Central Iowa Vacations from $522

Book a Hotel + Flight or Car together to unlock savings

Your Central Iowa Vacation

Embrace new adventures with a Central Iowa vacation package. Culture and festivals will make the highlight reel of your getaway. Kick off your trip to Central Iowa with some time exploring Des Moines visiting popular attractions like Iowa State Fairgrounds and Adventureland. Ames is another top city that draws crowds from near and far. Jack Trice Stadium and Hilton Coliseum are two of the top places to see here. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next Central Iowa vacation.

The Latest Central Iowa vacation packages

Price found within the past 48 hours. Click for updated prices.
Renaissance Des Moines Savery Hotel
Aspen Select
The Towers At Kahler Grand Hotel
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area
Don't see what you're looking for?
See all available trips from Columbus to Central Iowa
View all trips

Where to stay in Central Iowa

Find the best Central Iowa areas and neighborhoods for the activities you enjoy most. Learn more about Central Iowa

Discover the most popular places to visit in Central Iowa

Central Iowa Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $154 total per night from Jul 21 to Jul 22
$154 total
Jul 21 - Jul 22
Total includes taxes and fees
9.4/10 Exceptional! (1,021 reviews)
Great stay!
"Very pretty hotel! Many beautiful details and everyone was very friendly. Very spacious room and ambience was wonderful. *our only complaints, though minor- bed was not the most comfortable (but still fine) and no fan in the bathroom."

Reviewed on Jul 10, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Jul 21 to Jul 22
$74 total
Jul 21 - Jul 22
Total includes taxes and fees
8.4/10 Very Good! (1,541 reviews)
"The only thing that we would have liked the air conditioner would have cooled better. I know it was a hot day but didst work very good."

Reviewed on Jul 11, 2025

Days Inn & Suites by Wyndham Des Moines Airport
Holiday Inn Downtown - Mercy Area by IHG
Holiday Inn Downtown - Mercy Area by IHG
3 out of 5
1050 6th Ave, Des Moines, IA
Fully refundable
$110 nightly
The price is $123 total per night from Jul 21 to Jul 22
$123 total
Jul 21 - Jul 22
Total includes taxes and fees
8/10 Very Good! (1,004 reviews)
"Everything was clean and staff weree very kind!!!"

Reviewed on Jul 12, 2025

Holiday Inn Downtown - Mercy Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Central Iowa Vacation Packages

Central Iowa Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.