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Our top choices for Defiance motels

1. Americas Best Inn - Eureka
Americas Best Inn - EurekaEureka
6.4 out of 10, (161 reviews)
$73 nightly
The price is $85
Nov 8 - Nov 9
Total with taxes and fees

2. Relax Inn Saint Charles
Relax Inn Saint CharlesSt. Charles
6.8 out of 10, (1,003 reviews)
$63 nightly
The price is $72
Nov 6 - Nov 7
Total with taxes and fees

3. Motel 6 Maryland Heights, MO
Motel 6 Maryland Heights, MOWestport
6.2 out of 10, (1,001 reviews)
$65 nightly
The price is $76
Nov 6 - Nov 7
Total with taxes and fees

4. Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.8 out of 10, Good, (1,000 reviews)
$84 nightly
The price is $96
Nov 29 - Nov 30
Total with taxes and fees

5. Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (682 reviews)
$78 nightly
The price is $89
Dec 6 - Dec 7
Total with taxes and fees

6. BEST WAY INN
BEST WAY INNBridgeton
6.4 out of 10, (27 reviews)
$69 nightly
The price is $84
Nov 15 - Nov 16
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.



















