$65 Cheap Flights from San Diego (SAN) to St. Louis (STL)

View $65 flight on Thu, Nov 13, 2025Opens in a new window

Popular airlines from San Diego Intl. Airport (SAN) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from San Diego to St. Louis (SAN-STL)

Prices were available within the past 7 days and start at $65 for one-way flights and $130 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Nov 13 - Mon, Nov 17
SAN
San Diego
STL
St. Louis
$130 Roundtrip, just found
$130
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Nov 13 from San Diego to St. Louis, returning Mon, Nov 17, priced at $130 just found
Frontier Airlines
Thu, Nov 13 - Mon, Nov 17
SAN
San Diego
STL
St. Louis
$168 Roundtrip, just found
$168
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Nov 13 from San Diego to St. Louis, returning Mon, Nov 17, priced at $168 just found
Frontier Airlines
Thu, Nov 13 - Mon, Nov 17
SAN
San Diego
STL
St. Louis
$176 Roundtrip, just found
$176
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Nov 13 from San Diego to St. Louis, returning Mon, Nov 17, priced at $176 just found
Frontier Airlines
Thu, Dec 4 - Fri, Dec 5
SAN
San Diego
STL
St. Louis
$182 Roundtrip, found 1 day ago
$182
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 4 from San Diego to St. Louis, returning Fri, Dec 5, priced at $182 found 1 day ago
American Airlines
Tue, Dec 9 - Mon, Dec 15
SAN
San Diego
STL
St. Louis
$192 Roundtrip, found 6 days ago
$192
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Dec 9 from San Diego to St. Louis, returning Mon, Dec 15, priced at $192 found 6 days ago
Frontier Airlines
Thu, Dec 11 - Fri, Dec 12
SAN
San Diego
STL
St. Louis
$192 Roundtrip, found 1 day ago
$192
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 11 from San Diego to St. Louis, returning Fri, Dec 12, priced at $192 found 1 day ago
Frontier Airlines
Sat, Nov 8 - Thu, Nov 13
SAN
San Diego
STL
St. Louis
$196 Roundtrip, found 1 hour ago
$196
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sat, Nov 8 from San Diego to St. Louis, returning Thu, Nov 13, priced at $196 found 1 hour ago
United
Tue, Dec 9 - Mon, Dec 15
SAN
San Diego
STL
St. Louis
$205 Roundtrip, found 6 days ago
$205
Roundtrip
found 6 days ago
Select United flight, departing Tue, Dec 9 from San Diego to St. Louis, returning Mon, Dec 15, priced at $205 found 6 days ago
Delta
Mon, Dec 15 - Tue, Dec 16
SAN
San Diego
STL
St. Louis
$228 Roundtrip, found 5 days ago
$228
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Dec 15 from San Diego to St. Louis, returning Tue, Dec 16, priced at $228 found 5 days ago
Southwest Airlines
Thu, Dec 11 - Mon, Dec 15
SAN
San Diego
STL
St. Louis
$294 Roundtrip, found 5 hours ago
$294
Roundtrip
found 5 hours ago
Select Southwest Airlines flight, departing Thu, Dec 11 from San Diego to St. Louis, returning Mon, Dec 15, priced at $294 found 5 hours ago

Find the cheapest month to fly from San Diego (SAN) to St. Louis (STL)

November is typically the cheapest month to fly

From $118 - $449 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $507
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $507

Frequently asked questions

How much does a flight from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL) cost?
Get a cheap one-way flight from $65 or cheap return flight from $130 from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
November is the cheapest month to fly from SAN to STL. Planning your trip for the off-season is often the key to landing a great deal.
Which airlines fly direct from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
Fly directly from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL) on a Southwest Airlines flight.
What is the cheapest airline that flies from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest SAN to STL flight.
How many flights per day from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
On average, San Diego Intl. Airport (SAN) only offers 1 direct flight to Lambert-St. Louis Intl. Airport (STL) each day. To explore more options, try Expedia's easy-to-use filters. Simply enter your details, then choose "1 Stop" or "2+ Stops" to find flights offering layovers.
What are the most popular departure times for flights from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
Flights between SAN and STL tend to be busiest at 9 AM. If you want a quieter experience and potentially cheaper prices, choose a departure outside the usual busy windows.
What day of the week has the most flights from SAN to STL?
Sunday offers the most flights from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL). Consider taking off on this day and you'll have the best chance of finding a departure that fits your itinerary.
What is the earliest flight from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
San Diego Intl. Airport (SAN)'s earliest flight to Lambert-St. Louis Intl. Airport (STL) leaves at approximately 6:50AM UTC-8. With a travel duration of 3h 25m, you'll touch down at around 12:15PM UTC-6.
How long does it take to fly from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
The average flight time from SAN to STL is 3 hours and 26 minutes, covering a total distance of 1,550 mi.
What airline has the least delays from SAN to STL?
Alaska Airlines has the strongest track record for on-time direct flights from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL), with an on-time score of 82%. Use the Expedia App to look up your flight schedule before you leave and get notified of any changes.
What is the best time to fly from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
To touch down at Lambert-St. Louis Intl. Airport (STL) without delays, book a flight that leaves from San Diego Intl. Airport (SAN) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from San Diego Intl. Airport (SAN)?
If you've booked a direct flight from San Diego Intl. Airport (SAN) to St. Louis, Lambert-St. Louis Intl. Airport (STL) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Last-minute bookings from SAN to STL are typically more expensive. To lock in the lowest rates, start looking for flights ahead of time. That being said, if your travel plans are flexible, you may find a cheap ticket just before your departure.
Is it cheaper to book a SAN to STL flight and hotel package?
Compared with arranging flights and hotels separately, booking a SAN to STL flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of hotels, then tailor your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from San Diego Intl. Airport (SAN) to Lambert-St. Louis Intl. Airport (STL)?
In most cases, you can modify or cancel your SAN to STL flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you'd like more details, head to our Customer Service portal.

Travel information

Origin airport
San Diego Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$130
Distance
1554 mi
Average flight time
6 hours 23 mins

Book with confidence

San Diego to St. Louis Flights

The cheapest times to fly from San Diego to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Diego to St. Louis are during the month of November. You can find some of the cheapest flights from San Diego to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Diego to St. Louis

Sunday is one of the best days to book for cheap flights from San Diego to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Diego to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Diego to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $65 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Diego to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Diego to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Diego to St. Louis Flights

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*Available to One Key members.