Central West End Vacations from $201
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Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
Save 100% on your flight
Price was $285, price is now $201 per person
$201
per person
Feb 27 - Mar 2
found 23 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.
Reviewed on Dec 22, 2025
White House at Grand Central
Grand Center
Save 100% on your flight
Price was $665, price is now $416 per person
$416
per person
Mar 25 - Mar 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (123 reviews)
Very clean and very friendly people
Reviewed on Nov 11, 2025
Home2 Suites by Hilton St. Louis Downtown
Downtown West
Save 100% on your flight
Price was $995, price is now $706 per person
$706
per person
Mar 25 - Mar 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8/10 Very Good! (567 reviews)
The hotel and the room were very up-to-date, clean and inviting, the staff including the security guards (James, Norris and Mike) were all very professional, full of information about the area, restaurants and sights. They all went out of their way to help us and were so friendly. The breakfast was changing every day and better than your normal hotel breakfast. And the hotel was convenient to everything downtown
Reviewed on Jan 12, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Save 100% on your flight
Price was $769, price is now $551 per person
$551
per person
Mar 25 - Mar 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
I always love staying Angad art hotel!
Reviewed on Jan 11, 2026
Where to stay in Central West End
Find the best Central West End areas and neighborhoods for the activities you enjoy most. Learn more about Central West End
Downtown St. Louis
4 out of top 10 points of interest in this area
4/5(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals
AC Hotel St. Louis Central West End
215 YORK AVENUE St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Jan 23 to Jan 24
$159 total
Jan 23 - Jan 24
Total with taxes and fees
9/10 Wonderful! (691 reviews)
Very friendly, great parking. Beautiful rooms.
Reviewed on Jan 8, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $208 total per night from Jan 25 to Jan 26
$208 total
Jan 25 - Jan 26
Total with taxes and fees
9/10 Wonderful! (1,004 reviews)
Spotless room and a beautiful property.
Reviewed on Jan 12, 2026
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $144 total per night from Jan 24 to Jan 25
$144 total
Jan 24 - Jan 25
Total with taxes and fees
8.2/10 Very Good! (1,001 reviews)
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Reviewed on Jan 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Central West End
Cathedral Basilica of St. Louis
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.
World Chess Hall of Fame
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Barnes Jewish Hospital
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
$169
per adult
84% of travellers recommend
Explore a world of travel with Expedia
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- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
- St. Louis Vacations
- Turtle Playground
- Scott Joplin House State Historic Site
- Washington Avenue Historic District
- Tower Grove Park
- Fairgrounds Park
- Anheuser-Busch Brewery
- Tivoli Theatre
- St. Louis Walk of Fame
- Messiah Lutheran Church
- St. Louis Union Station Mini Golf
- Visit Compton Heights
- Car rentals near St. Louis
- Car rentals near Cathedral Basilica of St. Louis
- Car rentals near World Chess Hall of Fame
- Car rentals near Barnes Jewish Hospital
- Car rentals near Forest Park
- Car rentals near Ellen Clark Sculpture Park
- Car rentals near St. Louis University
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- Car rentals near St. Louis Zoo
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.