Plan your trip
Check prices for these dates, December 15 – 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Des Moines vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.
There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Des Moines vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.
Whenever you want to travel, a warm welcome awaits you in Des Moines. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Des Moines in high season.
Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $114 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!
At Expedia, we put the best Des Moines vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.
To find some top Des Moines rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Des Moines vacation.
If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Des Moines. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.
Yes, you can find vacation rentals in Des Moines close to Des Moines Civic Center, or you can choose a secluded option if you're looking for extra privacy while you relax. Travelers who like culture and the arts give Des Moines high marks for its lively festivals and acclaimed theater scene. Leave some time to check out the great live music and top-notch restaurants during your visit.
SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!: Visitors give good reviews to this Des Moines vacation home rental, which offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. Some other top choices in Des Moines are "The Hay Loft" - Hot Tub - Game Room - Fire Pit - Office - Family FUN and Beautiful home minutes from downtown! .
With 254 Expedia vacation rentals, you're sure to find just the right place for your Des Moines stay.
Enjoy the outdoors at Greater Des Moines Botanical Garden and John and Mary Pappajohn Sculpture Park, or simply take in cultural attractions like World Food Prize Hall of Laureates and Wooly's. Des Moines Civic Center and Des Moines' Downtown Farmers' Market are other places to visit while you're in town.
A vacation rental is a private property where you can stay for a few weeks or just a few days in Des Moines. Vacation rentals offer extras such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for small groups.