Panama City Vacations from $738

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Your Panama City Vacation

The tropical climate, cosmopolitan vibe and rich history are three of the many reasons why people love this coastal city. Discover this incredible destination as you please with a Panama City vacation package. Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama are just a few of the sights worth exploring during your trip to Panama City. A few quick clicks is all it takes to put together your dream Panama City vacation on Expedia.

The Latest Panama City vacation packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites
Central Hotel Panama Casco Viejo
Villa Botero By Casa Mojito B&B
Playa Caracol Residences Vacation Rental
Villa Marina Lodge & Condos
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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Discover the most popular places to visit in Panama City

What to do in Panama City

Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $127 total per night from Feb 4 to Feb 5
$127 total
Feb 4 - Feb 5
Total with taxes and fees
9/10 Wonderful! (4,823 reviews)
The bed wasn’t comfortable and the windows were always blurry due to the humidity. Couldn’t see the city like I wanted to.

Reviewed on Jan 12, 2026

Hotel Riu Plaza Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $135 total per night from Jan 25 to Jan 26
$135 total
Jan 25 - Jan 26
Total with taxes and fees
8.8/10 Excellent! (1,024 reviews)
Going location, great city views

Reviewed on Jan 4, 2026

Las Americas Golden Tower Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $243 total per night from Feb 6 to Feb 7
$243 total
Feb 6 - Feb 7
Total with taxes and fees
8.8/10 Excellent! (1,004 reviews)
awesome location, great staff

Reviewed on Jan 12, 2026

Waldorf Astoria Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Panama City Vacation Packages

Things to do in and around Panama City

Panama City offers a vibrant mix of activities perfect for families and business travelers alike. Enjoy shopping at various malls and centers, explore local attractions with a tour guide, or indulge in a round of golf. For a fun-filled day, consider day trips or relaxing beach vacations along Panama City’s stunning coastline. With so much to see and do, you'll find endless entertainment in this dynamic city.

Shopping

For a vibrant shopping experience in Panama City, visit Albrook Shopping Mall for entertainment and diverse shops. Uruguay Street offers local businesses and family-friendly vibes. Don't miss the National Craft Market for unique souvenirs. If you're up for a drive, check out other malls outside the city for more options.

Recreation

Estadio Rommel Fernandez offers an energetic atmosphere perfect for sports enthusiasts, while Estadio Nacional Rod Carew provides thrilling events for fans. For a cultural experience, the National Theater showcases captivating performances, making it an ideal spot for entertainment and family bonding in the heart of Panama City.

Adventure

At Gatun Eco Adventures, located 29 miles from Panama City, experience thrilling ziplining through lush canopies, perfect for adrenaline seekers. Alternatively, hike the Honeycreeper Ridge Trail, 25 miles away, offering stunning scenery and a chance to connect with nature amidst adventure-filled vibes.

Nightlife

In Panama City, experience the vibrant nightlife in areas like Casco Viejo and the financial district. Enjoy lively clubs, rooftop bars, and salsa dancing at venues such as Tantalo and La Factoría, where the atmosphere is electric and the music keeps you dancing until dawn.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Panama City

Panama City offers a vibrant mix of family-friendly, urban experiences perfect for business and leisure travelers. Explore popular attractions like urban parks and event venues, while soaking in the local culture. Don't miss the beautiful beaches nearby, which provide a perfect escape for relaxation and fun. Whether you're interested in sightseeing or enjoying outdoor activities, Panama City has something to keep everyone entertained.

  • Cinta Costera: Experience the vibrant atmosphere of this urban park in Panama City. Perfect for families and outdoor enthusiasts, Cinta Costera features scenic walking paths, playgrounds, and stunning views of the city skyline and the Pacific Ocean, making it an ideal spot for relaxation and recreation.
  • Avenida Balboa: This bustling street is the heart of Panama City, lined with high-rises, restaurants, and shops. Stroll along the waterfront promenade to soak in the lively city vibes, offering a perfect blend of urban energy and picturesque views.
  • Amador Causeway: A cultural gem, Amador Causeway connects several islands and offers breathtaking views of the Panama Canal and city skyline. Explore museums, enjoy local cuisine, and immerse yourself in the rich history and culture of Panama.

Best time to go to Panama City

The best time to visit Panama City can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panama City falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Panama City falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnySlightly HighSlightly High
February79.2°F (26.2°C)No RainMostly SunnyAverageAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowAverage

Tips to save on your trip to Panama City

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Panama City.
  • Consider traveling during the off-peak season (typically September to November) for more affordable package holidays to Panama City.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Panama City Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Veracruz Beach, Metropolitan Cathedral of Panama and Soberania National Park

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Frequently asked questions

How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination from $738 on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
January, July and December are great times to look for cheap Panama City vacation packages. Traveling in less busy periods means you can typically find lower prices on hotels and flights.
How many days is enough for Panama City?
Panama City vacations can be as short or long as you like, but to get a real feel for this destination, we reckon 3 days is about right. In this timeframe, you can visit headline attractions like Frank Gehry Biodiversity Museum and Museum of History Panama as well as underrated gems. Don't skip neighborhoods such as Campo Alegre and El Cangrejo either. If you're clever with your time, you can even take a day trip from Panama City too.
Is it worth booking a vacation package to Panama City?
Panama City has everything you need for an amazing break — culture, nature and nightlife are just the start. Whether you want to visit attractions like Metropolitan Cathedral of Panama and Albrook Shopping Mall, or venture off the beaten track, you'll have plenty to experience on your Panama City vacation.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?

  1. Pick your travel dates: What you want to do in Panama City and your favorite season can help you decide when to get away.
  2. Figure out your budget: Ensure you have enough money to cover everything from meals and transportation to activities and flights. Your accommodations will probably be the biggest expense during your trip to Panama City.
  3. Organize your Panama City getaway with Expedia's trip planning tool: Search for and book hotels and experiences all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Panama City together.
  4. Decide how long to go away for: Now that you're more familiar with Panama City, you can figure out the perfect length of your break. Put together a draft plan and allocate enough time to cover everything you want to see.
  5. Bundle your hotel and flights: Awesome destination, check. Length of stay, check. All that's left is to pick a Panama City vacation package that brings all your bookings together.
  6. Book any activities or day trips: Here's the fun part — organizing everything you want to do and see. Check out some of the incredible things to do in Panama City and reserve your tickets in advance to save time (and maybe some spending money too!).

Does Expedia offer Book Now, Pay Later Panama City vacation packages?
Set off on your dream trip to Panama City with Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or hold off until the next payday — we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily budget for your trip and snap up travel deals before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.