Title: Visit Patuxent River: 2026 Travel Guide for Patuxent River, Maryland | Expedia.com [Hotels in Patuxent River](https://expedia.com/Patuxent-River-Hotels.d3000347957.Travel-Guide-Hotels)[Vacation Rentals in Patuxent River](https://expedia.com/Patuxent-River-Vacation-Rentals.d3000347957.Travel-Guide-VacationRentals)[Car Rentals in Patuxent River](https://expedia.com/Car-Rentals-In-Patuxent-River.d3000347957.Car-Rental-Guide)[Patuxent River Vacation Packages](https://expedia.com/Patuxent-River.d3000347957.Destination-Travel-Guides) # Patuxent River, MD ## Travel Guide ## Visit Patuxent River ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_3000347957) - Patuxent River Hotel Deals - Vacation Rentals in Patuxent River ![Comfort Inn & Suites Lexington Park near Pax River](https://images.trvl-media.com/lodging/6000000/5100000/5098400/5098394/11804ad4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn & Suites Lexington Park near Pax River 21885 Three Notch Rd Lexington Park MD $98 nightly $109 total Apr 6 - Apr 7 Total with taxes and fees Book a stay at this business-friendly hotel in Lexington Park. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ... 8.6/10 Excellent! (675 reviews) There was a terrible cigarette smell. We ended having to leave in middle of night because we could no longer stand it. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F6%2F2026&endDate=4%2F7%2F2026&selected=5098394&PinnedHotelID=5098394&HadPinnedHotel=true®ionId=3000347957) ![avid hotel California - Lexington Park by IHG](https://images.trvl-media.com/lodging/119000000/118640000/118639700/118639639/08bcaeff_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### avid hotel California - Lexington Park by IHG 23274 Three Notch Road California MD $101 nightly $112 total Apr 1 - Apr 2 Total with taxes and fees Book a stay at this business-friendly hotel in California. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Wildewood Shopping Center ... 9/10 Wonderful! (29 reviews) Great staff, good parking, good location. Good variety of restaurants to eat. Reviewed on Mar 9, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=118639639&PinnedHotelID=118639639&HadPinnedHotel=true®ionId=3000347957) ![Hilton Garden Inn Solomons](https://images.trvl-media.com/lodging/2000000/1650000/1644700/1644617/0b056987_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn Solomons 13100 Dowell Road Solomons MD $122 nightly $136 total Mar 20 - Mar 21 Total with taxes and fees Book a stay at this business-friendly hotel in Solomons. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ... 8.6/10 Excellent! (646 reviews) Very clean. Nice staff. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&selected=1644617&PinnedHotelID=1644617&HadPinnedHotel=true®ionId=3000347957) [See all 370 properties in Patuxent River](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=3000347957) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Mid-Century Modern Lake House – Gorgeous Fall Views, Fire pit, Sauna, 4BR](https://images.trvl-media.com/lodging/117000000/116480000/116479600/116479519/17aef2af_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Mid-Century Modern Lake House – Gorgeous Fall Views, Fire pit, Sauna, 4BR Lusby MD Stay at this vacation home in Lusby. Enjoy free WiFi, a fitness center, and a garden. Popular attractions Chesapeake Hills Golf Course and Annmarie Sculpture ... 9.6/10 Exceptional! (7 reviews) Nice house in a great location. Great for groups. Reviewed on Dec 9, 2025 [](https://expedia.com/Lusby-Hotels-Midcentury-Modern-Lake-House.h116479519.Hotel-Information) ![Family and Pet-Friendly, Waterfront with Pier](https://images.trvl-media.com/lodging/34000000/33510000/33506200/33506110/1dc9ddc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Family and Pet-Friendly, Waterfront with Pier Cambridge MD Stay at this cottage in Cambridge. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ragged Island and Spocott Windmill are located ... 10/10 Exceptional! (265 reviews) The property is lovely, and so are the hosts. We were all very happy with our stay. Cambridge is an interesting place, and the views from our unit were spectacular. So much to do just being on the property. We all enjoyed our long weekend. Reviewed on Dec 3, 2025 [](https://expedia.com/Cambridge-Hotels-Family-And-Pet-Friendly.h33506110.Hotel-Information) ![Waterfront Wildlife Retreat on the Patuxent River ](https://images.trvl-media.com/lodging/31000000/30100000/30094800/30094730/2e7fb2c4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Waterfront Wildlife Retreat on the Patuxent River Lusby MD Stay at this vacation home in Lusby. Enjoy free WiFi, laundry facilities, and patios. Our guests praise the helpful staff in our reviews. Popular attractions ... 10/10 Exceptional! (176 reviews) The host was very welcoming and helpful. Home was comfortable and quiet. Homeowner very responsive to our questions and needs. It was a peaceful retreat Reviewed on Mar 1, 2026 [](https://expedia.com/Lusby-Hotels-Waterfront-Wildlife-Retreat-On-The-Patuxent-River.h30094730.Hotel-Information) [See all properties in Patuxent River](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000347957&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Patuxent River hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=2026-03-10&endDate=2026-03-11)[Mar 10 - Mar 11](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=2026-03-10&endDate=2026-03-11) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=2026-03-11&endDate=2026-03-12)[Mar 11 - Mar 12](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=2026-03-11&endDate=2026-03-12) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000347957&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) ## Cities near Patuxent River ![Boardwalk in Solomon's Island Maryland on the Patuxent River](https://images.trvl-media.com/place/8609/947b7dcc-5bfe-4811-a48f-0a3d352e37b3.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Lexington Park ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Lexington Park Hotels ](https://www.expedia.com/Lexington-Park-Hotels.d8609.Travel-Guide-Hotels) - [Hotels near Patuxent River Naval Air Station ](https://www.expedia.com/Patuxent-River-Naval-Air-Station-Hotels.0-l553248621561074007-0.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Lexington Park ](https://www.expedia.com/Lexington-Park-Hotels-Pet-Friendly-Hotel.0-0-d8609-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Lexington Park ](https://www.expedia.com/Lexington-Park-Hotels-Hotels-With-Indoor-Pool.0-0-d8609-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - 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