Title: The Best 4 Star Hotels in Alachua, FL from $109 | Expedia.com [Alachua Travel Guide](https://expedia.com/Alachua.dx5933)[Hotels in Alachua](https://expedia.com/Alachua-Hotels.d5933.Travel-Guide-Hotels)[Vacation Rentals in Alachua](https://expedia.com/Alachua-Vacation-Rentals.d5933.Travel-Guide-VacationRentals)[Flights to Alachua](https://expedia.com/Cheap-Flights-To-Alachua.d5933.Travel-Guide-Flights)[Car Rentals in Alachua](https://expedia.com/Car-Rentals-In-Alachua.d5933.Car-Rental-Guide)[Alachua Vacation Packages](https://expedia.com/Alachua.d5933.Destination-Travel-Guides) ![Hay Bales and Farmland in Alachua County, Florida](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Alachua 4 Star Hotels Tonight [Mar 19 - Mar 20](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-03-19&endDate=2026-03-20&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 20 - Mar 21](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-03-20&endDate=2026-03-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Alachua 4-star hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/13133f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/d4e32e3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/66d2b782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Gainesville [](https://www.expedia.com/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) Gainesville 7.8/10 Good (1,003 reviews) "Hotel had a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lydia $97 nightly $109 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/a9873a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/fde9d20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/f653a0dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/w2460h1531x0y0-75bb46b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Landing Apartments Newberry [](https://www.expedia.com/Newberry-Hotels-Barsala-At-The-Vanguard-Apartments.h111068878.Hotel-Information) Newberry 10/10 Exceptional (50 reviews) "Great stay very clean better than any hotel around the area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diogenes [](https://www.expedia.com/Newberry-Hotels-Barsala-At-The-Vanguard-Apartments.h111068878.Hotel-Information) ![Luxury Apartment | In-room dining](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/83b7eb2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/a6158955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | 2 bedrooms, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/9941815d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/56376f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar [](https://www.expedia.com/Gainesville-Hotels-The-Scholar.h112021506.Hotel-Information) Gainesville 8.6/10 Excellent (9 reviews) "Clean, comfortable, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth $256 nightly $288 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Gainesville-Hotels-The-Scholar.h112021506.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/23000000/22500000/22493000/22492934/31a9d8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast for a fee](https://images.trvl-media.com/lodging/23000000/22500000/22493000/22492934/136738ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/23000000/22500000/22493000/22492934/c071a75b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22500000/22493000/22492934/58486aea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Herlong Mansion Bed & Breakfast [](https://www.expedia.com/Gainesville-Hotels-Herlong-Mansion-Bed-Breakfast.h22492934.Hotel-Information) Micanopy 9.4/10 Exceptional (313 reviews) "Kim was so friendly and helpful, the setting is serene, and the breakfast was prompt and delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler [](https://www.expedia.com/Gainesville-Hotels-Herlong-Mansion-Bed-Breakfast.h22492934.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/91000000/90050000/90048500/90048452/4d4ed91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room | 2 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/91000000/90050000/90048500/90048452/f259cfbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90050000/90048500/90048452/fed1ee71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/91000000/90050000/90048500/90048452/43d6a396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful modern and close to everything [](https://www.expedia.com/Gainesville-Hotels-Peaceful-Modern-And-Close-To-Everything.h90048452.Hotel-Information) Gainesville 9.6/10 Exceptional (4 reviews) "Fantastic property and rental for a weekend in Gainesville. Very clean, well stocked and the owner clearly takes pride in her property. Excellent finishes, very comfortable beds and she communicated quickly and effectively when reached out to. Would recommend and will use again when in Gainesville. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) todd [](https://www.expedia.com/Gainesville-Hotels-Peaceful-Modern-And-Close-To-Everything.h90048452.Hotel-Information) ![50-inch plasma TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/91000000/90050000/90049500/90049490/1e110aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch plasma TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/91000000/90050000/90049500/90049490/bfd2e731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90050000/90049500/90049490/e5f21a9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/91000000/90050000/90049500/90049490/bef471a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Convenient and Modern Haven [](https://www.expedia.com/Gainesville-Hotels-Quiet-Convenient-And-Modern-Haven.h90049490.Hotel-Information) Gainesville 10/10 Exceptional (5 reviews) "Well appointed and very clean. This was soooo much better than a hotel for our short stay. Will definitely use again when we come to town. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Justin [](https://www.expedia.com/Gainesville-Hotels-Quiet-Convenient-And-Modern-Haven.h90049490.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/122000000/121420000/121417100/121417042/1ef0b88e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/122000000/121420000/121417100/121417042/44a0831b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/122000000/121420000/121417100/121417042/17114c05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/122000000/121420000/121417100/121417042/d01a8862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 Mi to UF Campus: Modern Condo w/ Pool Access! [](https://www.expedia.com/Gainesville-Hotels-2-Mi-To-UF-Campus-Modern-Condo-W-Pool-Access.h121417042.Hotel-Information) Gainesville [](https://www.expedia.com/Gainesville-Hotels-2-Mi-To-UF-Campus-Modern-Condo-W-Pool-Access.h121417042.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Alachua-Hotels.s40-0-d5933.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Alachua-Hotels.s40-0-d5933.Travel-Guide-Filter-Hotels) ## Learn more about Alachua Lace up your hiking boots and explore the natural wonders of Mill Creek Preserve's winding trails. After your outdoor adventure, unwind at the City of Alachua Recreation Center or browse local treasures at the Alachua Library Branch. [See all hotels in Alachua](https://www.expedia.com/Hotel-Search?startDate=2026-04-02&endDate=2026-04-03&adults=2®ionId=5933) ![Hay Bales and Farmland in Alachua County, Florida](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=900&h=370&p=1&q=high) ## Top Alachua Hotel Reviews ![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/13133f5c_y.jpg) ### DoubleTree by Hilton Gainesville 6/10 Okay "Meds are good. Lodging was good. Wouldn't recommend eating in the restaurant" [](https://expedia.com/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ## Find out more about Alachua ## Alachua Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Alachua, Florida are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Alachua 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Alachua. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Alachua, Florida, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Alachua hotels offer everything your heart desires. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Alachua? > - Search for the lowest price from $109 ### What's the difference between 5-star and 4-star hotels in Alachua? ### Does Alachua have any 4-star all-inclusive resorts? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near San Felasco Hammock Preserve State Park ](https://www.expedia.com/San-Felasco-Hammock-Preserve-State-Park-Hotels.0-l6128058-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in High Springs ](https://www.expedia.com/5Star-High-Springs-Hotels.s50-0-d183096.Travel-Guide-Filter-Hotels) - [4 Star Hotels in High Springs ](https://www.expedia.com/4Star-High-Springs-Hotels.s40-0-d183096.Travel-Guide-Filter-Hotels) - [3 Star Hotels in High Springs ](https://www.expedia.com/3Star-High-Springs-Hotels.s30-0-d183096.Travel-Guide-Filter-Hotels) - 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