Name: Holiday Inn Downtown - Mercy Area by IHG
Price range: $123 total
Rating: 8

Your Central Iowa Vacation

Embrace new adventures with a Central Iowa vacation package. Culture and festivals will make the highlight reel of your getaway. Kick off your trip to Central Iowa with some time exploring Des Moines visiting popular attractions like Iowa State Fairgrounds and Adventureland. Ames is another top city that draws crowds from near and far. Jack Trice Stadium and Hilton Coliseum are two of the top places to see here. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next Central Iowa vacation.

The Latest Central Iowa vacation packages

Price found within the past 48 hours. Click for updated prices.

Renaissance Des Moines Savery Hotel

Downtown Des Moines

per person

Oct 5 - Oct 8

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Des Moines (DSM)

8.6/10 Excellent! (1,002 reviews)

Rooms aren’t great but it is an old building. Front desk staff (David in particular) was very helpful and accommodating.

Reviewed on May 26, 2025

Aspen Select

per person

Aug 14 - Aug 19

found 7 hours ago

Roundtrip non-stop flight included

Minot (MOT) to Rochester (RST)

8.6/10 Excellent! (1,001 reviews)

Lots of construction around property! Hard to walk much less drive. Can’t blame hotel for that. Place was different, rooms had glass walls that faced hallways. With curtain drawn no problem. Good restaurant right next door. With low price we paid pretty satisfied.

Reviewed on Jul 14, 2025

The Towers At Kahler Grand Hotel

Downtown Rochester

per person

Aug 14 - Aug 19

found 7 hours ago

Roundtrip non-stop flight included

Minot (MOT) to Rochester (RST)

9.4/10 Exceptional! (84 reviews)

Great place to stay if going to Mayo. You don’t have to go outside to get to the buildings at Mayo with the subway level. Food is good for 2 meals a day. There’s room service & deliveries from Instacart if needed for groceries or outside food/beverage source. Personalized concierge service is good. Our stay was 10 days - they accommodated our extended stay flawlessly. My only complaint is the room temperature everywhere; it can be stuffy moving place to place. Take a fan to cool off in your room.

Reviewed on Jun 18, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

per person

Aug 14 - Aug 19

found 7 hours ago

Roundtrip non-stop flight included

Minot (MOT) to Rochester (RST)

8.8/10 Excellent! (781 reviews)

Nice place will stay again

Reviewed on Jul 13, 2025

Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

per person

Aug 14 - Aug 19

found 7 hours ago

Roundtrip non-stop flight included

Minot (MOT) to Rochester (RST)

9.2/10 Wonderful! (940 reviews)

The room was clean and spacious, beds were comfortable and it had a little kitchenette. The parking garage was full, and we had to park on the street where we could see broken bottles and intoxicated people walking around. It wasn’t the safest area to leave a vehicle.

Reviewed on Jul 12, 2025

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Where to stay in Central Iowa

Find the best Central Iowa areas and neighborhoods for the activities you enjoy most. Learn more about Central Iowa

State Historical Society of Iowa Museum which includes landscape views, a skyscraper and a city

Downtown Des Moines

3 out of top 10 points of interest in this area

4.5/5(711 area reviews)

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

Discover the most popular places to visit in Central Iowa

Iowa State University

4.5/5(427 reviews)

Visit this public university to learn about its agricultural history and explore the many museums and cultural centers on the campus.

Adventureland

4/5(201 reviews)

Bring the family to Adventureland and enjoy this exciting amusement park in Altoona. Experience the area's lively festivals and great live music.

Principal Park

4.5/5(62 reviews)

Catch an event at Principal Park during your trip to Des Moines. Experience the area's lively festivals and acclaimed theater scene.

Central Iowa Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

1000 Walnut St, Des Moines, IA

Fully refundableReserve now, pay when you stay

$138 nightly

$154 total

Jul 21 - Jul 22

Total includes taxes and fees

9.4/10 Exceptional! (1,021 reviews)

Great stay!

"Very pretty hotel! Many beautiful details and everyone was very friendly. Very spacious room and ambience was wonderful. *our only complaints, though minor- bed was not the most comfortable (but still fine) and no fan in the bathroom."

Reviewed on Jul 10, 2025

Days Inn & Suites by Wyndham Des Moines Airport

1901 Hackley Ave, Des Moines, IA

Fully refundableReserve now, pay when you stay

$66 nightly

$74 total

Jul 21 - Jul 22

Total includes taxes and fees

8.4/10 Very Good! (1,541 reviews)

"The only thing that we would have liked the air conditioner would have cooled better. I know it was a hot day but didst work very good."

Reviewed on Jul 11, 2025

Holiday Inn Downtown - Mercy Area by IHG

1050 6th Ave, Des Moines, IA

Fully refundable

$110 nightly

$123 total

Jul 21 - Jul 22

Total includes taxes and fees

8/10 Very Good! (1,004 reviews)

"Everything was clean and staff weree very kind!!!"

Reviewed on Jul 12, 2025

See all 1,477 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.