Title: Central West End Vacation Packages 2026 from $277 | Expedia.com [Central West End Travel Guide](https://expedia.com/St-Louis-Central-West-End.dx6175135)[Hotels in Central West End](https://expedia.com/Central-West-End-St-Louis-Hotels.0-n6175135-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.com/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.com/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Car Rentals in Central West End](https://expedia.com/Car-Rentals-In-Central-West-End.d6175135.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6069379/470182f2-f462-4946-8b56-3ec5dda9861d.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Central West End Vacations from $277 ## Book a Hotel + Flight or Car together to unlock savings ## Your Central West End Vacation Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including [St. Louis Zoo](https://www.expedia.com/St-Louis-Zoo-St-Louis.d502878.Vacation-Attraction), [St. Louis Art Museum](https://www.expedia.com/St-Louis-Art-Museum-St-Louis.d502859.Vacation-Attraction) and [Cathedral Basilica of St. Louis](https://www.expedia.com/Cathedral-Basilica-Of-St-Louis-Central-West-End.d6069379.Vacation-Attraction). Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there. ## The Latest Central West End Vacation Packages Price found within the past 48 hours. Click for updated prices. ![Hilton Garden Inn Chesterfield](https://images.trvl-media.com/lodging/1000000/300000/297100/297075/c23cebe0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hilton Garden Inn Chesterfield Save 100% on your flight $277 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.2/10 Very Good! (779 reviews) Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again. Reviewed on Dec 22, 2025 ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Wildwood Hotel $353 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 9.2/10 Wonderful! (1,600 reviews) Clean room and easy parking. Reviewed on Feb 2, 2026 ![The Cheshire](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Cheshire Save 100% on your flight $362 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.6/10 Excellent! (1,002 reviews) I love the whole "English Tudor" vibe at the hotel. The room was clean and well-appointed. The staff is friendly and the hotel lounge is a fun place to unwind. Reviewed on Feb 6, 2026 ![Hotel Saint Louis, Autograph Collection](https://images.trvl-media.com/lodging/28000000/27480000/27478600/27478599/8a12cc18_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Saint Louis, Autograph Collection Downtown St. Louis Save 100% on your flight $420 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.8/10 Excellent! (458 reviews) Property and room was really nice. I will be staying here in the future Reviewed on Nov 25, 2025 ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Ameristar Casino Resort and Spa Save 100% on your flight $397 per person Apr 17 - Apr 20 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.4/10 Very Good! (1,006 reviews) The room was spotless and the employees went above and beyond for my fiancée and I. It was a wonderful stay and we look forward to staying again in the future. There is lots of food to choose from at Ameristar. Not to mention there is lots of fun to be had. We personally played the slots, ate dinner before that and after all of that we enjoyed the sparkling clean pool and hot tub at the hotel. It waa a wonderful stay and we definitely look forward to staying again. Reviewed on Feb 6, 2026 ## Where to stay in Central West End Find the best Central West End areas and neighborhoods for the activities you enjoy most. [Learn more about Central West End](https://expedia.com/St-Louis-Central-West-End.dx6175135) ![Meeting of the Waters Fountain showing a statue or sculpture and a fountain](https://images.trvl-media.com/place/553248621555612576/762dd336-6149-4976-83d5-b2545c390515.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown St. Louis 4 out of top 10 points of interest in this area 4/5(4,004 area reviews) Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River. [Find hotel + flight trips in Downtown St. Louis](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20St.%20Louis&DestID=800136&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![St. Louis Missouri](https://images.trvl-media.com/place/6058846/ad61b28c-fc90-4997-9e8c-7d09999a125f.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Clayton 1 out of top 10 points of interest in this area Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station. [Find hotel + flight trips in Clayton](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Clayton&DestID=6058846&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Soulard](https://images.trvl-media.com/place/553248634993813110/772699ae-c004-41dd-b7b2-699b703bad53.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Soulard 4/5(6 area reviews) Brewery tours, a farmers market, global restaurants, blues bars and a Mardi Gras parade make this one of the city’s liveliest neighborhoods. [Find hotel + flight trips in Soulard](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Soulard&DestID=553248634993813110&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Heading west out of St Louis found this little waterfall on a side road just a couple of miles off the Interstate. Nice stop to stretch the legs. Quick stops off the Interstate can be both interesting and refreshing.](https://images.trvl-media.com/place/3284/2b5e5af6-3144-40d5-a52e-14d114aa71d4.