Panama City Vacations from $694

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Your Panama City Vacation

The tropical climate, cosmopolitan vibe and rich history are three of the many reasons why people love this coastal city. Discover this incredible destination as you please with a Panama City vacation package. Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama are just a few of the sights worth exploring during your trip to Panama City. A few quick clicks is all it takes to put together your dream Panama City vacation on Expedia.

The Latest Panama City vacation packages

Price found within the past 48 hours. Click for updated prices.
Nomada Republic Hotel Punta Chame

Nomada Republic Hotel Punta Chame

3 out of 5
per person
Aug 30 - Sep 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (25 reviews)
Unique stay for sure. We stayed in one of the smaller “containers”. It was fine for us, others might find it tight. The larger units looked like they had some dining area and a bit more space. A few extra hooks on the wall or in the very tiny bathroom would be nice for towels. The first floor units are great for pool side, second floor units have a porch but you have to go around the building to access your door. A few extra chairs on the first floor entry decks would be nice as we had to share. Fantastic restaurant on site, not a huge menu but we had 4 great meals. No breakfast menu but we heard from another guest it was available? The manager (Carlos) lives on site and was amazing. You do not need to kite surf to appreciate the skill and we spent hours watching the show with a front row seat. New stairs for access to the beach were being build while we were there. Be prepared for an abundance of plastic refuse brought in by the tide that lines the beach. Definitely recommend a stay here.

Reviewed on Mar 1, 2024

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
Sep 30 - Oct 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (925 reviews)
Love the location and the restaurant inside the hotel was phenomenal.

Reviewed on Jul 11, 2025

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Sep 28 - Oct 3
found 12 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Oct 2 - Oct 7
found 7 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
No reviews
Casa Fofo Family House

Casa Fofo Family House

3 out of 5
per person
Sep 28 - Oct 3
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
No reviews
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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
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Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Discover the most popular places to visit in Panama City

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4.5/5(456 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa

What to do in Panama City

Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

$149
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

$32
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panama: Visit an Indian village Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

$47
per adult
94% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
See all activities in Panama City

Panama City Hotel Deals

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (4,095 reviews)
"I really love it there it reminds me of home"

Reviewed on Jul 12, 2025

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Hotel Riu Plaza Panama
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
8.4/10 Very Good! (891 reviews)
"a clean and nice hotel , Lobby area was very nice with some nice shopping places, the rooms need a little update especially the bathroom, the service was excellent friendly and courteous"

Reviewed on Jul 8, 2025

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Sheraton Grand Panama
Waymore Hotel Spa & Casino
Waymore Hotel Spa & Casino
4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (332 reviews)
"This is a very clean and fancy hotel. The location is not ideal, but the amenities make it worth it."

Reviewed on Jul 10, 2025

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Waymore Hotel Spa & Casino
See all 1,405 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Panama City Vacation Packages

Panama City Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Veracruz Beach, Metropolitan Cathedral of Panama and Soberania National Park

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Frequently asked questions

How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination from $694 on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
January, July and December are great times to look for cheap Panama City vacation packages. Traveling in less busy periods means you can typically find lower prices on hotels and flights.
How many days is enough for Panama City?
Panama City vacations can be as short or long as you like, but to get a real feel for this destination, we reckon 3 days is about right. In this timeframe, you can visit headline attractions like Frank Gehry Biodiversity Museum and Museum of History Panama as well as underrated gems. Don't skip neighborhoods such as Campo Alegre and El Cangrejo either. If you're clever with your time, you can even take a day trip from Panama City too.
Is it worth booking a vacation package to Panama City?
Panama City has everything you need for an amazing break --- culture, nature and nightlife are just the start. Whether you want to visit attractions like Metropolitan Cathedral of Panama and Albrook Shopping Mall, or venture off the beaten track, you'll have plenty to experience on your Panama City vacation.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?

  1. Pick your travel dates: What you want to do in Panama City and your favorite season can help you decide when to get away.
  2. Figure out your budget: Ensure you have enough money to cover everything from meals and transportation to activities and flights. Your accommodations will probably be the biggest expense during your trip to Panama City.
  3. Organize your Panama City getaway with Expedia's trip planning tool: Search for and book hotels and experiences all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Panama City together.
  4. Decide how long to go away for: Now that you're more familiar with Panama City, you can figure out the perfect length of your break. Put together a draft plan and allocate enough time to cover everything you want to see.
  5. Bundle your hotel and flights: Awesome destination, check. Length of stay, check. All that's left is to pick a Panama City vacation package that brings all your bookings together.
  6. Book any activities or day trips: Here's the fun part --- organizing everything you want to do and see. Check out some of the incredible things to do in Panama City and reserve your tickets in advance to save time (and maybe some spending money too!).

Does Expedia offer Book Now, Pay Later Panama City vacation packages?
Set off on your dream trip to Panama City with Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or hold off until the next payday --- we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily budget for your trip and snap up travel deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.