$568 Cheap Flights from Prague (PRG) to St. Louis (STL)

View $568 flight on Sun, Jun 21, 2026Opens in a new window

Popular airlines from Vaclav Havel Airport (PRG) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Prague to St. Louis (PRG-STL)

Prices were available within the past 7 days and start at $568 for one-way flights and $917 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Wed, Nov 12 - Wed, Nov 26
PRG
Prague
STL
St. Louis
$917 Roundtrip, found 3 days ago
$917
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Wed, Nov 12 from Prague to St. Louis, returning Wed, Nov 26, priced at $917 found 3 days ago
Lufthansa
Fri, Nov 7 - Mon, Dec 1
PRG
Prague
STL
St. Louis
$917 Roundtrip, found 2 days ago
$917
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Fri, Nov 7 from Prague to St. Louis, returning Mon, Dec 1, priced at $917 found 2 days ago
Lufthansa
Fri, Nov 7 - Fri, Feb 20
PRG
Prague
STL
St. Louis
$919 Roundtrip, found 2 days ago
$919
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Fri, Nov 7 from Prague to St. Louis, returning Fri, Feb 20, priced at $919 found 2 days ago
Lufthansa
Fri, Nov 7 - Mon, Dec 1
PRG
Prague
STL
St. Louis
$920 Roundtrip, found 2 days ago
$920
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Fri, Nov 7 from Prague to St. Louis, returning Mon, Dec 1, priced at $920 found 2 days ago
Lufthansa
Wed, Nov 12 - Tue, Nov 25
PRG
Prague
STL
St. Louis
$921 Roundtrip, found 3 days ago
$921
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Wed, Nov 12 from Prague to St. Louis, returning Tue, Nov 25, priced at $921 found 3 days ago
Lufthansa
Fri, Nov 7 - Fri, Feb 20
PRG
Prague
STL
St. Louis
$922 Roundtrip, found 2 days ago
$922
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Fri, Nov 7 from Prague to St. Louis, returning Fri, Feb 20, priced at $922 found 2 days ago
Air Canada
Wed, Nov 12 - Mon, Nov 24
PRG
Prague
STL
St. Louis
$925 Roundtrip, found 4 days ago
$925
Roundtrip
found 4 days ago
Select Air Canada flight, departing Wed, Nov 12 from Prague to St. Louis, returning Mon, Nov 24, priced at $925 found 4 days ago
Air Dolomiti
Thu, Nov 13 - Tue, Nov 25
PRG
Prague
STL
St. Louis
$937 Roundtrip, found 5 days ago
$937
Roundtrip
found 5 days ago
Select Air Dolomiti flight, departing Thu, Nov 13 from Prague to St. Louis, returning Tue, Nov 25, priced at $937 found 5 days ago
Austrian Airlines
Fri, Nov 7 - Fri, Nov 14
PRG
Prague
STL
St. Louis
$946 Roundtrip, found 2 days ago
$946
Roundtrip
found 2 days ago
Select Austrian Airlines flight, departing Fri, Nov 7 from Prague to St. Louis, returning Fri, Nov 14, priced at $946 found 2 days ago
United
Fri, Nov 7 - Mon, Nov 10
PRG
Prague
STL
St. Louis
$952 Roundtrip, found 1 day ago
$952
Roundtrip
found 1 day ago
Select United flight, departing Fri, Nov 7 from Prague to St. Louis, returning Mon, Nov 10, priced at $952 found 1 day ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $927
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $927

Frequently asked questions

How much does a flight from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL) cost?
Lock in a cheap one-way flight from $568 or cheap return flight from $917 from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL)?
The cheapest month to fly from PRG to STL is November, when there's less demand. Off-peak season is typically when better flight deals are available between these airports.
What is the cheapest airline that flies from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll fly you from PRG to STL. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL)?
Direct flights from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PRG to STL?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can vary based on a range of factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL)?
Book a flight from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your flight from PRG to STL right before your getaway is typically more expensive. But if you're flexible with your departure dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a PRG to STL flight and hotel package?
Compared with arranging flights and hotels separately, booking a PRG to STL flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one convenient place will take the hassle out of planning your trip. Simply secure your flights and select from our extensive range of stays, then tailor your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Vaclav Havel Airport (PRG) to Lambert-St. Louis Intl. Airport (STL)?
Typically, you can cancel or reschedule your PRG to STL flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want more information, visit our Customer Service portal.

Travel information

Origin airport
Vaclav Havel
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Austrian Airlines, British Airways, Delta, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$916
Distance
4786 mi

Book with confidence

Prague to St. Louis Flights

The cheapest times to fly from Prague to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Prague to St. Louis are during the month of November. You can find some of the cheapest flights from Prague to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Prague to St. Louis

Sunday is one of the best days to book for cheap flights from Prague to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Prague to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Prague to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $568 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Prague to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Prague to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Prague to St. Louis Flights

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*Available to One Key members.