Central Iowa Vacations from $462

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Your Central Iowa Vacation

Embrace new adventures with a Central Iowa vacation package. Culture and festivals will make the highlight reel of your getaway. Kick off your trip to Central Iowa with some time exploring Des Moines visiting popular attractions like Iowa State Fairgrounds and Adventureland. Ames is another top city that draws crowds from near and far. Jack Trice Stadium and Hilton Coliseum are two of the top places to see here. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next Central Iowa vacation.

The Latest Central Iowa vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Aspen Select
Comfort Inn & Suites West - Medical Center
The Towers At Kahler Grand Hotel
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
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Where to stay in Central Iowa

Find the best Central Iowa areas and neighborhoods for the activities you enjoy most. Learn more about Central Iowa

Discover the most popular places to visit in Central Iowa

Central Iowa Hotel Deals

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd, Urbandale, IA
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Aug 26 to Aug 27
$87 total
Aug 26 - Aug 27
Total includes taxes and fees
5.6/10 (565 reviews)
Just manage expectations and it’ll be fine!
"We booked to stay during the state fair with our 3 year old. The hotel is older, for sure. Certainly not a luxury establishment. That said, though, our rooms were clean. The AC worked very well in our room, almost freezing us out the first night until we adjusted it. Our room opened to the waterpark ..."

Reviewed on Aug 17, 2025

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $156 total per night from Aug 24 to Aug 25
$156 total
Aug 24 - Aug 25
Total includes taxes and fees
9.4/10 Exceptional! (1,014 reviews)
"Everything was perfect at this lovely hotel except I didn’t care for the restaurant food. Just not suited for my tastebuds."

Reviewed on Aug 19, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Sep 2 to Sep 3
$76 total
Sep 2 - Sep 3
Total includes taxes and fees
7.6/10 Good! (525 reviews)
"It's convenient! Cheaper prices for some of the hotels!"

Reviewed on Aug 17, 2025

Motel 6 West Des Moines, IA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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