Central West End Vacations from $272
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
HoteLumiere at the Arch - A Caesars Rewards Destination
Downtown St. Louis
Save 100% on your flight
Price was $717, price is now $422 per person
$422
per person
Jan 7 - Jan 11
found 11 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
6.6/10 (1,001 reviews)
It was very nice resort
Reviewed on Nov 20, 2025
Hilton Garden Inn Chesterfield
Price was $458, price is now $322 per person
$322
per person
Jan 7 - Jan 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Just a really nice hotel tucked away from everything, but still close to get whereevre you need to go!
Reviewed on Oct 26, 2025
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
3 out of top 10 points of interest in this area
4/5(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $121 total per night from Dec 13 to Dec 14
$121 total
Dec 13 - Dec 14
Total with taxes and fees
8.2/10 Very Good! (1,006 reviews)
Great room
Reviewed on Nov 30, 2025
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $198 total per night from Dec 14 to Dec 15
$198 total
Dec 14 - Dec 15
Total with taxes and fees
8.8/10 Excellent! (1,006 reviews)
Need to get better quality of wine
Reviewed on Nov 25, 2025
AC Hotel St. Louis Central West End
215 YORK AVENUE St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $150 total per night from Dec 26 to Dec 27
$150 total
Dec 26 - Dec 27
Total with taxes and fees
9/10 Wonderful! (679 reviews)
Extremely clean, comfortable beds and amazing service. Thank you!
Reviewed on Nov 23, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Cathedral Basilica of St. Louis
4.5/5(493 reviews)
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
4/5(9 reviews)
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Barnes Jewish Hospital
4.5/5(227 reviews)
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$32
per adult
St. Louis Premium Driving Tour with Boat Ride & Arch
$148
per adult
100% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
$27
per adult
84% of travellers recommend
Explore a world of travel with Expedia
- St. Louis Hotels
- Hotels near Cathedral Basilica of St. Louis
- Hotels near World Chess Hall of Fame
- Hotels near Barnes Jewish Hospital
- Hotels near St. Louis Children's Hospital
- Hotels near Central West End Station
- Hotels near Forest Park
- Cheap Hotels in St. Louis
- Hotels near Cabanne House
- Hotels near St. Louis Science Center
- Hotels near Pagoda Circle
- Hotels near Contemporary Art Museum St. Louis
- Hotels near The Muny Theater
- Hotels near Fox Theater
- Hotels near Jewel Box
- Hotels near St. Louis University
- Hotels near DeBaliviere Place
- Hotels near St. Louis Zoo
- Hotels near Pulitzer Foundation for the Arts
- Hotels near Sheldon Concert Hall
- Hotels near Dennis and Judith Jones Visitor and Education Center
- Hotels near Grandel Theater
- Hotels near Grand Center
- Luxury Hotels in Grand Center
- Family Hotels in Grand Center
- Boutique Hotels in Grand Center
- La Quinta Inn & Suites Hotels in Grand Center
- Historic Hotels in Grand Center
- Hotels near St. Louis Symphony Orchestra
- Hotels near Powell Symphony Hall
- Hotels near Powell Hall
- Hotels near Downtown St. Louis
- Hotels near Missouri History Museum
- Hotels near Forest Park Station
- Hotels near St. Alphonsus Liguori Catholic Church
- Hotels near Chaifetz Arena
- Hotels near St. Teresa of Avila Catholic Church
- Hotels near The Hill
- Gay friendly Hotels in The Hill
- Hotels near St. Louis Art Museum
- Hotels near Busch Stadium
- Hotels near Missouri Botanical Gardens and Arboretum
- Hotels near Delmar Station
- Hotels near Shaw
- Hotels near Clayton-Tamm
- Hotels near The Gate
- Hotels near Compton Hill Reservoir Park
- Hotels with Free Airport Shuttle in St. Louis
- Hotels near Skinker Station
- Hotels near Compton Heights
- 5 Star Hotels in Compton Heights
- Hotels with Restaurants in Compton Heights
- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
- Car rentals near Cathedral Basilica of St. Louis
- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
- Mini Car Rentals near St. Louis University
- Car rentals near St. Louis Zoo
- Minivan Car Rentals near St. Louis Zoo
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.