Central West End Vacations from $305
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
HoteLumiere at the Arch - A Caesars Rewards Destination
Downtown St. Louis
Price was $412, price is now $305 per person
$305
per person
Jan 29 - Jan 31
found 11 hours ago
Roundtrip non-stop flight included
Charlotte (CLT) to St. Louis (STL)
13.2/10 Exceptional! (1,001 reviews)
Very nice and convenient location
Reviewed on Oct 29, 2025
Hilton Garden Inn St. Louis/O'Fallon MO
Price was $1,022, price is now $791 per person
$791
per person
Dec 30 - Jan 5
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
17.6/10 Exceptional! (705 reviews)
No vent in the bathroom/shower area
Toilet has weak flush
Other than that a fantastic stay
Reviewed on Oct 20, 2025
Sheraton Westport Plaza Hotel St. Louis
Price was $690, price is now $554 per person
$554
per person
Dec 26 - Dec 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
16.8/10 Exceptional! (853 reviews)
Room clean, staff was great! Have been here multiple times! Will be back soon!
Reviewed on Oct 27, 2025
Hilton Garden Inn Chesterfield
Price was $1,006, price is now $808 per person
$808
per person
Dec 30 - Jan 5
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
16.4/10 Exceptional! (779 reviews)
Just a really nice hotel tucked away from everything, but still close to get whereevre you need to go!
Reviewed on Oct 26, 2025
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
3 out of top 10 points of interest in this area
4/5(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $134 total per night from Dec 20 to Dec 21
$134 total
Dec 20 - Dec 21
Total with taxes and fees
8.2/10 Very Good! (1,003 reviews)
Excellent service, and very convenient.
Reviewed on Nov 12, 2025
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $226 total per night from Nov 23 to Nov 24
$226 total
Nov 23 - Nov 24
Total with taxes and fees
8.8/10 Excellent! (1,001 reviews)
Clean room and staff was great.
Reviewed on Nov 15, 2025
The West End
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $145 total per night from Nov 23 to Nov 24
$145 total
Nov 23 - Nov 24
Total with taxes and fees
8.4/10 Very Good! (387 reviews)
Price is high compare to size of room we got and no breakfast option only coffee. I think in this price can get better option.
Reviewed on Nov 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Cathedral Basilica of St. Louis
4.5/5(493 reviews)
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
4/5(9 reviews)
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Barnes Jewish Hospital
4.5/5(227 reviews)
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$26
per adult
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
$27
per adult
84% of travellers recommend
Explore a world of travel with Expedia
- St. Louis Hotels
- Hotels near Cathedral Basilica of St. Louis
- Hotels near World Chess Hall of Fame
- Hotels near Barnes Jewish Hospital
- Hotels near St. Louis Children's Hospital
- Hotels near Central West End Station
- Hotels near Forest Park
- Cheap Hotels in St. Louis
- Hotels near Cabanne House
- Hotels near St. Louis Science Center
- Hotels near Pagoda Circle
- Hotels near Contemporary Art Museum St. Louis
- Hotels near The Muny Theater
- Hotels near Fox Theater
- Hotels near Jewel Box
- Hotels near St. Louis University
- Hotels near DeBaliviere Place
- Hotels near St. Louis Zoo
- Hotels near Pulitzer Foundation for the Arts
- Hotels near Sheldon Concert Hall
- Hotels near Dennis and Judith Jones Visitor and Education Center
- Hotels near Grandel Theater
- Hotels near Grand Center
- Luxury Hotels in Grand Center
- Family Hotels in Grand Center
- Boutique Hotels in Grand Center
- La Quinta Inn & Suites Hotels in Grand Center
- Historic Hotels in Grand Center
- Hotels near St. Louis Symphony Orchestra
- Hotels near Powell Symphony Hall
- Hotels near Powell Hall
- Hotels near Downtown St. Louis
- Hotels near Missouri History Museum
- Hotels near Forest Park Station
- Hotels near St. Alphonsus Liguori Catholic Church
- Hotels near Chaifetz Arena
- Hotels near St. Teresa of Avila Catholic Church
- Hotels near The Hill
- Gay friendly Hotels in The Hill
- Hotels near St. Louis Art Museum
- Hotels near Busch Stadium
- Hotels near Missouri Botanical Gardens and Arboretum
- Hotels near Delmar Station
- Hotels near Shaw
- Hotels near Clayton-Tamm
- Hotels near The Gate
- Hotels near Compton Hill Reservoir Park
- Hotels with Free Airport Shuttle in St. Louis
- Hotels near Skinker Station
- Hotels near Compton Heights
- 5 Star Hotels in Compton Heights
- Hotels with Restaurants in Compton Heights
- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
- Car rentals near Cathedral Basilica of St. Louis
- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
- Mini Car Rentals near St. Louis University
- Car rentals near St. Louis Zoo
- Minivan Car Rentals near St. Louis Zoo
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.