Central West End Vacations from $479
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Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Save 100% on your flight
Price was $1,151, price is now $674 per person
$674
per person
Apr 29 - May 6
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
9.2/10 Wonderful! (1,620 reviews)
the hotel is very comfortable and the staff was very helpful.
Reviewed on Mar 20, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Save 100% on your flight
Price was $1,194, price is now $814 per person
$814
per person
Apr 29 - May 6
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.8/10 Excellent! (1,065 reviews)
Room was absolutely beautiful, very clean and spacious!
Reviewed on Mar 21, 2026
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
3 out of top 10 points of interest in this area
4/5(4,014 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
Hotel Indigo St Louis - Central West End by IHG
4630 Lindell St. Louis MO
Fully refundable
$144 nightly
The price is $170 total per night from Apr 5 to Apr 6
$170 total
Apr 5 - Apr 6
Total with taxes and fees
8.4/10 Very Good! (1,005 reviews)
My room was clean and bathroom spacious. The manager sent a text to guests when a weather emergency occurred to let everyone know where to go and also followed up to make sure my stay was going well
Reviewed on Mar 19, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $217 total per night from Apr 5 to Apr 6
$217 total
Apr 5 - Apr 6
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
The property was well maintained, and everybody was very helpful polite the day was phenomenal. We couldn’t ask for anything else. It was great.
Reviewed on Mar 17, 2026
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
8.2/10 Very Good! (1,002 reviews)
Everything was good.
Reviewed on Mar 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Barnes Jewish Hospital
4.5/5(228 reviews)
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Cathedral Basilica of St. Louis
4.5/5(496 reviews)
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
4/5(9 reviews)
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
Lemp Haunted Neighborhood Walking Tour
$30
per adult
84% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
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- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
- Car rentals near Cathedral Basilica of St. Louis
- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
- Mini Car Rentals near St. Louis University
- Car rentals near St. Louis Zoo
- Minivan Car Rentals near St. Louis Zoo
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.