Central West End Vacations from $478

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Your Central West End Vacation

Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.

The Latest Central West End Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
The Wildwood Hotel
Hotel Saint Louis, Autograph Collection
Ameristar Casino Resort and Spa

Where to stay in Central West End

Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End

Central West End Hotel Deals

 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $205 total per night from Mar 8 to Mar 9
$205 total
Mar 8 - Mar 9
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
Although the building appears older, it is very well maintained and overall extremely clean. The interior design of the hotel is also impressive. Our room was condominium-style with a separate bedroom, which made the stay very comfortable. It included a small kitchen with basic cooking equipment ...

Reviewed on Feb 23, 2026

The Royal Sonesta Chase Park Plaza St. Louis
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

3.5 out of 5
4630 Lindell St. Louis MO
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $151 total per night from Mar 8 to Mar 9
$151 total
Mar 8 - Mar 9
Total with taxes and fees
8.2/10 Very Good! (1,008 reviews)
Great location

Reviewed on Mar 2, 2026

Hotel Indigo St Louis - Central West End by IHG
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $138 total per night from Mar 4 to Mar 5
$138 total
Mar 4 - Mar 5
Total with taxes and fees
8.6/10 Excellent! (440 reviews)
Very welcoming staff, hotel was clean

Reviewed on Mar 2, 2026

The West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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