Photo by Hideki Yamagata

Find hotels in San Francisco, Panama City from $50

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Discover 1,324 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (3041)
"The internet connection in my cel phone did not work"
The price is $120
includes taxes & fees
$109 per night
Oct 14 - Oct 15
Hotel Riu Plaza Panama
Decapolis Hotel Panama City
4.0 star property
8.4 out of 10, Very Good, (1002)
"Good price but not too options for dinner near there "
The price is $88
includes taxes & fees
$80 per night
Oct 16 - Oct 17
Decapolis Hotel Panama City
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very Good, (631)
"Loved this hotel we stayed a week . Breathtaking was amazing!"
The price is $157
includes taxes & fees
$143 per night
Sep 29 - Sep 30
Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
3.5 star property
9.2 out of 10, Wonderful, (1597)
"Location and food was great.Bar service wasn t the best."
The price is $108
includes taxes & fees
$99 per night
Oct 3 - Oct 4
Plaza Paitilla Inn Hotel
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1001)
"The hotel was nice the bathrooms in the hotel were very dirty. "
The price is $202
includes taxes & fees
$183 per night
Oct 11 - Oct 12
JW Marriott Panama
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (980)
"The Staff was top notch/they took care of my every need."
The price is $175
includes taxes & fees
$159 per night
Oct 4 - Oct 5
Waldorf Astoria Panama
Novotel Panama City
4.0 star property
9.0 out of 10, Wonderful, (1002)
"The service was awesome and kind! The food was amazing good and healthy! The staff was great in all areas to accommodate our needs and stay! Love Novotel "
The price is $97
includes taxes & fees
$88 per night
Sep 29 - Sep 30
Novotel Panama City
Principe Hotel and Suites
3.0 star property
8.8 out of 10, Excellent, (1043)
"Great location "
The price is $50
includes taxes & fees
$44 per night
Oct 24 - Oct 25
Principe Hotel and Suites
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1001)
"This is an excellent hotel, from the staff service up to the room, everything was excellent. We liked the fact that there was a shopping mall at walkable distance and also that there were some good restaurants also nearby."
The price is $117
includes taxes & fees
$106 per night
Oct 1 - Oct 2
Ramada Plaza By Wyndham Panama Punta Pacífica
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1000)
"Muy buen sitio para hospedarse, estuve 3 noches por trabajo. Me apoyaron con la habitacion antes de la hora de check-in a un fee considerable, la habitacion muy amplia, bano y regadera OK, buen room service."
The price is $153
includes taxes & fees
$139 per night
Sep 28 - Sep 29
Hilton Panama
W Panama
5.0 star property
8.8 out of 10, Excellent, (1001)
"Clean and well laid out"
The price is $175
includes taxes & fees
$159 per night
Oct 6 - Oct 7
W Panama
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (305)
"Olinka manager the best, good breakfast, delicious mojitos.... the breeze and the view from the pool area was espactaculR"
The price is $302
includes taxes & fees
$275 per night
Oct 1 - Oct 2
Sofitel Legend Casco Viejo, Panama City
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"The rooftop pool is amazing"
The price is $158
includes taxes & fees
$144 per night
Oct 4 - Oct 5
Marriott Panama Hotel
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (312)
"The key cards gave alot of trouble to use. When I arrived there were no towels or iron in the room but they brought it after I made the request. Other than that the area is very convenient, the room was spacious and comfortable, and overall very good value for money."
The price is $72
includes taxes & fees
$66 per night
Oct 2 - Oct 3
Hospedium Princess Hotel Panama
Riande Urban Hotel
3.5 star property
8.6 out of 10, Excellent, (1001)
"Nice property "
The price is $76
includes taxes & fees
$69 per night
Sep 26 - Sep 27
Riande Urban Hotel
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, (978)
"Good and clean room Friendly staff "
The price is $144
includes taxes & fees
$131 per night
Oct 13 - Oct 14
Las Americas Golden Tower Panama
MARINN PLACE Financial District
3.5 star property
9.2 out of 10, Wonderful, (105)
"Clean and tidy place. There are restaurants and pharmacy nearby, about 3-4 minutes walk. They also helped us organize tours. We would stay here again on our next visit to Panama! "
The price is $80
includes taxes & fees
$73 per night
Oct 9 - Oct 10
MARINN PLACE Financial District
TRYP by Wyndham Panamá Centro
3.5 star property
9.0 out of 10, Wonderful, (1002)
"I really enjoyed my stay here. The staff were very friendly and helpful. The hotel is located in a great area, with shops and restaurants and the train within walking distance. "
The price is $76
includes taxes & fees
$69 per night
Oct 2 - Oct 3
TRYP by Wyndham Panamá Centro
Summit Rainforest & Golf Resort
4.0 star property
8.4 out of 10, Very Good, (1000)
"Hiking trails. Loved the butterfly and frog enclosures."
The price is $96
includes taxes & fees
$87 per night
Sep 26 - Sep 27
Summit Rainforest & Golf Resort
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"Excellent service as well the breakfast and the kiddness of the people. Without hesitation I will be back again to this Hotel"
The price is $164
includes taxes & fees
$149 per night
Sep 29 - Sep 30
Bristol Panama, a Registry Collection Hotel
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Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza By Wyndham Panama Punta Pacífica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Aloft Panama and Plaza Paitilla Inn Hotel.

How many hotels will I find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 204 San Francisco hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.

What is there to do in this Panama City neighborhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Omar Torrijos Recreational Park, Colonial Religious Art Museum, and Bingo 90. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.