$69 Cheap Flights from Fort Myers (RSW) to St. Louis (STL)

View $69 flight on Thu, Oct 23, 2025Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Fort Myers to St. Louis (RSW-STL)

Prices were available within the past 7 days and start at $69 for one-way flights and $137 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Thu, Oct 30 - Sun, Nov 2
RSW
Fort Myers
STL
St. Louis
$137 Roundtrip, found 1 hour ago
$137
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Thu, Oct 30 from Fort Myers to St. Louis, returning Sun, Nov 2, priced at $137 found 1 hour ago
Southwest Airlines
Thu, Oct 30 - Sun, Nov 2
RSW
Fort Myers
STL
St. Louis
$147 Roundtrip, found 1 hour ago
$147
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Thu, Oct 30 from Fort Myers to St. Louis, returning Sun, Nov 2, priced at $147 found 1 hour ago
Southwest Airlines
Sun, Aug 31 - Thu, Sep 4
RSW
Fort Myers
STL
St. Louis
$157 Roundtrip, found 11 hours ago
$157
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Sun, Aug 31 from Fort Myers to St. Louis, returning Thu, Sep 4, priced at $157 found 11 hours ago
American Airlines
Thu, Oct 30 - Sun, Nov 2
RSW
Fort Myers
STL
St. Louis
$162 Roundtrip, found 1 hour ago
$162
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Oct 30 from Fort Myers to St. Louis, returning Sun, Nov 2, priced at $162 found 1 hour ago
Delta
Thu, Oct 30 - Sun, Nov 2
RSW
Fort Myers
STL
St. Louis
$167 Roundtrip, found 1 hour ago
$167
Roundtrip
found 1 hour ago
Select Delta flight, departing Thu, Oct 30 from Fort Myers to St. Louis, returning Sun, Nov 2, priced at $167 found 1 hour ago
Southwest Airlines
Sun, Aug 31 - Thu, Sep 4
RSW
Fort Myers
STL
St. Louis
$172 Roundtrip, found 11 hours ago
$172
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Sun, Aug 31 from Fort Myers to St. Louis, returning Thu, Sep 4, priced at $172 found 11 hours ago
Southwest Airlines
Tue, Oct 14 - Tue, Oct 21
RSW
Fort Myers
STL
St. Louis
$177 Roundtrip, found 1 hour ago
$177
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Tue, Oct 14 from Fort Myers to St. Louis, returning Tue, Oct 21, priced at $177 found 1 hour ago
United
Tue, Oct 14 - Tue, Oct 21
RSW
Fort Myers
STL
St. Louis
$182 Roundtrip, found 1 hour ago
$182
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Oct 14 from Fort Myers to St. Louis, returning Tue, Oct 21, priced at $182 found 1 hour ago
American Airlines
Wed, Dec 10 - Tue, Dec 30
RSW
Fort Myers
STL
St. Louis
$183 Roundtrip, found 5 days ago
$183
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 10 from Fort Myers to St. Louis, returning Tue, Dec 30, priced at $183 found 5 days ago
Alaska Airlines
Sat, Aug 23 - Sun, Aug 24
RSW
Fort Myers
STL
St. Louis
$17,250 Roundtrip, found 2 hours ago
$17,250
Roundtrip
found 2 hours ago
Select Alaska Airlines flight, departing Sat, Aug 23 from Fort Myers to St. Louis, returning Sun, Aug 24, priced at $17,250 found 2 hours ago

Find the cheapest month to fly from Fort Myers (RSW) to St. Louis (STL)

October is typically the cheapest month to fly

From $147 - $564 per traveler.

Graph displaying average flight prices per month

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $209
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $209
Flights from Fort Myers (RSW) to St. Louis (STL)
Origin airport
Southwest Florida Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$137
Distance
980 mi
Average flight time
1 hour 34 mins

Fort Myers to St. Louis Flights

The cheapest times to fly from Fort Myers to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to St. Louis are during the month of October. You can find some of the cheapest flights from Fort Myers to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to St. Louis

Sunday is one of the best days to book for cheap flights from Fort Myers to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $69 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL) cost?
Snag cheap return tickets starting at $137 from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Southwest Airlines flight leaving RSW on August 16 2025 and touching down at STL. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from RSW to STL?
The cheapest flights from RSW to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
Board a nonstop flight with Southwest Airlines and head straight from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL).
What is the cheapest airline that flies from RSW to STL?
With tickets starting at $69 for a one-way flight from RSW to STL, Southwest Airlines is currently the cheapest carrier on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from RSW on August 26 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
With, on average, 3 nonstop flights that operate from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL) each day, you'll be jetting off in no time.
What are the most popular departure times for flights from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
The 8 AM departures from RSW to STL are the most sought after. These flights can come with a higher price due to their popularity. If you want to save on your fare, book during off-peak hours.
What day of the week has the most flights from RSW to STL?
Depart on a Friday if you're looking for the largest selection of flights from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL).
What is the earliest flight from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
Catch the earliest flight at around 6:45AM UTC-5, heading out of Southwest Florida Intl. Airport (RSW). You'll be traveling for roughly 2h 45m, coming in to land at Lambert-St. Louis Intl. Airport (STL) at approximately 8:30AM UTC-6.
How long does it take to fly from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
The average flight time from RSW to STL is 2 hours and 46 minutes, covering a distance of 980 mi.
What airline has the least delays from RSW to STL?
Southwest Airlines has the best performance for on-time direct flights from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL), with an on-time rating of 82%. Use the Expedia App to check your flight schedule before you leave and get real-time alerts about any changes.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
To land at Lambert-St. Louis Intl. Airport (STL) on schedule, book a flight that leaves from Southwest Florida Intl. Airport (RSW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from Southwest Florida Intl. Airport (RSW)?
If you're taking a direct flight from Southwest Florida Intl. Airport (RSW) to St. Louis, Lambert-St. Louis Intl. Airport (STL) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Last-minute fares from RSW to STL are usually more expensive. To lock in the lowest prices, start searching for flights as early as possible. That said, if you're flexible with your travel dates, you may score a cheap fare right before your trip.
Is it cheaper to book a RSW to STL flight and hotel package?
Booking a RSW to STL flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our wide range of stays and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it's possible to reschedule or cancel your RSW to STL flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

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