$335 Cheap Flights from St. Louis (STL) to Quito (UIO)

View $335 flight on Wed, Oct 1, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO)

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Cheap Flights from St. Louis to Quito (STL-UIO)

Prices were available within the past 7 days and start at $335 for one-way flights and $545 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Jan 20 - Tue, Feb 3
STL
St. Louis
UIO
Quito
$545 Roundtrip, found 15 hours ago
$545
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Jan 20 from St. Louis to Quito, returning Tue, Feb 3, priced at $545 found 15 hours ago
Delta
Tue, Mar 10 - Tue, Mar 17
STL
St. Louis
UIO
Quito
$614 Roundtrip, found 13 hours ago
$614
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Mar 10 from St. Louis to Quito, returning Tue, Mar 17, priced at $614 found 13 hours ago
United
Thu, Dec 11 - Tue, Dec 23
STL
St. Louis
UIO
Quito
$614 Roundtrip, found 15 hours ago
$614
Roundtrip
found 15 hours ago
Select United flight, departing Thu, Dec 11 from St. Louis to Quito, returning Tue, Dec 23, priced at $614 found 15 hours ago
Delta
Sun, Mar 8 - Tue, Mar 17
STL
St. Louis
UIO
Quito
$619 Roundtrip, found 13 hours ago
$619
Roundtrip
found 13 hours ago
Select Delta flight, departing Sun, Mar 8 from St. Louis to Quito, returning Tue, Mar 17, priced at $619 found 13 hours ago
Delta
Sun, Mar 15 - Tue, Mar 24
STL
St. Louis
UIO
Quito
$622 Roundtrip, found 13 hours ago
$622
Roundtrip
found 13 hours ago
Select Delta flight, departing Sun, Mar 15 from St. Louis to Quito, returning Tue, Mar 24, priced at $622 found 13 hours ago
United
Mon, Mar 2 - Mon, Mar 9
STL
St. Louis
UIO
Quito
$623 Roundtrip, found 5 days ago
$623
Roundtrip
found 5 days ago
Select United flight, departing Mon, Mar 2 from St. Louis to Quito, returning Mon, Mar 9, priced at $623 found 5 days ago
Delta
Fri, Apr 24 - Mon, May 11
STL
St. Louis
UIO
Quito
$624 Roundtrip, found 13 hours ago
$624
Roundtrip
found 13 hours ago
Select Delta flight, departing Fri, Apr 24 from St. Louis to Quito, returning Mon, May 11, priced at $624 found 13 hours ago
American Airlines
Fri, Apr 24 - Mon, May 11
STL
St. Louis
UIO
Quito
$629 Roundtrip, found 13 hours ago
$629
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, Apr 24 from St. Louis to Quito, returning Mon, May 11, priced at $629 found 13 hours ago
LATAM Airlines Group
Thu, Oct 16 - Thu, Oct 23
STL
St. Louis
UIO
Quito
$634 Roundtrip, found 18 hours ago
$634
Roundtrip
found 18 hours ago
Select LATAM Airlines Group flight, departing Thu, Oct 16 from St. Louis to Quito, returning Thu, Oct 23, priced at $634 found 18 hours ago
avianca
Tue, Sep 30 - Sat, Oct 11
STL
St. Louis
UIO
Quito
$811 Roundtrip, found 3 days ago
$811
Roundtrip
found 3 days ago
Select avianca flight, departing Tue, Sep 30 from St. Louis to Quito, returning Sat, Oct 11, priced at $811 found 3 days ago

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO) cost?
Secure a cheap one-way flight from $335 or cheap return flight from $545 from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO)?
Traveling in January can help you save, as it's the cheapest month for flights between STL and UIO. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from STL to UIO. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO)?
There are no daily nonstop flights departing from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from STL to UIO?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO)?
To avoid possible delays on the Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO) last-minute?
Booking your ticket from STL to UIO shortly before your trip is generally more expensive. However, if there's some wiggle room with your departure times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a STL to UIO flight and hotel package?
Booking a STL to UIO flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our extensive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Mariscal Sucre Intl. Airport (UIO)?
In most instances, you can modify or cancel your STL to UIO flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you want more information, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Mariscal Sucre Intl.
Airlines serving
Air Canada, American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$544
Distance
2791 mi

Book with confidence

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St. Louis to Quito Flights

The cheapest times to fly from St. Louis to Quito

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Quito are during the month of January. You can find some of the cheapest flights from St. Louis to Quito with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Quito

Sunday is one of the best days to book for cheap flights from St. Louis to Quito: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Quito

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Quito in 2025. You can also book with separate airlines for your outbound and return journeys, from $335 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Quito flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Quito airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Quito Flights

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*Available to One Key members.