$71 Cheap Flights from Orange County (SNA) to St. Louis (STL)

View $71 flight on Thu, Jan 22, 2026Opens in a new window

Popular airlines from John Wayne Airport (SNA) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Orange County to St. Louis (SNA-STL)

Prices were available within the past 7 days and start at $71 for one-way flights and $140 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Tue, Nov 18 - Mon, Dec 8
SNA
Orange County
STL
St. Louis
$140 Roundtrip, found 4 days ago
$140
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Nov 18 from Orange County to St. Louis, returning Mon, Dec 8, priced at $140 found 4 days ago
Frontier Airlines
Tue, Nov 18 - Fri, Dec 5
SNA
Orange County
STL
St. Louis
$144 Roundtrip, found 4 days ago
$144
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Nov 18 from Orange County to St. Louis, returning Fri, Dec 5, priced at $144 found 4 days ago
Frontier Airlines
Tue, Nov 18 - Wed, Dec 10
SNA
Orange County
STL
St. Louis
$147 Roundtrip, found 4 days ago
$147
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Nov 18 from Orange County to St. Louis, returning Wed, Dec 10, priced at $147 found 4 days ago
Frontier Airlines
Thu, Nov 13 - Wed, Nov 19
SNA
Orange County
STL
St. Louis
$160 Roundtrip, found 5 days ago
$160
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Orange County to St. Louis, returning Wed, Nov 19, priced at $160 found 5 days ago
Frontier Airlines
Thu, Nov 13 - Mon, Nov 17
SNA
Orange County
STL
St. Louis
$176 Roundtrip, found 3 days ago
$176
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Orange County to St. Louis, returning Mon, Nov 17, priced at $176 found 3 days ago
Frontier Airlines
Thu, Nov 13 - Mon, Nov 17
SNA
Orange County
STL
St. Louis
$186 Roundtrip, found 17 hours ago
$186
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Orange County to St. Louis, returning Mon, Nov 17, priced at $186 found 17 hours ago
Delta
Thu, Mar 5 - Mon, Mar 9
SNA
Orange County
STL
St. Louis
$276 Roundtrip, found 7 hours ago
$276
Roundtrip
found 7 hours ago
Select Delta flight, departing Thu, Mar 5 from Orange County to St. Louis, returning Mon, Mar 9, priced at $276 found 7 hours ago
Hawaiian Airlines
Mon, Dec 15 - Tue, Jan 6
SNA
Orange County
STL
St. Louis
$314 Roundtrip, found 1 hour ago
$314
Roundtrip
found 1 hour ago
Select Hawaiian Airlines flight, departing Mon, Dec 15 from Orange County to St. Louis, returning Tue, Jan 6, priced at $314 found 1 hour ago
American Airlines
Mon, Nov 24 - Thu, Nov 27
SNA
Orange County
STL
St. Louis
$332 Roundtrip, found 13 hours ago
$332
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Nov 24 from Orange County to St. Louis, returning Thu, Nov 27, priced at $332 found 13 hours ago
United
Wed, Dec 24 - Wed, Dec 31
SNA
Orange County
STL
St. Louis
$333 Roundtrip, found 8 hours ago
$333
Roundtrip
found 8 hours ago
Select United flight, departing Wed, Dec 24 from Orange County to St. Louis, returning Wed, Dec 31, priced at $333 found 8 hours ago

Find the cheapest month to fly from Santa Ana (SNA) to St. Louis (STL)

September is typically the cheapest month to fly

From $180 - $698 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $435
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $435

Frequently asked questions

How much does a flight from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $71 or cheap return flight from $140 from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL)?
November is the most affordable month to fly from SNA to STL. Planning your trip for the off-season is often the key to landing a great deal.
Which airlines fly direct from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL)?
You can't take a direct flight from Orange County, CA (SNA-John Wayne) to Lambert-St. Louis Intl. Airport (STL). However, you can easily travel to St. Louis without any layovers by leaving from Los Angeles Intl. Airport (LAX).
What is the cheapest airline that flies from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from SNA to STL. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL)?
There are no daily nonstop flights available from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from SNA to STL?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL)?
To reach Lambert-St. Louis Intl. Airport (STL) on schedule, book a flight that leaves from John Wayne Airport (SNA) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Waiting until just before your trip to book your flight from SNA to STL generally means paying more. While you may come across some last-minute offers, they're not always guaranteed. Keep your travel plans flexible for the best chance of scoring a bargain.
Is it cheaper to book a SNA to STL flight and hotel package?
Compared with arranging flights and hotels separately, booking a SNA to STL flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place takes the hassle out of travel planning. Simply secure your flights and choose from our extensive range of hotels, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from John Wayne Airport (SNA) to Lambert-St. Louis Intl. Airport (STL)?
If you reserved your SNA to STL flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you want more information.

Travel information

Origin airport
John Wayne
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, Southwest Airlines, United
Roundtrip price
$140
Distance
1565 mi
Average flight time
8 hours 16 mins

Book with confidence

Orange County to St. Louis Flights

The cheapest times to fly from Orange County to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Orange County to St. Louis are during the month of November. You can find some of the cheapest flights from Orange County to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Orange County to St. Louis

Sunday is one of the best days to book for cheap flights from Orange County to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Orange County to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Orange County to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $71 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Orange County to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Orange County to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Orange County to St. Louis Flights

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*Available to One Key members.