Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Start by selecting your hotel
Start by selecting your hotel
Start by selecting your hotel

Save up to $603 by booking Flight + Hotel.

Search 590,000 properties and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more


Panama City Vacation Travel Guide

Accommodation in Panama City

Pre-booking the perfect place to stay often equates to care-free vacations. You'll find some of the finest lodging deals in Panama City on Expedia's comprehensive Panama City lodging guide.

Visitors seeking accommodations at the upper-end of the scale won't be disappointed, Panama City features a range of upmarket places, including the American Trade Hotel, at Plaza Herrera Casco Viejo, and the Las Clementinas, at Casco Antiguo, Calle 11 Y Ave B. Alternatively, if you're on a tight budget, you'll be sure to find a bargain at the InterContinental Miramar Panama, at Miramar Plaza, Balboa Avenue, or The Westin Playa Bonita Panama, at Km 6 Road to Veracruz.

It’s easy to book the getaway of your dreams when you search through our selection of Panama City vacations. Our goal? To create the perfect trip for you by providing the largest selection of vacation packages. Confidently book your getaway thanks to our trustworthy recommendations and verified consumer reviews from travelers just like you. Personalize your Panama City package with our myriad of hotel rooms and flight tickets, which help to create a vacation specifically for you. Simply sort through our selection and pick and choose the elements that best suit your preferences and price range.

Because we offer the best rates, you can book your travel reservations knowing you won’t find lower prices elsewhere. These discounts are so great, you’ll feel like you gained the title of the ultimate bargain hunter with our Panama City vacation package deals. Whether you’re looking to book multiple flights, stay at the fanciest hotel, or explore the hottest local attractions, you’ll find discounted travel arrangements within your budget right here. You shouldn’t have a care in the world when you go on vacation, so our discounts allow you to rest easy without giving your bank account a second thought. Save money on your vacation today and revel in your much-deserved getaway tomorrow.


Top Hotel Deals

See all 163 Hotels in Panama City
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.5 out of 5.0

Just 1 mile (1.6 km) from the airport, this Panama City hotel is 5 minutes from the shopping center Shopping Metro Mall and 10 minutes from the ruins of Panamá Viejo.

Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City
5.0 out of 5.0

This family-friendly Panama City hotel is located by the ocean, within 1 mi (2 km) of Multicentro Panama and Via Espana. Multiplaza Pacific Mall is 1.8 mi (2.9 km) away.

Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

Ave. Domingo Diaz, Tocumen
4.5 out of 5.0

Situated near the airport, this hotel is within 9 mi (15 km) of Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. Panama Viejo and National Craft Market are also within 12 mi (20 km).

Novotel Panama City

Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City
4.5 out of 5.0

Located in El Cangrejo, this hotel is within a 15-minute walk of Theater Circle, National Shrine of the Heart of Mary, and Via Espana. Colonial Religious Art Museum and Panama Canal Murals are also within 15 minutes.

$159
Trump International Hotel and Tower Panama

Trump International Hotel and Tower Panama

Calle Punta Colon, Punta Pacifica, Panama City
5.0 out of 5.0

This family-friendly Panama City hotel is located on the waterfront, within 1 mi (2 km) of Multicentro Panama and Multiplaza Pacific Mall. Via Espana and National Shrine of the Heart of Mary are also within 2 mi (3 km).

RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
4.5 out of 5.0

Located in the heart of Bella Vista, this spa hotel is 0.3 mi (0.5 km) from National Shrine of the Heart of Mary and 2.8 mi (4.4 km) from Metropolitan Cathedral of Panama. Via Espana and Multicentro Panama are also within 15 minutes.

Hyatt Place Panama City/Downtown

Hyatt Place Panama City/Downtown

Avenida Aquilino de la Guardia, between, Panama City
4.0 out of 5.0

Situated in Bella Vista, this hotel is 0.2 mi (0.3 km) from Via Espana and 2.5 mi (4.1 km) from Metropolitan Cathedral of Panama. National Shrine of the Heart of Mary and Multicentro Panama are also within 1 mi (2 km).

Hilton Panama

Hilton Panama

Balboa Ave. and Aquilino De La Guardia, Panama City
5.0 out of 5.0

Located in the heart of Bella Vista, this luxury hotel is 0.7 mi (1.1 km) from Via Espana and 2.4 mi (3.8 km) from Metropolitan Cathedral of Panama. Multicentro Panama and National Shrine of the Heart of Mary are also within 1 mi (2 km).

Top Flight + Hotel Deals