Des Moines Vacations from $420

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Your Des Moines Vacation

From its progressive thinking to its friendly locals and rural countryside, there are countless reasons to stay in the riverfront city of Des Moines. Discover these highlights and more when you lock in your vacation package to Des Moines. Eager to start exploring your surroundings? Iowa State Fairgrounds, Iowa State Capitol Building and Blank Park Zoo are just three of the best places to visit during your trip to Des Moines. Your perfect Des Moines vacation is a couple of clicks away. Explore hotels, flights and more on Expedia for an adventure that's tailored to suit your style.

The Latest Des Moines vacation packages

Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Des Moines Airport
Hampton Inn & Suites Des Moines Downtown
Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG
Surety Hotel, Autograph Collection
Holiday Inn Downtown - Mercy Area by IHG
Don't see what you're looking for?
See all available trips from Columbus to Des Moines
View all trips

Where to stay in Des Moines

Find the best Des Moines areas and neighborhoods for the activities you enjoy most. Learn more about Des Moines

Discover the most popular places to visit in Des Moines

Des Moines Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Nov 2 to Nov 3
$155 total
Nov 2 - Nov 3
Total with taxes and fees
9.4/10 Exceptional! (1,004 reviews)
"Very clean and beautiful room. Very comfortable beds!"

Reviewed on Oct 5, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd, Urbandale, IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Oct 12 to Oct 13
$79 total
Oct 12 - Oct 13
Total with taxes and fees
5.6/10 (613 reviews)
"So much fun"

Reviewed on Oct 5, 2025

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Quality Inn & Suites Des Moines - Merle Hay Road

Quality Inn & Suites Des Moines - Merle Hay Road

2.5 out of 5
4995 Merle Hay Rd, Des Moines, IA
Fully refundableReserve now, pay when you stay
$52 nightly
The price is $59 total per night from Oct 30 to Oct 31
$59 total
Oct 30 - Oct 31
Total with taxes and fees
7.4/10 Good! (1,005 reviews)
Quick stop
"Quick over night stop was nice hotel felt safe and clean rooms"

Reviewed on Oct 6, 2025

Quality Inn & Suites Des Moines - Merle Hay Road
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)
Population
210,300
Max Temp Winter
30ºF
Max Temp Summer
80ºF
Top Sights
Adventureland, Blank Park Zoo and Des Moines Art Center

More vacations you might like

Frequently asked questions

How much does a Des Moines vacation package cost?
You'll find cheap prices from $420 on Expedia for your Des Moines getaway. However, a range of factors like the season, choice of hotel and length of stay will determine how much your vacation to Des Moines costs.
What are the cheapest months to go to Des Moines?
November, December and January are the best times to search for cheap Des Moines vacation packages. Traveling in quieter months means you'll typically find lower prices on accommodations and flights.
How many days is enough for Des Moines?
Des Moines vacations can be short or long, but to get a real feel for this destination, we'd say 2 days is about right. This will mean you can fit in major attractions like Des Moines Art Center and Science Center of Iowa and track down some lesser-known gems. Don't miss out on cool areas such as Downtown Des Moines and Greater South Side either. If you plan wisely, you can even schedule a day trip from Des Moines too.
Is it worth booking a vacation package to Des Moines?
It's easy to see why a Des Moines vacation is on the to-do list of many travelers. Major attractions like Greater Des Moines Botanical Garden are just the beginning of things to keep you busy here.
How to find the best Des Moines package deals?
Use Expedia's handy filters to find some fabulous Des Moines package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or search for Des Moines package deals in the off-season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
Is it cheaper to book a Des Moines vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging accommodations and flights separately. Better still, you can personalize your Des Moines escape to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Des Moines?
If you have your Des Moines vacation dates finalized, book as early as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous adventures? Our last-minute deals are great for setting off on a whim.
How to plan a trip to Des Moines?

  1. Choose when to go: Check your schedule and get packing. Your favorite time of year and the activities on offer will also help you decide when to escape to Des Moines.
  2. Plan your budget wisely: In addition to the cost of your accommodations, you should consider other expenses too. These include flights, food and transportation. Also, set aside a little extra for unexpected expenses that may come up during your trip to Des Moines.
  3. Organize your Des Moines escape with our trip planning tool: Look for and book accommodations and things to do all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Des Moines together.
  4. Decide how long to go for: Now that you're up to speed on Des Moines, you can figure out the perfect length of your break. Put together a draft plan and allocate enough time for all the things you want to do.
  5. Combine your flights and hotel: Epic destination, check. Length of stay, check. Now all that's left is to find a Des Moines vacation package that brings all your bookings together.
  6. Book experiences or activities in advance: Whether it's a ticket to a major attraction or a day trip in nature, you won't have to worry about missing out on Des Moines's highlights. Find all the exciting things to do in Des Moines with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later Des Moines vacation packages?
If you're like us, you love going away but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your Des Moines trip over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you see them.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.