Des Moines Vacation Rentals

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Our top choices for Des Moines vacation rentals

Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking

Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking
Downtown Des Moines
10.0 out of 10, Exceptional, (25)
"Had a great time thank you"
United States
Dixie
$139 nightly
The price is $156
Dec 14 - Dec 15
Total with taxes and fees
Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking

Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!

Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!
Downtown Des Moines
10.0 out of 10, Exceptional, (2)
"No issues, everything went very smoothly. Second tv in bedroom is nice if you like watching TV in bed"
United States
Kevin B.
$136 nightly
The price is $149
Dec 16 - Dec 17
Total with taxes and fees
Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!

Sleepover: Extraordinary Studio + Gym- Des Moines

Sleepover: Extraordinary Studio + Gym- Des Moines
Drake
10.0 out of 10, Exceptional, (3)
"Nice place and close to where we needed to be. "
United States
Lori P.
$158 nightly
The price is $177
Dec 14 - Dec 15
Total with taxes and fees
Sleepover: Extraordinary Studio + Gym- Des Moines

Quiet Studio on Grand Ave - Heart of Downtown

Quiet Studio on Grand Ave - Heart of Downtown
Downtown Des Moines
9.4 out of 10, Exceptional, (6)
"Property was in a good location, street parking was very easy. Host was incredibly responsive and helpful. "
United States
Cameron W.
$935 nightly
The price is $955
Dec 14 - Dec 15
Total with taxes and fees
Quiet Studio on Grand Ave - Heart of Downtown

Spacious Studio Unit in Des Moines

Spacious Studio Unit in Des Moines
Downtown Des Moines
9.0 out of 10, Wonderful, (2)
"We really enjoyed our stay at this cute little Studio in Des Moines. The location is great - right next to the Capital and Interstate. Will be back again soon :)"
United States
Amber V.
$113 nightly
The price is $124
Dec 15 - Dec 16
Total with taxes and fees
Spacious Studio Unit in Des Moines

Your home away from home

Your home away from home
Downtown Des Moines
9.0 out of 10, Wonderful, (2)
"Had a good stay, the place was very nice. Only thing that was somewhat annoying was the parking situation since we got blocked by the train many times from getting to our car. Otherwise everything was excellent!"
United States
kylee
$136 nightly
The price is $149
Dec 16 - Dec 17
Total with taxes and fees
Your home away from home

Family-Friendly 2BR with Amenities, WiFi & Parking

Family-Friendly 2BR with Amenities, WiFi & Parking
2.0 star property
Downtown Des Moines
$136 nightly
The price is $149
Dec 15 - Dec 16
Total with taxes and fees
Family-Friendly 2BR with Amenities, WiFi & Parking

Chic Des Moines 1BR with Amenities & Prime Location

Chic Des Moines 1BR with Amenities & Prime Location
2.0 star property
Downtown Des Moines
$128 nightly
The price is $140
Dec 21 - Dec 22
Total with taxes and fees
Chic Des Moines 1BR with Amenities & Prime Location

City Oasis 2br w/ Skyline Views

City Oasis 2br w/ Skyline Views
Downtown Des Moines
9.6 out of 10, Exceptional, (27)
"Location was perfect for what we were looking for! Dan was wonderful about getting back to us with any of our questions! "
United States
Kristen L.
$165 nightly
The price is $175
Dec 14 - Dec 15
Total with taxes and fees
City Oasis 2br w/ Skyline Views

Kasa Downtown Des Moines

Kasa Downtown Des Moines
4.0 star property
Downtown Des Moines
9.2 out of 10, Wonderful, (111)
"Our stay in downtown Des Moines was for an entire week. This Kasa rental worked very well for us. It was nice having the extra things like kitchen, laundry, living room, game room, etc. that you don't get staying in a hotel. Our room was located in a noisy spot. We heard the garage doors open and close often. We were also awakened by the garage pickup. Still, it was a good value and great location for us."
United States
Marie
$164 nightly
The price is $184
Dec 21 - Dec 22
Total with taxes and fees
Kasa Downtown Des Moines

Modern Studio - walk to Wells Fargo Arena

Modern Studio - walk to Wells Fargo Arena
Downtown Des Moines
9.0 out of 10, Wonderful, (8)
"The location was perfect for the Iowa Events Center. Good apartment, and very clean."
United States
Hugo M.
$947 nightly
The price is $968
Dec 14 - Dec 15
Total with taxes and fees
Modern Studio - walk to Wells Fargo Arena

Boho Loft / Skyline View / Walk to Arena Events

Boho Loft / Skyline View / Walk to Arena Events
Downtown Des Moines
10.0 out of 10, Exceptional, (6)
"Wonderful location! "
United States
Travis
$159 nightly
The price is $178
Dec 15 - Dec 16
Total with taxes and fees
Boho Loft / Skyline View / Walk to Arena Events

