Saint James City Vacation Rentals

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Our top choices for Saint James City vacation rentals

Tiny home glamping unit in pine island on a 6 acre property

Tiny home glamping unit in pine island on a 6 acre property
2.0 star property
Saint James City
10.0 out of 10, Exceptional, (1)
"Wonderful setting, terrific host, just right for our one night stay!"
United States
A P.
$134 nightly
The price is $147
Jan 6 - Jan 7, 2026
Total with taxes and fees
Tiny home glamping unit in pine island on a 6 acre property

Glamping in pine island, Charming 1-bedroom cabin in welcoming Saint James City

Glamping in pine island, Charming 1-bedroom cabin in welcoming Saint James City
Saint James City
$142 nightly
The price is $156
Jan 6 - Jan 7, 2026
Total with taxes and fees
Glamping in pine island, Charming 1-bedroom cabin in welcoming Saint James City

Cozy 2-bedroom downstairs unit in a house in Saint James City Pine Island

Cozy 2-bedroom downstairs unit in a house in Saint James City Pine Island
Saint James City
$333 nightly
The price is $368
Jan 6 - Jan 7, 2026
Total with taxes and fees
Cozy 2-bedroom downstairs unit in a house in Saint James City Pine Island

Tropical Getaway in St. James City – 3BR/2BA w/ Boat Ramp Access Nearby!

Tropical Getaway in St. James City – 3BR/2BA w/ Boat Ramp Access Nearby!
Manatee Bay
$691 nightly
The price is $762
Dec 31 - Jan 1, 2026
Total with taxes and fees
Tropical Getaway in St. James City – 3BR/2BA w/ Boat Ramp Access Nearby!

3-bedroom house in charming Saint James City with Canal Views!

3-bedroom house in charming Saint James City with Canal Views!
Saint James City
10.0 out of 10, Exceptional, (4)
"We had a great short stay this trip down to St James City. We love SJC and this house is a easy walk to our favorite restaurant. The best way I can describe this house is spa like. It is a very nice, comfortable house and if nothing else stay here for the shower! It had everything and was well equipped with just about anything you may need, down to the yoga mats. We had a few questions at check in and the host Britt was quick to respond and help us out. We like that the house is pet friendly as...
United States
Tracy L.
$533 nightly
The price is $587
Jan 4 - Jan 5, 2026
Total with taxes and fees
3-bedroom house in charming Saint James City with Canal Views!

StudioRes Fort Myers Airport

StudioRes Fort Myers Airport
3.0 star property
Fort Myers
9.0 out of 10, Wonderful, (20)
"Loved stay here!!! "
United States
Melissa
$114 nightly
The price is $127
Jan 6 - Jan 7, 2026
Total with taxes and fees
StudioRes Fort Myers Airport

Delightful Luxury Suite In The Heart Of Fort Myers

Delightful Luxury Suite In The Heart Of Fort Myers
Daniels Corridor
9.6 out of 10, Exceptional, (45)
"This is a great place, the owners are so nice and helpful with everything great place to stay. We were very pleased with this beautiful place. Shopping, restaurants and over all cool and clean place. "
United States
Hugo B.
$163 nightly
The price is $179
Jan 3 - Jan 4, 2026
Total with taxes and fees
Delightful Luxury Suite In The Heart Of Fort Myers

Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (226)
"Room was very clean, and spacious. Very convenient location for Ft. Myers’s beach and Sanibel. "
United States
ANNA
$108 nightly
The price is $121
Dec 31 - Jan 1, 2026
Total with taxes and fees
Lazy Cuckoo Inn

Cozy Home-Centrally located-pet friendly 10min from airport & 2min from FGCU

Cozy Home-Centrally located-pet friendly 10min from airport & 2min from FGCU
San Carlos Park
8.6 out of 10, Excellent, (10)
"Very convenient location for us"
United States
Julia M.
$211 nightly
The price is $233
Jan 14 - Jan 15, 2026
Total with taxes and fees
Cozy Home-Centrally located-pet friendly 10min from airport & 2min from FGCU

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
Matlacha
8.8 out of 10, Excellent, (269)
"Super clean! Super cute and easy for two. It is close to the road so we hear traffic, but the white noise helped with that. Communication was flawless! Would stay again. "
United States
Rhonda
$207 nightly
The price is $222
Jan 11 - Jan 12, 2026
Total with taxes and fees
Matlacha Tiny Village

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
$417 nightly
The price is $465
Jan 7 - Jan 8, 2026
Total with taxes and fees
Sundial Beach Resort & Spa

Modern boho 2bed 2bath home, 8 mins to downtown cape and near beach.

