Central West End Vacations from $325
Book a Hotel + Flight or Car together to unlock savings
Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
$343
per person
Sep 30 - Oct 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,665 reviews)
The location is ideal because it’s in the heart of Wildwood. Quaint and safe. The rate is also great.
I will say that the exterior is beautiful but the interior could really use an upgrade. The furniture and decor is outdated.
The bed was a bit firm for me but it was comfortable enough.
Clean and safe. Dogs allowed. And the movie theater is across the street. It’s walking distance to Walgreen’s and Starbucks and Dierberg’s grocery store.
It’s honestly more affordable than the chains and just as good.
Reviewed on Aug 26, 2026
Remodeled and Inviting Free EV
$541
per person
Nov 2 - Nov 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
10/10 Exceptional! (1 review)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it
Reviewed on Aug 7, 2026
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
3 out of top 10 points of interest in this area
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Downtown West
2 out of top 10 points of interest in this area
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Central West End Hotel Deals
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$220 nightly
$259 total
Sep 20 - Sep 21
Total with taxes and fees
9.2/10 Wonderful! (1,025 reviews)
"Great spot - always love staying"
Reviewed on Aug 25, 2026
Aloft by Marriott St Louis Central West End
4245 Duncan Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
$133 total
Aug 30 - Aug 31
Total with taxes and fees
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$144 nightly
$169 total
Sep 3 - Sep 4
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Central West End attractions
Cathedral Basilica of St. Louis
8.6/10 (557 reviews)
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
8.2/10 (11 reviews)
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Blue Strawberry
You can make plans for a show at Blue Strawberry during your trip to St. Louis. Discover the area's top-notch restaurants and its acclaimed theater scene.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
100% of travellers recommend
StL's Signature "Sights and Bites" - Private Tour in St. Louis
$175
per adult
Lemp Haunted Neighborhood Walking Tour
$25
per adult
84% of travellers recommend
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- Citygarden
- Gateway Arch
- Citygarden Sculpture Park
- St. Louis City Hall
- Fox Theater
- Forest Park
- Magic House - St. Louis Children's Museum
- St. Louis Cathedral
- St. Louis Aquarium at Union Station
- Tower Grove Park
- St. Louis Art Museum
- City Museum
- Cathedral Basilica of St. Louis
- Eugene Field House & St. Louis Toy Museum
- World Chess Hall of Fame
- St. Mary of Victories Catholic Church
- Visit St. Louis
- St. Louis Zoo
- Samuel Cupples House
- St. Louis Science Center
- The MOTO Museum
- Horseshoe St. Louis Casino
- St. Louis Union Station Mini Golf
- Pulitzer Foundation for the Arts
- Jewel Box
- Busch Stadium
- Campbell House Museum
- Old Post Office
- Washington Avenue Historic District
- Gateway Arch National Park
- Cabanne House
- The Muny Theater
- Christ Church Cathedral
- Eads Bridge
- Missouri History Museum
- St. Alphonsus Liguori Catholic Church
- Central Public Library
- Downtown St. Louis Vacations
- Grant's Farm
- Meeting of the Waters Fountain
- Pagoda Circle
- St. Louis Vacations
- Wainwright Building
- Old Courthouse
- Museum at the Gateway Arch
- Bruno David Gallery
- Chaifetz Arena
- Missouri Botanical Gardens and Arboretum
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.