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Find 5 Star Hotels in Port Isabel, TX from $135

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Check availability on Port Isabel 5 Star Hotels

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Sep 5 - Sep 6
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Sep 11 - Sep 13
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Sep 18 - Sep 20

Our top choices for Port Isabel 5-star hotels

A modern two-story house with a swimming pool, wooden deck, and a well-lit interior.
A modern living room with a large sofa, a coffee table, and a TV on a white cabinet. There are two chairs and a large window with a view of the ocean.
A balcony with a view of the sea, a ceiling fan, and a seating area.
A spacious dining area with a large table set for six, a kitchen in the background, and a view of the ocean through large windows.

1. Spacious Bay

Spacious Bay
Port Isabel
Spacious Bay
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Port Isabel.
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

310 Padre Blvd South Padre Island TX
$135 total
per night
Sep 23 - Sep 24
Margaritaville Beach Resort South Padre Island
Casa Picasso 3 BR Home with Private Pool

Casa Picasso 3 BR Home with Private Pool

118 E Constellation South Padre Island TX
Get rates
7.6/10 Good! (31 reviews)
Casa Picasso 3 BR Home with Private Pool
Sleeps 6 in a 4plex w Pool, Only a Block to Beach

Sleeps 6 in a 4plex w Pool, Only a Block to Beach

124 E Saturn Ln South Padre Island TX
Get ratesSleeps 6 in a 4plex w Pool, Only a Block to Beach
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Port Isabel

Climb the historic lighthouse for sweeping views of South Padre Island and spot dolphins playing in the turquoise waters. Explore the treasures at Pirates Landing pier, where fishing adventures and fresh seafood restaurants create the perfect coastal getaway.

See all hotels in Port Isabel
A coastal highway with a bridge, palm trees, and a city skyline in the background.

Top Port Isabel Hotel Reviews

Find out more about Port Isabel

Indulge yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Port Isabel so popular in the last year. There's no reason to delay a getaway to Port Isabel any longer. Besides, the accommodations in Port Isabel offer great customer service, averaging 3.6 in our ranking system, so you know you're in good hands. Book one of Expedia's luxurious 5-star hotels in Port Isabel and get ready to be pampered like never before. You deserve an outstanding getaway.

5-Star Hotels in Port Isabel

You can expect superior customer service from your hotel. Exceptional customer care, granite-tiled bathrooms, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Port Isabel offer great customer service, averaging 3.6 in our ranking system, so you know you're in good hands. What creature comforts do you want in your lodging? A mud wrap treatment that will leave you feeling outstanding? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A full-body massage to help your cares fall away? Want to see for yourself? Plenty of visitors recommend this location.

Yearning for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Port Isabel are waiting for you to rest up after a busy day.

Your Getaway Starts Today

The results are in, and Port Isabel 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Decide on one of Expedia's Port Isabel 5-star hotels today and soothe yourself in total tranquility tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Port Isabel?
You can find several pricing options for 5-star hotels in Port Isabel on Expedia. How much you'll pay will depend on your travel dates, length of stay and other factors. Compare available properties for your preferred dates and use our pricing and other filters to lock in the ideal upscale stay.
  • Search for the lowest price per night from $135
What makes a hotel 5 stars in Port Isabel?
Outstanding guest service is at the heart of every 5-star hotel in Port Isabel. From the minute you step through the door, staff ensure your every need is met, whether offering luggage assistance and storage or providing in-room massages. Plus, hotels must offer upscale conveniences to meet the standard for a 5-star rating. These can include luxury baths, spa facilities, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Port Isabel?
Expedia's filters are the easiest way to narrow down what you want. Check the "All inclusive" and "5-star" boxes to see the most luxurious resorts in Port Isabel where your meals, lodging, entertainment and activities are included in the upfront price. At these stays, your vacation is absolute indulgence from the moment you step foot in the lobby.

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