Central West End Vacations from $289

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Your Central West End Vacation

Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.

The Latest Central West End Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
The Wildwood Hotel
The Principal Hotel
WorldMark Lake of the Ozarks
Courtyard by Marriott St. Louis Downtown/Convention Center

Where to stay in Central West End

Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End

Central West End Hotel Deals

Aloft St. Louis Cortex

Aloft St. Louis Cortex

3 out of 5
4245 Duncan Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Aug 31 to Sep 1
$133 total
Aug 31 - Sep 1
Total includes taxes and fees
8.6/10 Excellent! (727 reviews)
"Parking was a little challenging but kind staff and shuttle to garage."

Reviewed on Aug 15, 2025

Aloft St. Louis Cortex
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway, St. Louis, MO
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $262 total per night from Aug 24 to Aug 25
$262 total
Aug 24 - Aug 25
Total includes taxes and fees
8.8/10 Excellent! (1,005 reviews)
"."

Reviewed on Aug 19, 2025

The Royal Sonesta Chase Park Plaza St. Louis
The West End

The West End

2 out of 5
4215 Lindell Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $124 total per night from Sep 8 to Sep 9
$124 total
Sep 8 - Sep 9
Total includes taxes and fees
8.2/10 Very Good! (282 reviews)
"Great"

Reviewed on Aug 15, 2025

The West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Central West End

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.