Central West End Vacations from $289
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Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
Price was $422, price is now $289 per person
$289
per person
Oct 21 - Oct 24
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8.2/10 Very Good! (760 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.
Reviewed on Jul 26, 2025
The Wildwood Hotel
Save 100% on your flight
Price was $778, price is now $427 per person
$427
per person
Oct 2 - Oct 5
found 20 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.2/10 Wonderful! (1,558 reviews)
The hotel is conveniently located for my visit and was very clean. Unfortunately, we didn’t sleep well for a few reasons.
The first reason was the size of the bed. We were in a handicap accessible standard room with a queen size bed. However, the bed was not a queen. I measured it to be sure and it was a full size. We were crammed.
The second issue was with the blackout curtains. They don’t close all the way.
The third was the noise. I’m not sure what/who was above us but they stomped constantly from 6:30am until ~9 or later.
I took off a star for everything but the noise since that may have been outside of their control.
Reviewed on Aug 19, 2025
The Principal Hotel
Save 100% on your flight
Price was $564, price is now $339 per person
$339
per person
Oct 9 - Oct 14
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9.8/10 Exceptional! (111 reviews)
Overall was the best stay we have had with any one. The only downside would be no hot breakfast unless you went to the restaurant on location. Staff was great and so helpful when we needed anything for the room.
Reviewed on Aug 18, 2025
WorldMark Lake of the Ozarks
Save 100% on your flight
Price was $770, price is now $525 per person
$525
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
9.4/10 Exceptional! (400 reviews)
Great property! Your balcony view is directly on the water. This property offers a dock unused just for guests. I would bring your own raft or float to enjoy the water. The pools and hot tube area are nice, and offer grills for cooking in the pool area and another location.
Check in was great except our room wasn’t ready until 5, the check in time was 4, however they made accommodations to us to offset the delay. It’s close to many fun things to do at the Lake of the Ozarks!! We will be back and will stay here again.
Reviewed on Aug 10, 2025
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
3 out of top 10 points of interest in this area
4/5(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
Aloft St. Louis Cortex
4245 Duncan Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Aug 31 to Sep 1
$133 total
Aug 31 - Sep 1
Total includes taxes and fees
8.6/10 Excellent! (727 reviews)
"Parking was a little challenging but kind staff and shuttle to garage."
Reviewed on Aug 15, 2025
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway, St. Louis, MO
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $262 total per night from Aug 24 to Aug 25
$262 total
Aug 24 - Aug 25
Total includes taxes and fees
8.8/10 Excellent! (1,005 reviews)
"."
Reviewed on Aug 19, 2025
The West End
4215 Lindell Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $124 total per night from Sep 8 to Sep 9
$124 total
Sep 8 - Sep 9
Total includes taxes and fees
8.2/10 Very Good! (282 reviews)
"Great"
Reviewed on Aug 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Cathedral Basilica of St. Louis
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Barnes Jewish Hospital
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Things to do
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
$32
per adult
Best of St. Louis Small Group Tour w/ Arch & River Cruise
$169
per adult
84% of travellers recommend
St. Louis: Guided Small Group City Tour with River Cruise
$174
per adult
100% of travellers recommend
Explore a world of travel with Expedia
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- St. Louis Hotels
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- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
- Car rentals near Cathedral Basilica of St. Louis
- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
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- Car rentals near St. Louis Zoo
- Minivan Car Rentals near St. Louis Zoo
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.