Modern boho 2bed 2bath home, 8 mins to downtown cape and near beach.
Pelican
9.4 out of 10, Exceptional, (38)
"Everything was as listed! My husband and I had a great stay while visiting friends. Location was perfect and the space was super cozy! Would definitely recommend!"
United States
julie l.
$274 nightly
The price is $301
Jan 4 - Jan 5, 2026
Total with taxes and fees
Modern boho 2bed 2bath home, 8 mins to downtown cape and near beach.

Edison Beach House

Edison Beach House
3.5 star property
Fort Myers Beach
9.4 out of 10, Exceptional, (1597)
"Awesome stay "
United States
mary
$213 nightly
The price is $238
Jan 11 - Jan 12, 2026
Total with taxes and fees
Edison Beach House

Hibiscus House Bed Breakfast Citrus Room

Hibiscus House Bed Breakfast Citrus Room
2.0 star property
Fort Myers River District
10.0 out of 10, Exceptional, (1)
"Absolutely beautiful room and amenities and the breakfast was delicious and with so many options. Loved the communication and cannot wait to come back! "
United States
Crissa
$199 nightly
The price is $221
Jan 3 - Jan 4, 2026
Total with taxes and fees
Hibiscus House Bed Breakfast Citrus Room

Summerwinds Ct Cul De Sac Bside Duplex a few miles from Ft Myers Beach & Sanibel

Summerwinds Ct Cul De Sac Bside Duplex a few miles from Ft Myers Beach & Sanibel
Iona
9.4 out of 10, Exceptional, (26)
"Perfect spot for all shopping and short drive to the beach! "
United States
Maria S.
$268 nightly
The price is $295
Dec 31 - Jan 1, 2026
Total with taxes and fees
Summerwinds Ct Cul De Sac Bside Duplex a few miles from Ft Myers Beach & Sanibel

Studio#1-Back Bay Sunsets in Matlacha

Studio#1-Back Bay Sunsets in Matlacha
Matlacha
9.0 out of 10, Wonderful, (11)
"The location and the property were both ideal for our getaway. "
United States
Trent
$185 nightly
The price is $204
Jan 22 - Jan 23, 2026
Total with taxes and fees
Studio#1-Back Bay Sunsets in Matlacha

Waterfront Condo with Pool & Boat Slip

Waterfront Condo with Pool & Boat Slip
Caloosahatchee
9.8 out of 10, Exceptional, (33)
"What a fabulous place!! Was surprised about the homey feel! Neighbors were wonderful and everyone was welcoming!! Can't wait to go back!!"
United States
Sherry V.
$344 nightly
The price is $378
Jan 10 - Jan 11, 2026
Total with taxes and fees
Waterfront Condo with Pool & Boat Slip

Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!

Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!
Pelican
9.6 out of 10, Exceptional, (54)
"Every time excellent in every way!!!"
United States
Kim G.
$285 nightly
The price is $314
Jan 3 - Jan 4, 2026
Total with taxes and fees
Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs
4.0 star property
Bonita Springs
9.2 out of 10, Wonderful, (744)
"Room great clean, staff great.loved pool"
United States
Dennis
$251 nightly
The price is $280
Jan 6 - Jan 7, 2026
Total with taxes and fees
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Lovers Key Resort

Lovers Key Resort
3.0 star property
Fort Myers Beach
8.8 out of 10, Excellent, (1019)
"The condo was great. Beautiful location and wonderful room."
United States
Jason
$316 nightly
The price is $353
Jan 3 - Jan 4, 2026
Total with taxes and fees
Lovers Key Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Saint James City Hotel Reviews

Find out more about Saint James City

Everything you need to know about Saint James City vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Saint James City vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Saint James City vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Saint James City vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Saint James City. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Saint James City in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $121 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Saint James City rentals

At Expedia, we put the best Saint James City vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Saint James City rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Saint James City vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Saint James City. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Saint James City?

Yes, we give you a choice of vacation rentals close to the most popular local attractions in Saint James City, or you can choose a more remote option if you're looking for a relaxing stay. Saint James City is known for its seafood restaurants.

What's the top vacation rental in Saint James City?

North Captiva Point House - Boat/Water Taxi Only **NEWLY RENOVATED **: This vacation home rental near Saint James City is located on the beach and has a balcony, a barbecue grill, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

How many vacation rentals are there in Saint James City?

Expedia has 55 vacation rentals for your stay in Saint James City.

What can I see and do in Saint James City?

While exploring the area, visit family-friendly sights like Jungle Golf Ft. Myers, or get outside and enjoy nature at J. N. Ding Darling National Wildlife Refuge. In the larger area, you’ll find Key West Express and Dunes Golf and Tennis Club.

What are vacation rentals like in Saint James City?

Vacation rentals are privately owned properties you can reserve for several days or more in Saint James City. Vacation rentals feature amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a great choice for a family trip or a small group gathering.