Central West End Vacations from $167

Book a Hotel + Flight or Car together to unlock savings

Your Central West End Vacation

Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.

The Latest Central West End Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham

Riverport
$167
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.6/10 Good! (1,012 reviews)
The Wildwood Hotel

The Wildwood Hotel

$380
per person
Nov 12 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,679 reviews)
Nice and cozy room! Host was very helpful on suggesting places to eat.

Reviewed on Oct 9, 2026

The Cheshire

The Cheshire

Save 100% on your flight
$654
per person
Nov 24 - Nov 29
found 22 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8.8/10 Excellent! (1,011 reviews)
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Riverport
$294
per person
Nov 12 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.8/10 Good! (1,005 reviews)
Breakfast was trash. Pool closed frequently. Staff not polite.

Reviewed on Oct 10, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Save 100% on your flight
$635
per person
Nov 12 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,062 reviews)
Wonderful stay for a small bachelorette party. Had a wonderful time!

Reviewed on Oct 10, 2026

Where to stay in Central West End

Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

An ornate hall with arched ceilings and intricate patterns.

Downtown West

2 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Central West End Hotel Deals

The West End

The West End

4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$120 nightly
$136 total
Oct 19 - Oct 20
Total with taxes and fees
The West End
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$186 nightly
$219 total
Nov 1 - Nov 2
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

4630 Lindell St. Louis MO
Fully refundable
$139 nightly
$164 total
Oct 25 - Oct 26
Total with taxes and fees
Hotel Indigo St Louis - Central West End by IHG
See all 1,988 properties in Central West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Central West End attractions

A grand cathedral interior with intricate mosaics, a large central altar, and a circular stained glass window.

Cathedral Basilica of St. Louis

8.6/10 (557 reviews)
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
See properties
A chessboard with pieces outside a building labeled "World Chess Hall of Fame".

World Chess Hall of Fame

8.2/10 (11 reviews)
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
See properties

Blue Strawberry

You can make plans for a show at Blue Strawberry during your trip to St. Louis. Discover the area's top-notch restaurants and its acclaimed theater scene.
See properties

Things to do

The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

$175
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

$15
per traveler
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
See all activities in St. Louis

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.