Are there any 5-star vacation rentals in Des Moines?

Our site doesn't offer any 5-star vacation rentals in Des Moines. However, you will still find some top-rated options where the only thing on your itinerary will be to unpack and enjoy yourself. Discover what's available by checking out our vacation rentals in Des Moines .

Des Moines showing a bridge, a skyscraper and a sunset

Find 5 Star Hotels in Des Moines, IA from $143

Upfront pricing

Our total price for your stay includes taxes and fees

Treat yourself

Save 10% or more on over 100,000 hotels worldwide with Member Prices

Learn about One Key

Be picky

Search almost a million properties worldwide

Check availability on Des Moines 5 Star Hotels

Tonight

Tomorrow

This weekend

Next weekend

Compare Des Moines 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Des Moines.

Hotel Fort Des Moines, Curio Collection by Hilton

1000 Walnut St, Des Moines, IA

$138 nightly

$154 total

Jul 21 - Jul 22

Total includes taxes and fees

9.4/10 Exceptional! (1,008 reviews)

Still don't see what you're looking for?

See all properties in Des Moines.

You can also use these popular filters to refine your search.

Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines and related destinations

Wander through the striking Pappajohn Sculpture Park before catching a Broadway show at the historic Des Moines Civic Center. The weekend Downtown Farmers' Market transforms Court Avenue with local foods, while the gold-domed State Capitol offers free tours with spectacular city views.

See all hotels in Des Moines

Find out more about Des Moines

Ready to experience the next standard in luxury? We know you're thinking about it. Treat your every desire on your upcoming sabbatical. There's no reason to delay a getaway to Des Moines any longer. You'll join the multitudes of vacationers who have made Des Moines so fashionable in the last year. The accommodations in Des Moines also offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. What are you waiting for? Reserve one of our 5-star hotels in Des Moines and indulge in the finer things in life for a while.

Book the Best Des Moines 5-Star Hotels

You can expect high quality from your hotel. Top-notch customer care, spacious rooms, and deeply relaxing spa offerings are waiting for you. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. You'll be pleased to note that the hotels in Des Moines offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. What creature comforts do you want in your lodging? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A reflexology treatment that will leave you feeling like a million bucks? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Then explore the 784 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? You're in luck. You'll find heaps to do in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals -- they'll be happy to sit down for a pint or a cuppa.

Your Getaway Starts Today

The results are in, and Des Moines 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Select one of Expedia's Des Moines 5-star hotels today and relax in luxe surroundings when you're ready.

Explore a world of travel with Expedia

Flights to Iowa

Things to do in Iowa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Des Moines?

How much you pay for a 5-star hotel in Des Moines depends on things such as when you want to go and the length of your vacation. An insider tip for bagging the best deal? Use our pricing filters to check out the available hotels for your preferred dates.

Search for the lowest price per night from $143

What makes a hotel 5 stars in Des Moines?

In Des Moines, a hotel is required to offer a specific amount of upscale amenities to be rated 5 stars. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused service. You can look forward to things like nightly turn-down services, in-room massages and concierge services. Some may also offer special touches such as a welcome gift.

Are there any 5-star all-inclusive resorts in Des Moines?

Expedia's filter tool is the easiest way to narrow down what you want. Select "5-star" and "All inclusive" to show the finest hotels in Des Moines where your room, meals, activities and entertainment are included in the upfront price. At these stays, your trip is absolute indulgence from the moment you arrive.

Unlock instant savings with Member Prices