Find all hotels by Independent in Clayton, MO from $70
Check prices for these dates
Our top choices for Clayton Independent
7.6 out of 10, Good, (1265)
"location attentive staff large king room"
Stephen
$89 nightly
The price is $104
Dec 14 - Dec 15
Total with taxes and fees
8.8 out of 10, Excellent, (3032)
"Clean room, good breakfast and good location "
Martin
$90 nightly
The price is $105
Dec 21 - Dec 22
Total with taxes and fees
8.6 out of 10, Excellent, (1003)
"Excellent place to stay. "
Todd
$127 nightly
The price is $151
Dec 17 - Dec 18
Total with taxes and fees
6.6 out of 10, (1004)
"Great place to stay "
Askar
$60 nightly
The price is $70
Dec 29 - Dec 30
Total with taxes and fees
7.6 out of 10, Good, (1970)
"Clean room, friendly staff, lobby was nice and welcoming. "
Tricia
$99 nightly
The price is $115
Dec 14 - Dec 15
Total with taxes and fees
9.2 out of 10, Wonderful, (1607)
"Great place!"
Biju
$95 nightly
The price is $111
Dec 16 - Dec 17
Total with taxes and fees
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport WestMaryland Heights
7.4 out of 10, Good, (1000)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
Jen
$64 nightly
The price is $74
Jan 5 - Jan 6, 2026
Total with taxes and fees
9.0 out of 10, Wonderful, (1913)
"Great service, unique hotel. Would absolutely stay again!"
Michael
$148 nightly
The price is $176
Dec 14 - Dec 15
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Clayton Hotel Reviews
21C Museum Hotel St Louis
10/10 Excellent
Find out more about Clayton
Clayton, St. Louis Hotel Guide
St. Louis is an important city in United States of America. It has a nice range of interesting neighborhoods and communities to explore, such as Clayton, which is approximately 9 miles to the west of downtown St. Louis.
Make time to visit the Gateway Arch, a famous tourist attraction in St. Louis.
Shop until you can shop no more at Saint Louis Galleria Mall, where you will be able to buy almost anything you're looking for, from clothes and shoes to general supplies. Avoid the anxiety of a long journey in a foreign city by staying right by this attraction. The Ritz-Carlton, St. Louis and Residence Inn by Marriott St. Louis Galleria are just two hotels you can choose from.
Follow the sweet smell of freshly brewed coffee to Auntie Anne's Pretzels, a popular Clayton pit-stop where you can enjoy a revitalizing break. Once you've really worked up an appetite, Truffles is an excellent choice for dinner. When darkness falls, kick off a lively evening with the friendly locals at Helium Comedy Club - St. Louis.
Accommodation options near Clayton
If you are looking for more accommodation options, you could check out Expedia's Brentwood hotels guide. Brentwood lies 2 miles to the southeast of central Clayton. Alternatively, you could check out Expedia's Richmond Heights hotels guide for hotels in Richmond Heights, another St. Louis neighborhood.Expedia wishes you and your traveling companions many fun-filled moments in St. Louis. For more fun things to check out here, pop across to our St. Louis vacation travel guide. And when it's time to find a hotel, go to our St. Louis hotels page.
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