Skyline Serenity 2BR/2BA with Stunning City Views

Skyline Serenity 2BR/2BA with Stunning City Views
2.0 star property
Downtown Des Moines
9.8 out of 10, Exceptional, (7)
"Was a great place to stay with my girlfriends for a concert at the Casey's center - very walkable & close to many bars and food places. Liked the games in community room in the basement! Would definitely stay again. "
United States
Angela
$163 nightly
The price is $173
Dec 14 - Dec 15
Total with taxes and fees
Skyline Serenity 2BR/2BA with Stunning City Views

Modern 2BR Apartment Near Des Moines Attractions

Modern 2BR Apartment Near Des Moines Attractions
2.0 star property
Downtown Des Moines
$136 nightly
The price is $149
Dec 15 - Dec 16
Total with taxes and fees
Modern 2BR Apartment Near Des Moines Attractions

Sleepover: Attractive Studio and Gym - Des Moines

Sleepover: Attractive Studio and Gym - Des Moines
Drake
10.0 out of 10, Exceptional, (2)
"Clean and quiet for our stay. "
United States
Jackie
$158 nightly
The price is $177
Dec 18 - Dec 19
Total with taxes and fees
Sleepover: Attractive Studio and Gym - Des Moines

Stunning Downtown Studio with Rooftop Patio

Stunning Downtown Studio with Rooftop Patio
Downtown Des Moines
10.0 out of 10, Exceptional, (2)
"Just as advertised. Great communication and location. Plan to stay again during a future visit to the area."
United States
Ron D.
$951 nightly
The price is $972
Dec 14 - Dec 15
Total with taxes and fees
Stunning Downtown Studio with Rooftop Patio

Sleepover: Charming 1BD/1BA - Downtown Des Moines

Sleepover: Charming 1BD/1BA - Downtown Des Moines
Woodland Heights
10.0 out of 10, Exceptional, (1)
"Convenient to Sherman Hill and downtown. Quiet. "
United States
Abby H.
$184 nightly
The price is $206
Jan 4 - Jan 5, 2026
Total with taxes and fees
Sleepover: Charming 1BD/1BA - Downtown Des Moines

Downtown Loft Livin` | 2BD/2BR - Downtown DSM

Downtown Loft Livin` | 2BD/2BR - Downtown DSM
Downtown Des Moines
9.8 out of 10, Exceptional, (34)
"Family took a quick trip to Des Moines and had a great time. Condo was great and lots to do close by! "
United States
Crystal A.
$154 nightly
The price is $163
Dec 18 - Dec 19
Total with taxes and fees
Downtown Loft Livin` | 2BD/2BR - Downtown DSM

Stylish Urban Loft | 2BR/2BA - Heart of Downtown!

Stylish Urban Loft | 2BR/2BA - Heart of Downtown!
Downtown Des Moines
9.6 out of 10, Exceptional, (11)
"Great place!"
United States
Rachael S.
$165 nightly
The price is $167
Dec 15 - Dec 16
Total with taxes and fees
Stylish Urban Loft | 2BR/2BA - Heart of Downtown!

Central Comfort - Downtown Studio - Near Court Ave

Central Comfort - Downtown Studio - Near Court Ave
Downtown Des Moines
8.8 out of 10, Excellent, (9)
"Great spot close to everything especially for the price "
United States
James G.
$130 nightly
The price is $138
Dec 15 - Dec 16
Total with taxes and fees
Central Comfort - Downtown Studio - Near Court Ave
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Des Moines Hotel Reviews

Find out more about Des Moines

Everything you need to know about Des Moines vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Des Moines vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Des Moines vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Des Moines vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Des Moines. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Des Moines in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $139 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Des Moines rentals

At Expedia, we put the best Des Moines vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Des Moines rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Des Moines vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Des Moines. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Des Moines?

Yes, you can find vacation rentals in Des Moines close to Science Center of Iowa, or you can choose a secluded option if you're looking for extra privacy while you relax. Travelers who like culture and the arts give Des Moines high marks for its lively festivals and great live music. Leave some time to check out the acclaimed theater scene and top-notch restaurants during your visit.

What are some of the best vacation home rentals that Des Moines has to offer?

AMAZING & A PARTY BARN… HOT TUB, PL TBl, PNG PNG, & ARCADE! ACCESS TO POOLS!: Visitors give good reviews to this Des Moines vacation home rental, which offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation. Some other top choices in Des Moines are Beautiful home minutes from downtown! and SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!.

How many vacation rentals are there in Des Moines?

With 258 Expedia vacation rentals, you're sure to find just the right place for your Des Moines stay.

What’s there to see and do in Des Moines?

Enjoy the outdoors at Greater Des Moines Botanical Garden and John and Mary Pappajohn Sculpture Park, or simply take in cultural attractions like Wooly's and Science Center of Iowa. Des Moines Civic Center and Casey's Center are other places to visit while you're in town.

What’s a vacation rental in Des Moines like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Des Moines. Vacation rentals offer extras such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for small groups.