
Central West End Vacations from $289
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Your Central West End Vacation
Whatever your style of travel, you can see and do more with a tailor-made Central West End vacation package. Spend your break enjoying this neighborhood's shopping and its other charms. When it's time to head out and explore, you'll find lots of big-name attractions nearby including St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Visit one, two or more during your trip to Central West End. Stop daydreaming and start doing. When it's time to lock in your vacation to Central West End, Expedia will help get you there.
The Latest Central West End Vacation Packages

Hilton Garden Inn Chesterfield
Reviewed on Jul 26, 2025

The Wildwood Hotel
Reviewed on Aug 19, 2025

The Principal Hotel
Reviewed on Aug 18, 2025

WorldMark Lake of the Ozarks
Reviewed on Aug 10, 2025
Where to stay in Central West End

Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Central West End Hotel Deals

Aloft St. Louis Cortex
Reviewed on Aug 15, 2025

The Royal Sonesta Chase Park Plaza St. Louis
Reviewed on Aug 19, 2025

The West End
Reviewed on Aug 15, 2025
Discover the most popular places to visit in Central West End

Cathedral Basilica of St. Louis
Marvel at the vast collection of mosaic art that beautifies the interior of this colossal cathedral built in the Romanesque Revival style.

World Chess Hall of Fame
Play a game of chess on a giant outdoor board, inspect chess-related artifacts and view artworks inspired by the two-player board game at this fascinating center.
Barnes Jewish Hospital
Though Barnes Jewish Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Louis while you are here.
Things to do

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

Best of St. Louis Small Group Tour w/ Arch & River Cruise

St. Louis: Guided Small Group City Tour with River Cruise
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- Cathedral Basilica of St. Louis
- World Chess Hall of Fame
- St. Louis Zoo
- Barnes Jewish Hospital
- The Muny Theater
- Jewel Box
- Cabanne House
- St. Louis Art Museum
- Pagoda Circle
- Contemporary Art Museum St. Louis
- Fox Theater
- Bruno David Gallery
- Pulitzer Foundation for the Arts
- Sheldon Concert Hall
- Missouri History Museum
- Grandel Theater
- St. Louis University
- St. Louis Symphony Orchestra
- Powell Hall
- St. Alphonsus Liguori Catholic Church
- Missouri Botanical Gardens and Arboretum
- Chaifetz Arena
- Visit Grand Center
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- Messiah Lutheran Church
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- Visit Compton Heights
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