$499 Cheap Flights from Palermo (PMO) to St. Louis (STL)

View $499 flight on Tue, May 19, 2026Opens in a new window

Popular airlines from Punta Raisi Airport (PMO) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Palermo to St. Louis (PMO-STL)

Prices were available within the past 7 days and start at $499 for one-way flights and $1,180 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,180 Roundtrip, found 4 days ago
$1,180
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,180 found 4 days ago
Lufthansa
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,221 Roundtrip, found 4 days ago
$1,221
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,221 found 4 days ago
ITA Airways
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,238 Roundtrip, found 4 days ago
$1,238
Roundtrip
found 4 days ago
Select ITA Airways flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,238 found 4 days ago
Swiss International Air Lines
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,241 Roundtrip, found 4 days ago
$1,241
Roundtrip
found 4 days ago
Select Swiss International Air Lines flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,241 found 4 days ago
Swiss International Air Lines
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,249 Roundtrip, found 4 days ago
$1,249
Roundtrip
found 4 days ago
Select Swiss International Air Lines flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,249 found 4 days ago
Swiss International Air Lines
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,282 Roundtrip, found 4 days ago
$1,282
Roundtrip
found 4 days ago
Select Swiss International Air Lines flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,282 found 4 days ago
British Airways
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,324 Roundtrip, found 4 days ago
$1,324
Roundtrip
found 4 days ago
Select British Airways flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,324 found 4 days ago
Lufthansa
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,337 Roundtrip, found 4 days ago
$1,337
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,337 found 4 days ago
Lufthansa
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,348 Roundtrip, found 4 days ago
$1,348
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,348 found 4 days ago
United
Sun, Jun 28 - Wed, Jul 15
PMO
Palermo
STL
St. Louis
$1,408 Roundtrip, found 4 days ago
$1,408
Roundtrip
found 4 days ago
Select United flight, departing Sun, Jun 28 from Palermo to St. Louis, returning Wed, Jul 15, priced at $1,408 found 4 days ago

Frequently asked questions

How much does a flight from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL) cost?
Lock in a cheap one-way flight from $499 or cheap return flight from $1,180 from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL)?
June is the least expensive month to fly from PMO to STL. Traveling during quieter months is often the key to finding better deals on flights.
What is the cheapest airline that flies from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from PMO to STL. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL)?
Nonstop flights from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PMO to STL?
Generally you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL)?
Opt for a flight from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your ticket from PMO to STL right before your journey is generally more expensive. However, if you're flexible with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a PMO to STL flight and hotel package?
Opting for a PMO to STL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our impressive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Punta Raisi Airport (PMO) to Lambert-St. Louis Intl. Airport (STL)?
If you booked your PMO to STL flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more information.

Travel information

Origin airport
Punta Raisi
Destination airport
Lambert-St. Louis Intl.
Roundtrip price
$1,179
Distance
5242 mi

Book with confidence

Palermo to St. Louis Flights

The cheapest times to fly from Palermo to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Palermo to St. Louis are during the month of June. You can find some of the cheapest flights from Palermo to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Palermo to St. Louis

Sunday is one of the best days to book for cheap flights from Palermo to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Palermo to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Palermo to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $499 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Palermo to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Palermo to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Palermo to St. Louis Flights

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*Available to One Key members.