Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Start by selecting your hotel
Start by selecting your hotel
Start by selecting your hotel

Save up to $603 by booking Flight + Hotel.

Search 590,000 properties and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more


Panama City Vacation Travel Guide

Accommodation in Panama City

Pre-booking the perfect place to stay often equates to care-free vacations. You'll find some of the finest lodging deals in Panama City on Expedia's comprehensive Panama City lodging guide.

Visitors seeking accommodations at the upper-end of the scale won't be disappointed, Panama City features a range of upmarket places, including the American Trade Hotel, at Plaza Herrera Casco Viejo, and the Las Clementinas, at Casco Antiguo, Calle 11 Y Ave B. Alternatively, if you're on a tight budget, you'll be sure to find a bargain at the InterContinental Miramar Panama, at Miramar Plaza, Balboa Avenue, or The Westin Playa Bonita Panama, at Km 6 Road to Veracruz.

It’s easy to book the getaway of your dreams when you search through our selection of Panama City vacations. Our goal? To create the perfect trip for you by providing the largest selection of vacation packages. Confidently book your getaway thanks to our trustworthy recommendations and verified consumer reviews from travelers just like you. Personalize your Panama City package with our myriad of hotel rooms and flight tickets, which help to create a vacation specifically for you. Simply sort through our selection and pick and choose the elements that best suit your preferences and price range.

Because we offer the best rates, you can book your travel reservations knowing you won’t find lower prices elsewhere. These discounts are so great, you’ll feel like you gained the title of the ultimate bargain hunter with our Panama City vacation package deals. Whether you’re looking to book multiple flights, stay at the fanciest hotel, or explore the hottest local attractions, you’ll find discounted travel arrangements within your budget right here. You shouldn’t have a care in the world when you go on vacation, so our discounts allow you to rest easy without giving your bank account a second thought. Save money on your vacation today and revel in your much-deserved getaway tomorrow.


Top Hotel Deals

See all 173 Hotels in Panama City
RIU Plaza Panama $93
RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
     
    4.4
    of 5, from 1,578 reviews
    4.0 out of 5.0

    Located in the heart of Bella Vista, this spa hotel is within 3 mi (5 km) of Museum of Natural Science, Metropolitan Cathedral of Panama, and Museum of History Panama. Panama Viejo and National Theater are also within 6 mi (10 km).

    Riande Aeropuerto Hotel & Casino $91
    Riande Aeropuerto Hotel & Casino

    Riande Aeropuerto Hotel & Casino

    Vía Tocumen, Tocumen
       
      4.0
      of 5, from 1,925 reviews
      4.0 out of 5.0

      Just 1 mile (1.6 km) from the airport, this Panama City hotel is 5 minutes from the shopping center Shopping Metro Mall and 10 minutes from the ruins of Panamá Viejo.

      Crowne Plaza Panama Airport $90
      Crowne Plaza Panama Airport

      Crowne Plaza Panama Airport

      Ave. Domingo Diaz, Tocumen
         
        4.2
        of 5, from 654 reviews
        4.0 out of 5.0

        Situated near the airport, this hotel is within 9 mi (15 km) of Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. Panama Viejo and National Craft Market are also within 12 mi (20 km).

        DoubleTree by Hilton Hotel Panama City $58
        DoubleTree by Hilton Hotel Panama City

        DoubleTree by Hilton Hotel Panama City

        Via Espana, Federico Boyd & Bella Vista, Panama City
           
          4.1
          of 5, from 1,514 reviews
          4.0 out of 5.0

          Located amid the bustling shops and street vendors of Via España, the DoubleTree by Hilton Hotel Panama City is steps from El Carmen Church and a 25-minute drive from the airport. Multicentro Panama mall is about 1 mile (1.6 km) away, and the historic plazas of the Old City are a 10-minute drive.

          The Bahia Grand Hotel $139
          The Bahia Grand Hotel

          The Bahia Grand Hotel

          Punta Colon Street, Panama City
             
            3.8
            of 5, from 10 reviews
            5.0 out of 5.0

            Situated in the city center, this luxury hotel is close to Multiplaza Pacific Mall, Cinta Costera, and National Theater. Local attractions also include Metropolitan Cathedral of Panama and Plaza de Francia.

            Country Inn & Suites by Radisson, Panama Canal, Panama $75
            Country Inn & Suites by Radisson, Panama Canal, Panama

            Country Inn & Suites by Radisson, Panama Canal, Panama

            Amador Ave & Pelicano Ave, Panama City
               
              4.1
              of 5, from 1,166 reviews
              3.5 out of 5.0

              At the entrance of the Panama Canal, close to Smithsonian’s Tropical Research Institute, Bridge of the Americas, and Panama Old Quarters. This business-friendly hotel is located near City of Knowledge, Panama Pacifico Business Park, shipping companies, and the banking center.

              TRYP by Wyndham Panamá Centro $52
              TRYP by Wyndham Panamá Centro

              TRYP by Wyndham Panamá Centro

              Via Veneto, El Cangrejo Bellavista, Panama City
                 
                4.4
                of 5, from 1,240 reviews
                3.5 out of 5.0

                Located in El Cangrejo, this hotel is 0.5 mi (0.8 km) from Via Espana and 2.8 mi (4.6 km) from Metropolitan Cathedral of Panama. National Shrine of the Heart of Mary and Theater Circle are also within 1 mi (2 km).

                Hard Rock Hotel Panama Megapolis $140
                Hard Rock Hotel Panama Megapolis

                Hard Rock Hotel Panama Megapolis

                Ave. Balboa al lado de Multicentro, Panama City
                   
                  4.3
                  of 5, from 2,326 reviews
                  4.5 out of 5.0

                  This family-friendly Panama City hotel is located by the ocean, within 1 mi (2 km) of Multicentro Panama and Via Espana. Multiplaza Pacific Mall is 1.8 mi (2.9 km) away.