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Guest Houses in Defiance

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Recommended hotels in Defiance

WoodSpring Suites St Peters-OFallon

2.5 star property
St. Peters
10.0 out of 10, Exceptional, (14)
"Very nice:) "
United States
Alicia
$74 nightly
The price is $85
Dec 3 - Dec 4
Total with taxes and fees
WoodSpring Suites St Peters-OFallon

Hampton Inn St. Charles St. Peters

2.5 star property
St. Charles
8.0 out of 10, Very Good, (1021)
"Room was very clean. Staff were nice."
United States
Susann
$87 nightly
The price is $100
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn St. Charles St. Peters

The Wildwood Hotel

3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1613)
"Great hotel in a great neighborhood "
United States
Linda
$95 nightly
The price is $111
Dec 7 - Dec 8
Total with taxes and fees
The Wildwood Hotel

Comfort Inn & Suites St. Louis - O'Fallon

2.5 star property
O'Fallon
7.6 out of 10, Good, (1008)
"Great front desk experience, no issues booking same day!"
United States
Tracy
$73 nightly
The price is $86
Jan 1 - Jan 2, 2026
Total with taxes and fees
Comfort Inn & Suites St. Louis - O'Fallon

Hollywood Casino & Hotel St. Louis

3.5 star property
Maryland Heights
8.4 out of 10, Very Good, (2219)
"Decent room. Well priced and centrally located for out soccer tournament we were in town for"
United States
Travis
$89 nightly
The price is $104
Dec 15 - Dec 16
Total with taxes and fees
Hollywood Casino & Hotel St. Louis

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3.0 star property
Maryland Heights
7.4 out of 10, Good, (1016)
"Everthing was great"
United States
Takashi
$55 nightly
The price is $64
Dec 16 - Dec 17
Total with taxes and fees
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Quality Inn

2.5 star property
Foristell
8.2 out of 10, Very Good, (902)
"Easy check in and out, the staff is very nice and professional. I would stay there any time Im in the area and need a room. Highly recommended."
United States
Ivaylo
$84 nightly
The price is $95
Dec 21 - Dec 22
Total with taxes and fees
Quality Inn

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
Fenton
8.0 out of 10, Very Good, (1030)
"Very friendly staff "
United States
Amber
$85 nightly
The price is $98
Dec 7 - Dec 8
Total with taxes and fees
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Holiday Inn Express & Suites Wentzville St Louis West by IHG

2.5 star property
Wentzville
9.4 out of 10, Exceptional, (829)
"Good all around stay "
United States
Chad
$103 nightly
The price is $124
Jan 2 - Jan 3, 2026
Total with taxes and fees
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Courtyard by Marriott St. Louis Chesterfield

3.0 star property
Chesterfield
9.0 out of 10, Wonderful, (574)
"Very clean hotel with great staff "
United States
brad
$84 nightly
The price is $98
Dec 26 - Dec 27
Total with taxes and fees
Courtyard by Marriott St. Louis Chesterfield

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
O'Fallon
8.8 out of 10, Excellent, (1020)
"Nice breakfast, friendly staff"
United States
Damon
$88 nightly
The price is $104
Jan 1 - Jan 2, 2026
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive

Super 8 by Wyndham Washington

2.0 star property
Washington
8.4 out of 10, Very Good, (696)
"The staff was extremely nice & accommodating."
United States
Brenda
$85 nightly
The price is $96
Dec 8 - Dec 9
Total with taxes and fees
Super 8 by Wyndham Washington

Drury Inn & Suites Southwest St. Louis

3.0 star property
Valley Park
9.4 out of 10, Exceptional, (1012)
"Clean room, breakfast, and friendly staff"
United States
Angie
$119 nightly
The price is $139
Dec 7 - Dec 8
Total with taxes and fees
Drury Inn & Suites Southwest St. Louis

Cedar Creek

3.0 star property
New Haven
9.0 out of 10, Wonderful, (258)
"The room was spotless and the bed was very comfortable. The screened in patio that our cabin room had was perfect for sitting outside and enjoying the fall weather. All the staff that we encountered were extremely friendly and helpful. They even got us out of a jam when we needed a corkscrew for our wine. The drive into Herman was not an issue at all and we have already talked about wanting to come back."
United States
Phillip
$126 nightly
The price is $135
Dec 9 - Dec 10
Total with taxes and fees
Cedar Creek

Baymont by Wyndham Warrenton

2.5 star property
Warrenton
7.4 out of 10, Good, (1004)
"Great service and nice rooms. 5 Star staff as well. Over all a great experience! "
United States
Justin
$84 nightly
The price is $96
Dec 8 - Dec 9
Total with taxes and fees
Baymont by Wyndham Warrenton

Drury Plaza Hotel St. Louis Chesterfield

3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1034)
"Great place to stay! "
United States
Stephanie
$130 nightly
The price is $151
Dec 7 - Dec 8
Total with taxes and fees
Drury Plaza Hotel St. Louis Chesterfield

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1020)
"Love this hotel. "
United States
Lisa
$118 nightly
The price is $135
Jan 1 - Jan 2, 2026
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn Near Six Flags St. Louis

2.5 star property
Pacific
8.4 out of 10, Very Good, (866)
"Staff was absolutely incredible!! Very accommodating and super sweet ladies at check in. Coffee was amazing! And beds were super comfy!!"
United States
Natalia
$90 nightly
The price is $103
Dec 29 - Dec 30
Total with taxes and fees
Comfort Inn Near Six Flags St. Louis

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
O'Fallon
8.6 out of 10, Excellent, (828)
"The staff was so friendly and helpful! The hotel was exceptionally clean. Breakfast was very good with lots of variety!"
United States
Millie
$95 nightly
The price is $112
Dec 4 - Dec 5
Total with taxes and fees
Holiday Inn Express St. Louis West - O'Fallon by IHG

Comfort Suites St Charles - St Louis

2.5 star property
St. Charles
8.4 out of 10, Very Good, (1015)
"The staff was friendly "
United States
natalie
$88 nightly
The price is $101
Dec 21 - Dec 22
Total with taxes and fees
Comfort Suites St Charles - St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Guest Houses information

Number of reviews
18,909
Accommodation
1 Guest Houses
Lowest Price
$64
Highest Price
$151

Frequently asked questions

What is the nightly rate for a guest house in Defiance?
Rates for Defiance guest houses vary, but travelers can find great-value prices from $64 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Defiance guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Defiance guest house and a B&B?
A guest house in Defiance is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

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