Title: Top Independent in O Brien, FL  - Expedia.com

[O Brien Travel Guide](https://expedia.com/O-Brien.dx3000431472)[Hotels in O Brien](https://expedia.com/O-Brien-Hotels.d3000431472.Travel-Guide-Hotels)[Vacation Rentals in O Brien](https://expedia.com/O-Brien-Vacation-Rentals.d3000431472.Travel-Guide-VacationRentals)[Flights to O Brien](https://expedia.com/Cheap-Flights-To-O-Brien.d3000431472.Travel-Guide-Flights)[Car Rentals in O Brien](https://expedia.com/Car-Rentals-In-O-Brien.d3000431472.Car-Rental-Guide)[O Brien Vacation Packages](https://expedia.com/O-Brien.d3000431472.Destination-Travel-Guides)

![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

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[Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-23&endDate=2026-03-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Top O Brien Hotel Reviews

![Tru by Hilton Lake City](https://images.trvl-media.com/lodging/35000000/34870000/34865600/34865542/539e711a_y.jpg)

### Tru by Hilton Lake City

10/10 Excellent

"Clean, plenty of well lit parking, friendly staff. Breakfast was good and hot.Id stay here again"

[](https://expedia.com/Lake-City-Hotels-Tru-By-Hilton-Lake-City.h34865542.Hotel-Information)

![Baymont by Wyndham Lake City I-75](https://images.trvl-media.com/lodging/1000000/20000/15800/15747/84b0e094_y.jpg)

### Baymont by Wyndham Lake City I-75

6/10 Okay

"Shower handle about to fall off"

[](https://expedia.com/Lake-City-Hotels-Baymont-By-Wyndham-Lake-City.h15747.Hotel-Information)

![Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/5b1d647e_y.jpg)

### Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Fue una experiencia muy agradable. "

[](https://expedia.com/Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information)

![Americas Best Value Inn Lake City](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/fddc9a15_y.jpg)

### Americas Best Value Inn Lake City

6/10 Okay

"Room was small, breakfast was a joke, they was working on the room above us till midnight "

[](https://expedia.com/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information)

![Comfort Suites Lake City](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/2b2698df_y.jpg)

### Comfort Suites Lake City

10/10 Excellent

"Family of 4\. Stay was very pleasant and clean. Great costumer service! Would 100% stay here again!"

[](https://expedia.com/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information)

![La Quinta Inn & Suite by Wyndham Lake City](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571_y.jpg)

### La Quinta Inn & Suite by Wyndham Lake City

6/10 Okay

"We really hate the fan noice in the bathroom. It never stops!! Toilet seat was falling off. You would think the maids would notice. No hand soap left just an empty wrapper. We probably wouldn’t stay there again. "

[](https://expedia.com/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information)

![BlueGem Motel](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/dffd0064_y.jpg)

### BlueGem Motel

10/10 Excellent

"Wonderful staff nice location clean rooms"

[](https://expedia.com/High-Springs-Hotels-BlueGem-Motel.h87671816.Hotel-Information)

![Best Western Plus Lake City](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca_y.jpg)

### Best Western Plus Lake City

8/10 Good

"I would say that shower is a little out dated "

[](https://expedia.com/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information)

![Holiday Inn Express & Suites Alachua - Gainesville Area by IHG](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/e851cfaf_y.jpg)

### Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

8/10 Good

"Updated property with amenities ingood location"

[](https://expedia.com/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information)

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