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Find 5 Star Hotels in Des Moines, IA from $76

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    Check prices for these dates, December 12 – 13, 2026

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    Top Des Moines Hotel Reviews

    Hotel Fort Des Moines, Curio Collection by Hilton

    A spacious lobby with high ceilings, large windows, and a chandelier.

    Des Lux Hotel

    A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

    Home2 Suites by Hilton Des Moines at Drake University

    An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

    Surety Hotel, Autograph Collection

    A modern bar with wooden shelves and a long counter.

    Homewood Suites by Hilton Des Moines Airport

    A modern hotel lobby with a round coffee table, sofas, and a TV mounted on the wall.

    Baymont by Wyndham Des Moines Airport

    A sunroom with a glass ceiling, wicker furniture, and potted plants.

    Tru By Hilton Norwalk Des Moines

    Exterior

    Drury Inn & Suites West Des Moines

    An indoor swimming pool with a 30 ft depth sign, a reception area, and a 'No Lifeguard' warning sign.

    Hyatt Place Altoona/Des Moines

    An outdoor seating area with sofas and tables, stone pillars, and a pathway leading to a building.

    Tru By Hilton Grimes Des Moines

    A modern lounge area with a grey sofa, red chairs, and round tables.

    Fairfield Inn & Suites Des Moines Altoona

    A hotel with a reflection in a calm body of water, surrounded by open fields.

    Staybridge Suites Des Moines Downtown by IHG

    A modern building with a sign that reads 'Staybridge Suites.' It features a mix of glass and brick facades, large windows, and a flat roof.

    Holiday Inn Express & Suites Des Moines Downtown by IHG

    An indoor swimming pool with clear water, a no diving sign, and a pool ladder.

    Hotel Renovo Des Moines Urbandale,Tapestry Collection Hilton

    A spacious bar area with high ceilings, large windows, and multiple bar stools.

    Hyatt Place West Des Moines Jordan Creek

    A modern hotel with a glass facade, a covered entrance, and a landscaped area.

    Find out more about Des Moines

    Ready to experience the next standard in luxury? We know you're thinking about it. Treat your every desire on your upcoming sabbatical. There's no reason to delay a getaway to Des Moines any longer. You'll join the multitudes of vacationers who have made Des Moines so fashionable in the last year. The accommodations in Des Moines also offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. What are you waiting for? Reserve one of our 5-star hotels in Des Moines and indulge in the finer things in life for a while.

    Book the Best Des Moines 5-Star Hotels

    You can expect high quality from your hotel. Top-notch customer care, spacious rooms, and deeply relaxing spa offerings are waiting for you. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. You'll be pleased to note that the hotels in Des Moines offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. What creature comforts do you want in your lodging? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A reflexology treatment that will leave you feeling like a million bucks? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Then explore the 784 reviews various guests have left on Expedia and get to know these places.

    Can't wait to get outside? You're in luck. You'll find heaps to do in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals -- they'll be happy to sit down for a pint or a cuppa.

    Your Getaway Starts Today

    The results are in, and Des Moines 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Select one of Expedia's Des Moines 5-star hotels today and relax in luxe surroundings when you're ready.

    Frequently Asked Questions

    How much does it cost to stay in a 5-star hotel in Des Moines?

    How much you pay for a 5-star hotel in Des Moines depends on things such as when you want to go and the length of your vacation. An insider tip for bagging the best deal? Use our pricing filters to check out the available hotels for your preferred dates.

    What makes a hotel 5 stars in Des Moines?

    In Des Moines, a hotel is required to offer a specific amount of upscale amenities to be rated 5 stars. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused service. You can look forward to things like nightly turn-down services, in-room massages and concierge services. Some may also offer special touches such as a welcome gift.

    Are there any 5-star all-inclusive resorts in Des Moines?

    Expedia's filter tool is the easiest way to narrow down what you want. Select "5-star" and "All inclusive" to show the finest hotels in Des Moines where your room, meals, activities and entertainment are included in the upfront price. At these stays, your trip is absolute indulgence from the moment you arrive.

    Are there any 5-star vacation rentals in Des Moines?

    Our site doesn't offer any 5-star vacation rentals in Des Moines. However, you will still find some top-rated options where the only thing on your itinerary will be to unpack and enjoy yourself. Discover what's available by checking out our vacation rentals in Des Moines.

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