Central West End Vacations from $523
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Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Home2 Suites by Hilton St. Louis Downtown
Downtown West
Price was $660, price is now $523 per person
$523
per person
Apr 21 - Apr 24
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to St. Louis (STL)
8/10 Very Good! (696 reviews)
I love this hotel. The breakfast ❤️ I checked out but my daughter still have games, they kept our luggage safe till we are done for the day
Reviewed on Mar 15, 2026
The Wildwood Hotel
Price was $686, price is now $538 per person
$538
per person
May 23 - May 25
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
9.2/10 Wonderful! (1,620 reviews)
What a pleasant surprise! This area and lovely hotel was wonderful! The room was beautiful. The only negative was the elevator. It was small and it took a while at checkout time.
Reviewed on Mar 16, 2026
The Westin St. Louis
Downtown St. Louis
Price was $675, price is now $554 per person
$554
per person
Apr 21 - Apr 24
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
We stayed 3 nights and the property refused to provide towels and washcloths until 11pm on the last night
Reviewed on Mar 15, 2026
Ameristar Casino Resort and Spa
Price was $866, price is now $713 per person
$713
per person
Apr 28 - May 2
found 7 hours ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
Room was clean and very nice! Casino was nice. We didn’t use the spa or weight room.
Reviewed on Mar 16, 2026
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
4 out of top 10 points of interest in this area
4/5(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
Hotel Indigo St Louis - Central West End by IHG
4630 Lindell St. Louis MO
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $146 total per night from Apr 5 to Apr 6
$146 total
Apr 5 - Apr 6
Total with taxes and fees
8.4/10 Very Good! (1,004 reviews)
This hotel was in an excellent location. The staff was efficient and attentive. Our only complaint was the food in the onsite restaurant, the BelAir Social. The food was edible, but nothing special for the price. The service was subpar at best. We were sitting at the bar and had to request service ...
Reviewed on Mar 15, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
$184 nightly
The price is $217 total per night from Apr 5 to Apr 6
$217 total
Apr 5 - Apr 6
Total with taxes and fees
9/10 Wonderful! (1,004 reviews)
We were not told about the $15 credit. We were also overcharged both for the remaining balance and for a meal in one of their restaurants. We were not given any receipt or told that we would be charged a different amount, also our $15 credit was not removed. Only after looking at my credit card statement ...
Reviewed on Mar 16, 2026
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Apr 5 to Apr 6
$149 total
Apr 5 - Apr 6
Total with taxes and fees
8.2/10 Very Good! (1,005 reviews)
Location is good for access to Barnes Hospital and Center for Advanced Medicine. There is an adjacent Applebee's restaurant. The breakfast is not a great value, overpriced for fare that is free at most 3 star hotels. Parking costs about $16 per night. Room was adequate but not up to Hilton standards. ...
Reviewed on Mar 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Barnes Jewish Hospital
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Cathedral Basilica of St. Louis
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
St. Louis Premium Small Group Tour With Arch & River Cruise
$169
per adult
84% of travellers recommend
Explore a world of travel with Expedia
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- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
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- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.