$283 Cheap flights from Panama City to Myrtle Beach (PTY to MYR)

Myrtle Beach showing general coastal views, swimming and a city

Popular airlines from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR)

American Airlines
American Airlines
Delta
Delta
United
United

Cheap Flights from Panama City to Myrtle Beach (PTY-MYR)

Prices were available within the past 7 days and start at $283 for one-way flights and $470 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

Thu, Jan 29 - Sun, Feb 1

PTY

Panama City

MYR

Myrtle Beach

$470

Roundtrip

found 1 day ago

Wed, Jan 28 - Mon, Feb 2

PTY

Panama City

MYR

Myrtle Beach

$471

Roundtrip

found 1 day ago

Mon, Jan 26 - Fri, Jan 30

PTY

Panama City

MYR

Myrtle Beach

$482

Roundtrip

found 4 hours ago

Thu, Jan 29 - Sat, Jan 31

PTY

Panama City

MYR

Myrtle Beach

$492

Roundtrip

found 1 day ago

Wed, Jan 28 - Sat, Jan 31

PTY

Panama City

MYR

Myrtle Beach

$493

Roundtrip

found 1 day ago

Mon, Jan 26 - Fri, Jan 30

PTY

Panama City

MYR

Myrtle Beach

$503

Roundtrip

found 4 hours ago

Mon, Jan 26 - Fri, Jan 30

PTY

Panama City

MYR

Myrtle Beach

$546

Roundtrip

found 4 hours ago

Tue, Jan 27 - Thu, Jan 29

PTY

Panama City

MYR

Myrtle Beach

$569

Roundtrip

found 1 day ago

Mon, Jan 26 - Fri, Jan 30

PTY

Panama City

MYR

Myrtle Beach

$598

Roundtrip

found 4 hours ago

Mon, Jan 26 - Fri, Jan 30

PTY

Panama City

MYR

Myrtle Beach

$600

Roundtrip

found 4 hours ago

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR) cost?

Grab a cheap one-way flight from $283 or cheap return flight from $470 from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.

What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR)?

Flying in January is a good way to save, as it's the cheapest month for flights between PTY and MYR. You'll often find the lowest prices during the off-season.

What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR)?

Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from PTY to MYR. Then, sort your results by "Price (lowest to highest)" to score a great deal.

How many flights per day from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR)?

Direct flights from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and select either "1 Stop" or "2+ Stops."

What day of the week has the most flights from PTY to MYR?

Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.

What is the best time to fly from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR)?

Select a flight from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR) last-minute?

Last-minute bookings from PTY to MYR are usually more expensive. For the cheapest rates, start searching for flights ahead of time. That said, if you can play around with your travel dates, it's possible to find a cheap ticket right before your trip.

Is it cheaper to book a PTY to MYR flight and hotel package?

Compared with arranging hotels and flights separately, booking a PTY to MYR flight and hotel package with Expedia could lead to significant savings. Better still, having it all in one place takes the hassle out of travel planning. Simply pick your flights and choose from our wide range of hotels, then tailor your trip with other add-ons like activities and car rentals.

Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Myrtle Beach Intl. Airport (MYR)?

If you booked your PTY to MYR flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

Travel information

Origin airport	Tocumen Intl.
Destination airport	Myrtle Beach Intl.
Airlines serving	American Airlines, Delta, United
Roundtrip price	$469
Distance	1700 mi

Book with confidence

Panama City to Myrtle Beach Flights

The cheapest times to fly from Panama City to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Myrtle Beach are during the month of January. You can find some of the cheapest flights from Panama City to Myrtle Beach with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Panama City to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Panama City to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Panama City to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $283 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.