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown West 3 out of top 10 points of interest in this area If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing. [Find hotel + flight trips in Downtown West](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20West&DestID=553248635976473134&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Creve Coeur Lake, Saint Louis, Missouri Fall Season](https://images.trvl-media.com/place/7717/99c4d9ff-92a3-4e6a-85fa-a8b0fe6fb3f3.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Creve Coeur Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town. [Find hotel + flight trips in Creve Coeur](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Creve%20Coeur&DestID=7717&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ## Central West End Hotel Deals ![AC Hotel St. Louis Central West End](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/eba0e02e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### AC Hotel St. Louis Central West End 215 YORK AVENUE St. Louis MO Fully refundableReserve now, pay when you stay $139 nightly $164 total Feb 22 - Feb 23 Total with taxes and fees 9/10 Wonderful! (704 reviews) Room was clean nice staff Reviewed on Feb 2, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F22%2F2026&endDate=2%2F23%2F2026&selected=71082568&PinnedHotelID=71082568&HadPinnedHotel=true®ionId=6175135) ![The West End](https://images.trvl-media.com/lodging/107000000/106720000/106715700/106715696/ccf67b25_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The West End 4215 Lindell Blvd St. Louis MO Fully refundableReserve now, pay when you stay $115 nightly $131 total Feb 8 - Feb 9 Total with taxes and fees 8.4/10 Very Good! (425 reviews) The room was clean. Nothing fancy. Very small but felt cozy. Reviewed on Jan 23, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F8%2F2026&endDate=2%2F9%2F2026&selected=106715696&PinnedHotelID=106715696&HadPinnedHotel=true®ionId=6175135) ![ The Royal Sonesta Chase Park Plaza St. Louis](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Royal Sonesta Chase Park Plaza St. Louis 212 N Kingshighway St. Louis MO Fully refundableReserve now, pay when you stay $200 nightly $236 total Feb 10 - Feb 11 Total with taxes and fees 9/10 Wonderful! (1,000 reviews) The room was amazing and the staff made our stay perfect! There is so much to do at the hotel from the movie theatre to dining and drinks you really don’t have to leave. Reviewed on Jan 23, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&selected=465749&PinnedHotelID=465749&HadPinnedHotel=true®ionId=6175135) [See all 1,875 properties in Central West End](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=6175135) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ### Discover the most popular places to visit in Central West End ![Cathedral Basilica of St. Louis](https://images.trvl-media.com/place/6069379/316a31f0-468c-4ae0-8d1e-d8a43b215c69.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cathedral Basilica of St. Louis 4.5/5(493 reviews) Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style. [](https://expedia.com/Cathedral-Basilica-Of-St-Louis-Central-West-End.d6069379.Vacation-Attraction) ![St. Louis](https://images.trvl-media.com/place/553248621555612614/350cb09a-eff2-4e20-ae3a-092116f4088f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### World Chess Hall of Fame 4/5(9 reviews) Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center. [](https://expedia.com/World-Chess-Hall-Of-Fame-Central-West-End.d553248621555612614.Vacation-Attraction) #### Barnes Jewish Hospital 4.5/5(227 reviews) Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here. [](https://expedia.com/Barnes-Jewish-Hospital-Central-West-End.d6160523.Vacation-Attraction) ### Things to do ![St. Louis: Gateway Ghouls and Hauntings Walking Tour](https://mediaim.expedia.com/localexpert/47668485/dd78fc5b-2837-423e-80a2-c4dfd8151a08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Ghost Tour: Sinister Sins & Shadows $32 per adult [](https://expedia.com/things-to-do/st-louis-ghost-tour-sinister-sins-shadows.a47668485.activity-details) ![St. Louis Premium Driving Tour with Boat Ride & Arch](https://mediaim.expedia.com/localexpert/47712556/5e48de69-a78b-4315-bccd-6ae9dafd98a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Driving Tour with Boat Ride & Arch $174 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/st-louis-premium-driving-tour-with-boat-ride-arch.a47712556.activity-details) ![Best of St. Louis Small Group Tour w/ Arch & River Cruise](https://mediaim.expedia.com/localexpert/46051486/4ca2bb68-86bc-4a3d-a7eb-e432157373a3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### St. Louis Premium Small Group Tour With Arch & River Cruise $169 per adult **84%** of travellers recommend [](https://expedia.com/things-to-do/st-louis-premium-small-group-tour-with-arch-river-cruise.a46051486.activity-details) [See all activities in St. Louis](https://expedia.com/things-to-do/search?rid=6175135) ## Explore a world of travel with Expedia - 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