$556 Cheap Flights from Santiago (SCL) to Myrtle Beach (MYR)

View $556 flight on Thu, Jan 22, 2026Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from Santiago to Myrtle Beach (SCL-MYR)

Prices were available within the past 7 days and start at $556 for one-way flights and $813 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$813 Roundtrip, found 3 days ago
$813
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $813 found 3 days ago
American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$815 Roundtrip, found 3 days ago
$815
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $815 found 3 days ago
American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$829 Roundtrip, found 3 days ago
$829
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $829 found 3 days ago
American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$832 Roundtrip, found 3 days ago
$832
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $832 found 3 days ago
American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$863 Roundtrip, found 3 days ago
$863
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $863 found 3 days ago
American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$865 Roundtrip, found 3 days ago
$865
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $865 found 3 days ago
American Airlines
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$868 Roundtrip, found 3 days ago
$868
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $868 found 3 days ago
American Airlines
Thu, Sep 25 - Thu, Oct 2
SCL
Santiago
MYR
Myrtle Beach
$878 Roundtrip, found 3 days ago
$878
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Sep 25 from Santiago to Myrtle Beach, returning Thu, Oct 2, priced at $878 found 3 days ago
Delta
Sat, Sep 27 - Sat, Oct 4
SCL
Santiago
MYR
Myrtle Beach
$2,434 Roundtrip, found 3 days ago
$2,434
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 27 from Santiago to Myrtle Beach, returning Sat, Oct 4, priced at $2,434 found 3 days ago
LATAM Airlines Group
Sun, Sep 28 - Mon, Sep 29
SCL
Santiago
MYR
Myrtle Beach
$2,843 Roundtrip, found 2 days ago
$2,843
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, Sep 28 from Santiago to Myrtle Beach, returning Mon, Sep 29, priced at $2,843 found 2 days ago

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR) cost?
Grab a cheap one-way flight from $556 or cheap return flight from $813 from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR)?
The cheapest month to fly from SCL to MYR is September, when there's less demand. Off-peak season is generally when better flight deals are available between these airports.
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR)?
To find the cheapest airline that'll fly you from SCL to MYR, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR)?
You'll need to catch a flight with a layover when traveling from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from SCL to MYR?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR)?
To reach Myrtle Beach Intl. Airport (MYR) without delays, choose a flight that takes off from Arturo Merino Benitez Airport (SCL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR) last-minute?
Waiting until just before your trip to book your flight from SCL to MYR generally means paying more. While you might find some last-minute offers, they aren't always guaranteed. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a SCL to MYR flight and hotel package?
Compared with arranging hotels and flights separately, booking a SCL to MYR flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place takes the hassle out of travel planning. Just pick your flights and choose from our wide range of stays, then personalize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Myrtle Beach Intl. Airport (MYR)?
In most instances, you can cancel or reschedule your SCL to MYR flight. However, there may be additional charges, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want further details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
Myrtle Beach Intl.
Roundtrip price
$812
Distance
4664 mi

Book with confidence

Book with confidence

Santiago to Myrtle Beach Flights

The cheapest times to fly from Santiago to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Myrtle Beach are during the month of September. You can find some of the cheapest flights from Santiago to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Santiago to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $556 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santiago to Myrtle Beach Flights

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*Available to One Key members.