Central West End Vacations from $177
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Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Saint Louis, Autograph Collection
Downtown St. Louis
Save 100% on your flight
Price was $331, price is now $231 per person
$231
per person
Apr 7 - Apr 9
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (476 reviews)
Great Luxury Hotel and location.
Reviewed on Mar 4, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Save 100% on your flight
Price was $252, price is now $180 per person
$180
per person
Apr 7 - Apr 9
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,056 reviews)
The property was beautiful and unique. The food was a disappointment. Unfortunately it was just too greasy for us.
Reviewed on Mar 6, 2026
Crowne Plaza St. Louis Airport by IHG
Price was $610, price is now $486 per person
$486
per person
Apr 30 - May 4
found 1 day ago
Roundtrip flight included
Mesa (AZA) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)
Everything was amazing but parking was not enough. We had to park on ur median. Rooms are older but still nice. Good area. Friendly staff.
Reviewed on Feb 21, 2026
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
3 out of top 10 points of interest in this area
4/5(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $205 total per night from Mar 15 to Mar 16
$205 total
Mar 15 - Mar 16
Total with taxes and fees
9/10 Wonderful! (1,002 reviews)
This hotel was beautiful! Well maintained great staff, except for the valet team who was very rude
Reviewed on Mar 4, 2026
Hotel Indigo St Louis - Central West End by IHG
4630 Lindell St. Louis MO
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $146 total per night from Mar 15 to Mar 16
$146 total
Mar 15 - Mar 16
Total with taxes and fees
8.2/10 Very Good! (1,009 reviews)
Great location
Reviewed on Mar 2, 2026
The West End
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $117 total per night from Mar 18 to Mar 19
$117 total
Mar 18 - Mar 19
Total with taxes and fees
8.6/10 Excellent! (441 reviews)
Very welcoming staff, hotel was clean
Reviewed on Mar 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Barnes Jewish Hospital
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Cathedral Basilica of St. Louis
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
Lemp Haunted Neighborhood Walking Tour
$30
per adult
84% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
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- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
- Car rentals near Cathedral Basilica of St. Louis
- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
- Mini Car Rentals near St. Louis University
- Car rentals near St. Louis Zoo
- Minivan Car Rentals near St. Louis Zoo
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.