$498 Cheap Flights from Pisa (PSA) to St. Louis (STL)

View $498 flight on Sat, Nov 15, 2025Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Pisa to St. Louis (PSA-STL)

Prices were available within the past 7 days and start at $498 for one-way flights and $764 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$764 Roundtrip, found 6 days ago
$764
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $764 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$770 Roundtrip, found 6 days ago
$770
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $770 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$770 Roundtrip, found 6 days ago
$770
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $770 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$805 Roundtrip, found 6 days ago
$805
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $805 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$811 Roundtrip, found 6 days ago
$811
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $811 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$811 Roundtrip, found 6 days ago
$811
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $811 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$846 Roundtrip, found 6 days ago
$846
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $846 found 6 days ago
British Airways
Thu, Feb 12 - Sun, Feb 15
PSA
Pisa
STL
St. Louis
$922 Roundtrip, found 6 days ago
$922
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Feb 12 from Pisa to St. Louis, returning Sun, Feb 15, priced at $922 found 6 days ago
Lufthansa
Fri, Jul 24 - Sat, Aug 8
PSA
Pisa
STL
St. Louis
$1,082 Roundtrip, found 6 days ago
$1,082
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Fri, Jul 24 from Pisa to St. Louis, returning Sat, Aug 8, priced at $1,082 found 6 days ago
Scandinavian Airlines
Fri, Jul 24 - Sat, Aug 8
PSA
Pisa
STL
St. Louis
$1,369 Roundtrip, found 6 days ago
$1,369
Roundtrip
found 6 days ago
Select Scandinavian Airlines flight, departing Fri, Jul 24 from Pisa to St. Louis, returning Sat, Aug 8, priced at $1,369 found 6 days ago

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL) cost?
Lock in a cheap one-way flight from $498 or cheap return flight from $764 from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL)?
February is the cheapest month to fly from PSA to STL. Traveling outside of peak seasons is often the key to better flight prices.
What is the cheapest airline that flies from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from PSA to STL. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL)?
You'll need to take a flight with a layover if you're traveling from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from PSA to STL?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL)?
To land at Lambert-St. Louis Intl. Airport (STL) without delays, pick a flight that takes off from Galileo Galilei Airport (PSA) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your plane ticket from PSA to STL just before your getaway is usually more expensive. However, if there's some wiggle room with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book a PSA to STL flight and hotel package?
Securing a PSA to STL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our impressive range of accommodations and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to Lambert-St. Louis Intl. Airport (STL)?
In most instances, you can modify or cancel your PSA to STL flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you want further information, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Galileo Galilei
Destination airport
Lambert-St. Louis Intl.
Roundtrip price
$764
Distance
4899 mi

Book with confidence

Book with confidence

Pisa to St. Louis Flights

The cheapest times to fly from Pisa to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to St. Louis are during the month of February. You can find some of the cheapest flights from Pisa to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to St. Louis

Sunday is one of the best days to book for cheap flights from Pisa to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $498 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pisa to St. Louis Flights

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*Available to One Key members.