Plan your trip

An aerial view of a city with a prominent building featuring a golden dome and green-topped towers.

Des Moines Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

  • Check prices for these dates

    Check prices for these dates, December 13 – 14, 2026

    View in a map

    Our top choices for Des Moines vacation rentals

    1. Kasa Downtown Des Moines

    A modern kitchen with a central island, bar stools, stainless steel appliances, and pendant lighting.

    2. Emerald Haven

    A compact living space with a bed, a sofa, a small round table, and a potted plant.

    3. The Pink Pearl

    An outdoor patio with a wooden wall, glass sliding doors, and seating areas including a table and chairs.

    4. Tranquil Escape

    Property grounds

    5. Azure Oasis Studio

    An outdoor patio with a wooden wall, glass sliding doors, and seating areas including a table and chairs.

    6. Evergreen Nook

    A modern living room with a green sofa, a glass coffee table, and green chairs. There is a sliding glass door leading to a balcony.

    7. Central Comfort - Downtown Studio - Near Court Ave

    A modern hotel room with a bed, a desk, a TV, and large windows.

    8. The Cartier Lux DT Apt w/Skyline View

    A modern kitchen with stainless steel appliances, a dining area with a view, and a large window.

    9. Aqua Loft

    A bedroom with a bed, a green sofa, a small table, and a potted plant.

    10. Cozy Boho-Chic Downtown 2BD/2BR - Downtown DSM

    A modern living room with a black sofa, round coffee table, and a green wall with a 'Welcome' sign.

    11. Downtown Dream 2br w/ City Views 2 blocks to Court

    A living room with a sofa, coffee table, TV, and large windows with city views.

    12. Boho Loft / Skyline View / Walk to Arena Events

    A modern living room with a sofa, a coffee table, and a large plant. There is a kitchen in the background with cabinets and appliances.

    13. Sherman Hill Hide-a-way

    A compact kitchen with a central island, a dining area with a sofa and chairs, and a living room with a couch and a coffee table.

    14. Cognac Loft

    A modern apartment with a kitchen, dining area, and a large gray sectional sofa.

    15. Casa Marigold

    A modern kitchen with a central island, two pendant lights, and a dishwasher.

    16. Urban Jungle Retreat

    A modern bedroom with a bed, a sofa, and a TV.

    17. Near Wells Fargo, King Bed and Balcony and washer dryer, fitness room, Fireplace

    A modern living room with a blue sofa, a dining area with bar stools, a kitchen with a microwave, and a ceiling fan.

    18. Cedar Suite

    A modern kitchen with a black refrigerator, wooden cabinets, and a green wall with a vertical garden.

    19. Sleepover | Classic Studio and Gym - Des Moines

    An outdoor patio with a fire pit, seating, and a grill area.

    20. City Oasis 2br w/ Skyline Views

    A modern kitchen with a central island, bar stools, and a dining area with a sofa and coffee table.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

    View all properties

    Find vacation rentals that suit your style

    Cabins

    Apartments

    Aparthotels

    Condos

    Condo · s

    Cottages

    Top Des Moines Hotel Reviews

    Hotel Fort Des Moines, Curio Collection by Hilton

    A spacious lobby with high ceilings, large windows, and a chandelier.

    Baymont by Wyndham Des Moines Airport

    A sunroom with a glass ceiling, wicker furniture, and potted plants.

    Home2 Suites by Hilton Des Moines at Drake University

    An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

    Homewood Suites by Hilton Des Moines Airport

    A modern hotel lobby with a round coffee table, sofas, and a TV mounted on the wall.

    Hyatt Place Altoona/Des Moines

    An outdoor seating area with sofas and tables, stone pillars, and a pathway leading to a building.

    Surety Hotel, Autograph Collection

    A modern bar with wooden shelves and a long counter.

    Fairfield Inn & Suites Des Moines Altoona

    A hotel with a reflection in a calm body of water, surrounded by open fields.

    Holiday Inn Express & Suites Des Moines Downtown by IHG

    An indoor swimming pool with clear water, a no diving sign, and a pool ladder.

    Drury Inn & Suites West Des Moines

    An indoor swimming pool with a 30 ft depth sign, a reception area, and a 'No Lifeguard' warning sign.

    Staybridge Suites Des Moines Downtown by IHG

    A modern building with a sign that reads 'Staybridge Suites.' It features a mix of glass and brick facades, large windows, and a flat roof.

    Tru By Hilton Norwalk Des Moines

    A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.

    Tru By Hilton Grimes Des Moines

    A modern lounge area with a grey sofa, red chairs, and round tables.

    La Quinta Inn & Suites by Wyndham Johnston

    A spacious indoor area with a long wooden table, several chairs, a fireplace, and a view through large windows.

    La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

    A La Quinta hotel with a modern design, featuring a prominent sign, a covered entrance, and a brick facade.

    Find out more about Des Moines

    Everything you need to know about Des Moines vacation rentals

    Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Des Moines vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

    There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Des Moines vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

    Des Moines vacation rentals: An excellent choice for every season

    Whenever you want to travel, a warm welcome awaits you in Des Moines. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Des Moines in high season.

    Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $114 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

    How to find incredible deals on Des Moines rentals

    At Expedia, we put the best Des Moines vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

    To find some top Des Moines rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Des Moines vacation.

    If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Des Moines. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

    Frequently Asked Questions

    Can I find a vacation rental in Des Moines?

    Yes, you can find vacation rentals in Des Moines close to Des Moines Civic Center, or you can choose a secluded option if you're looking for extra privacy while you relax. Travelers who like culture and the arts give Des Moines high marks for its lively festivals and acclaimed theater scene. Leave some time to check out the great live music and top-notch restaurants during your visit.

    What are some of the best vacation home rentals that Des Moines has to offer?

    SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!: Visitors give good reviews to this Des Moines vacation home rental, which offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. Some other top choices in Des Moines are "The Hay Loft" - Hot Tub - Game Room - Fire Pit - Office - Family FUN and Beautiful home minutes from downtown! .

    How many vacation rentals are there in Des Moines?

    With 254 Expedia vacation rentals, you're sure to find just the right place for your Des Moines stay.

    What’s there to see and do in Des Moines?

    Enjoy the outdoors at Greater Des Moines Botanical Garden and John and Mary Pappajohn Sculpture Park, or simply take in cultural attractions like World Food Prize Hall of Laureates and Wooly's. Des Moines Civic Center and Des Moines' Downtown Farmers' Market are other places to visit while you're in town.

    What’s a vacation rental in Des Moines like?

    A vacation rental is a private property where you can stay for a few weeks or just a few days in Des Moines. Vacation rentals offer extras such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for small groups.

    Explore a world of travel with Expedia