $293 found 23 hours ago
Southwest Airlines
Wed, Aug 20 - Sat, Aug 23
SFO
San Francisco
STL
St. Louis
$298 Roundtrip, found 20 hours ago
$298
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Wed, Aug 20 from San Francisco to St. Louis, returning Sat, Aug 23, priced at $298 found 20 hours ago
Hawaiian Airlines
Fri, Sep 5 - Tue, Sep 9
SFO
San Francisco
STL
St. Louis
$343 Roundtrip, found 4 days ago
$343
Roundtrip
found 4 days ago
Select Hawaiian Airlines flight, departing Fri, Sep 5 from San Francisco to St. Louis, returning Tue, Sep 9, priced at $343 found 4 days ago

Find the cheapest month to fly from San Francisco (SFO) to St. Louis (STL)

September is typically the cheapest month to fly

From $118 - $377 per traveler.

Graph displaying average flight prices per month

Flights from San Francisco (SFO) to St. Louis (STL)
Origin airport
San Francisco Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Southwest Airlines, Sun Country Airlines, United
Roundtrip price
$205
Distance
1731 mi
Average flight time
7 hours 12 mins

San Francisco to St. Louis Flights

The cheapest times to fly from San Francisco to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to St. Louis are during the month of August. You can find some of the cheapest flights from San Francisco to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to St. Louis

Sunday is one of the best days to book for cheap flights from San Francisco to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $144 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL) cost?
You can land affordable return tickets from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL) starting from $299. Book a seat and get ready to go. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a United flight leaving SFO on July 20 2025 and touching down at STL. The price was last updated on June 30 2025 and has not changed since.
What is the cheapest month to fly from SFO to STL?
The cheapest flights from SFO to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
Board a direct flight with United Airlines and go straight from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL).
What is the cheapest airline that flies from SFO to STL?
With prices as low as $147 for a one-way journey from SFO to STL, Southwest Airlines is currently the cheapest airline on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from SFO on September 23 2025. Prices were last updated on June 30 2025 and have not changed since.
How many flights per day from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
On average, there's only 1 nonstop flight operating from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL) every day. If this doesn't work for you, consider flights with layovers. Just customize your search on Expedia to include one or two stops to find the next best option.
What are the most popular departure times for flights from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
Flights between SFO and STL are their busiest at 10 AM. If you'd like a more relaxed trip and possibly cheaper tickets, choose a departure that's outside typical rush times.
What day of the week has the most flights from SFO to STL?
If you jet off on a Friday, you'll get the biggest range of options for flights from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL).
What is the earliest flight from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
The first flight of the day leaving San Francisco Intl. Airport (SFO) is at around 10:05AM UTC-8. Board this plane and you'll touch down at Lambert-St. Louis Intl. Airport (STL) at approximately 3:55PM UTC-6. The total travel time is 3h 50m.
How long does it take to fly from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
The average flight duration from SFO to STL is 3 hours and 54 minutes, covering a total distance of 1,750 mi.
What airline has the least delays from SFO to STL?
With 84% of flights generally landing on time, Southwest Airlines has the best on-time performance for nonstop flights from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL). To check your flight status and receive notifications about any changes, head to the Expedia App.
What is the best time to fly from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
Select a flight from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from San Francisco Intl. Airport (SFO)?
Compare your flight options from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL). This is the only airport in St. Louis you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Holding off until just before your departure to book a ticket from SFO to STL often results in higher prices. Although you may find some last-minute offers, they aren't always guaranteed. Be flexible with your itinerary for a better chance of landing a bargain.
Is it cheaper to book a SFO to STL flight and hotel package?
Booking a SFO to STL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our impressive range of accommodations and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to Lambert-St. Louis Intl. Airport (STL)?
Typically, it's possible to cancel or reschedule your SFO to STL flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.