Title: Top Independent in O Brien, FL - Expedia.com [O Brien Travel Guide](https://expedia.com/O-Brien.dx3000431472)[Hotels in O Brien](https://expedia.com/O-Brien-Hotels.d3000431472.Travel-Guide-Hotels)[Vacation Rentals in O Brien](https://expedia.com/O-Brien-Vacation-Rentals.d3000431472.Travel-Guide-VacationRentals)[Flights to O Brien](https://expedia.com/Cheap-Flights-To-O-Brien.d3000431472.Travel-Guide-Flights)[Car Rentals in O Brien](https://expedia.com/Car-Rentals-In-O-Brien.d3000431472.Car-Rental-Guide)[O Brien Vacation Packages](https://expedia.com/O-Brien.d3000431472.Destination-Travel-Guides) ![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 2 - Mar 3](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 3 - Mar 4](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-03&endDate=2026-03-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=3000431472&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FO-Brien-Hotels-Independent.0-0-d3000431472--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FO-Brien-Hotels-Independent.0-0-d3000431472--bIndependent.Travel-Guide-Filter-Hotels) ## Top O Brien Hotel Reviews ![La Quinta Inn & Suite by Wyndham Lake City](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571_y.jpg) ### La Quinta Inn & Suite by Wyndham Lake City 10/10 Excellent "The room was clean and the front desk staff was wonderful!!!" [](https://expedia.com/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) ![Americas Best Value Inn Lake City](https://images.trvl-media.com/lodging/2000000/1040000/1039800/1039754/1bfc5692_y.jpg) ### Americas Best Value Inn Lake City 10/10 Excellent "The room was clean , but the carpet is well worn. The washroom was clean and the towels fresh. Staff at the front desk were very friendly and welcoming. " [](https://expedia.com/Lake-City-Hotels-Americas-Best-Value-Inn-Lake-City.h1039754.Hotel-Information) ![Quality Inn Lake City](https://images.trvl-media.com/lodging/1000000/490000/484100/484004/cbec2bb3_y.jpg) ### Quality Inn Lake City 10/10 Excellent "Great staff breakfast and room" [](https://expedia.com/Lake-City-Hotels-Quality-Inn-Lake-City.h484004.Hotel-Information) ![Fairfield Inn & Suites Lake City](https://images.trvl-media.com/lodging/3000000/2080000/2076600/2076513/9a0ddc50_y.jpg) ### Fairfield Inn & Suites Lake City 10/10 Excellent "Clean room, friendly staff, most comfortable beds ever and great breakfast!!!" [](https://expedia.com/Lake-City-Hotels-Fairfield-Inn-Suites-Lake-City.h2076513.Hotel-Information) ![Comfort Suites Lake City](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/7f945643_y.jpg) ### Comfort Suites Lake City 10/10 Excellent "Spacious room, helpful staff, clean,lots of places to store things. Fitness center dated but clean" [](https://expedia.com/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) ![Days Inn by Wyndham Lake City I-75](https://images.trvl-media.com/lodging/1000000/20000/17700/17650/eb9ba6b8_y.jpg) ### Days Inn by Wyndham Lake City I-75 10/10 Excellent "Staff where amazing " [](https://expedia.com/Lake-City-Hotels-Days-Inn-By-Wyndham-Lake-City-I-75.h17650.Hotel-Information) ![Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/fce767a1_y.jpg) ### Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "Cabins by Gilchrist is the kind of place that reminds you why getaways are so important. Everything about our stay was amazing. From the cozy, beautifully kept cabin to the peaceful, scenic surroundings that instantly make you feel relaxed and recharged. The cabin was spotless, comfortable, and thoughtfully set up, and the whole experience felt effortless and special. One of the best parts was sitting outside at night, starting a fire, and just watching the stars. There’s something unreal about how quiet and calm it is. Yyou can truly unplug and enjoy the moment. Whether you’re looking for a romantic escape, a quiet reset, or just time to disconnect and breathe, this place delivers in every way. This wasn’t just a stay, it was an experience. Staff was very attentive with daily communication. I had to text them once and they responded immediately while still respecting the privacy. I genuinely can’t recommend Cabins by Gilchrist enough and will absolutely be back. If you’re thinking about booking, do it. You won’t regret it." [](https://expedia.com/Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) ![Courtyard By Marriott Lake City](https://images.trvl-media.com/lodging/100000000/99930000/99922700/99922616/9c441019_y.jpg) ### Courtyard By Marriott Lake City 10/10 Excellent "Yes " [](https://expedia.com/Lake-City-Hotels-Courtyard-By-Marriott-Lake-City.h99922616.Hotel-Information) ![Best Western Plus Lake City](https://images.trvl-media.com/lodging/1000000/910000/901400/901396/a415bbca_y.jpg) ### Best Western Plus Lake City 10/10 Excellent "The room was spotless and beautiful! Kcup coffee maker, nice size fridge & microwave. Beautiful room and large TV. Everything looked brand new! " [](https://expedia.com/Lake-City-Hotels-Best-Western-Plus-Lake-City.h901396.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Troy Spring State Park ](https://www.expedia.com/Troy-Spring-State-Park-Hotels.0-l6285999-0.Travel-Guide-Filter-Hotels) - [Branford Hotels ](https://www.expedia.com/Branford-Hotels.d6188028.Travel-Guide-Hotels) - [Motels in Branford ](https://www.expedia.com/Branford-Motels.d6188028-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Branford ](https://www.expedia.com/Branford-Cabins.d6188028-aaCabins.Travel-Guide-Accommodation) - [Rv Parks in Branford ](https://www.expedia.com/Branford-RV-Parks.d6188028-aaRVParks.Travel-Guide-Accommodation) - [Apartments in Branford ](https://www.expedia.com/Branford-Apartments.d6188028-aaApartments.Travel-Guide-Accommodation) - [4 Star Hotels in Branford ](https://www.expedia.com/4Star-Branford-Hotels.s40-0-d6188028.Travel-Guide-Filter-Hotels) - 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