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The Chase Park Plaza Royal Sonesta St. Louis
4.5 out of 5
1.1 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $179 per night from Dec 16 to Dec 17
$179
per night
Dec 16 - Dec 17
4.4/5 Excellent! (1,002 reviews)
Beautiful Place
"This is my go-to hotel in St. Louis if you stay in the Central West End (CWE). It is next to beautiful Forest Park, Barnes-Jewish Hospital and a number of great restaurants. The view from the rooms of the park are spectacular! The rooms are spacious, and the elevators are fast. The Lobby is fabulous ..."

Reviewed on Nov 21, 2022

The Chase Park Plaza Royal Sonesta St. Louis
AC Hotel St. Louis Central West End
2.5 out of 5
1.1 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $122 per night from Dec 18 to Dec 19
$122
per night
Dec 18 - Dec 19
4.5/5 Wonderful! (166 reviews)
"East walk to decent restaurants.modern design. Rooms have great sized windows most that overlook parking garage unfortunately."

Reviewed on Nov 25, 2022

AC Hotel St. Louis Central West End
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 out of 5
1 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $78 per night from Dec 11 to Dec 12
$78
per night
Dec 11 - Dec 12
3.1/5 (1,001 reviews)
"It was a great stay it usually is just this time the remote for tv didn't work I had to get up and down to use buttons on tv"

Reviewed on Nov 20, 2022

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

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Drury Inn & Suites St. Louis Forest Park
3 out of 5
1.1 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $135 per night from Dec 8 to Dec 9
$135
per night
Dec 8 - Dec 9
4.6/5 Wonderful! (1,000 reviews)
"Older building but nice and very clean. Beds could be updated. Overall, a good stay."

Reviewed on Nov 14, 2022

Drury Inn & Suites St. Louis Forest Park
CozySuites Central West End
2.5 out of 5
1.2 mi from St. Louis Science Center
The price is $59 per night from Dec 5 to Dec 6
$59
per night
Dec 5 - Dec 6
3.5/5 Good! (17 reviews)
"The stay was good only if I were here on better terms. I’m from Philadelphia and my brother drives a tractor trailer long distance and was in ST Louis ICU. The hotel had every amenity and set up pretty well. The only problem I had was I extended one more day and the key code didn’t work from 11 am. ..."

Reviewed on Nov 26, 2022

CozySuites Central West End
Kasa Forest Park St. Louis
3.5 out of 5
1.3 mi from St. Louis Science Center
4.4/5 Wonderful! (69 reviews)
"The apartment was very nice and clean. Everything was contactless and very easy for check-in and check-out. i would use a Kasa property again."

Reviewed on Dec 1, 2022

Kasa Forest Park St. Louis
The Cheshire
4 out of 5
1.6 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $127 per night from Jan 1 to Jan 2
$127
per night
Jan 1 - Jan 2
4.1/5 Very Good! (1,000 reviews)
Overnight getaway!
"Just an overnight getaway. Lovely hotel in a great location. The check-in staff was super nice. The room was clean and comfortable. I was given a free upgrade to my room, which was particularly nice. The onsite and very historic bar was really busy so, unfortunately, I was not able to eat there."

Reviewed on Nov 28, 2022

The Cheshire
Angad Arts Hotel
4 out of 5
1.8 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $110 per night from Jan 4 to Jan 5
$110
per night
Jan 4 - Jan 5
4.4/5 Wonderful! (1,001 reviews)
Unique, Outside the Box, Best. Staff. Ever.
"Fun hotel! The staff here is The Best. We got in very late. We were greeted at the door, and the front desk was so friendly even though it was a half hour before check in closed. The room was super clean and relaxing. It was very refreshing to have a real thermostat instead of the typical heater ..."

Reviewed on Nov 28, 2022

Angad Arts Hotel
Moonrise Hotel
4 out of 5
2.2 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $179 per night from Dec 11 to Dec 12
$179
per night
Dec 11 - Dec 12
4.6/5 Wonderful! (1,005 reviews)
"Comfortable, clean and cute room! Friendly checkin with Justin! We’ve stayed here a couple of times in the past and will be back!"

Reviewed on Dec 1, 2022

Moonrise Hotel
The Charles F. Knight Center
2.5 out of 5
2.2 mi from St. Louis Science Center
The price is $152 per night from Dec 18 to Dec 19
$152
per night
Dec 18 - Dec 19
4.7/5 Exceptional! (80 reviews)
"It was great."

Reviewed on Oct 11, 2022

The Charles F. Knight Center
Guest Host Motel
2 out of 5
2.4 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $54 per night from Dec 5 to Dec 6
$54
per night
Dec 5 - Dec 6
1.9/5 (133 reviews)
Grateful safe haven after a day of travel.
"Helpful and friendly staff! Small town older feel kind of stay in a big city. Well worth the price; if in need."

Reviewed on Jul 16, 2022

Guest Host Motel
Courtyard by Marriott St. Louis Downtown West
3 out of 5
2.3 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $113 per night from Dec 23 to Dec 24
$113
per night
Dec 23 - Dec 24
4.2/5 Excellent! (898 reviews)
"Nice place"

Reviewed on Oct 6, 2022

Courtyard by Marriott St. Louis Downtown West
Pear Tree Inn St. Louis Near Union Station
3 out of 5
2.4 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $108 per night from Dec 8 to Dec 9
$108
per night
Dec 8 - Dec 9
4.2/5 Very Good! (1,000 reviews)
Highly recommend!!!!
"All the staff were beyond friendly and helpful with any questions asked. I definitely enjoyed chatting with the staff as well. My room was clean and if I needed anything it was done right away. The hotel is also in a very convenient location as well."

Reviewed on Nov 28, 2022

Pear Tree Inn St. Louis Near Union Station
Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 out of 5
2.4 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $107 per night from Dec 18 to Dec 19
$107
per night
Dec 18 - Dec 19
4.5/5 Wonderful! (428 reviews)
"The convenience to the Metro station was very helpful."

Reviewed on Nov 20, 2022

Fairfield Inn & Suites by Marriott St. Louis Downtown
Drury Inn St. Louis at Union Station
3 out of 5
2.5 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $117 per night from Dec 11 to Dec 12
$117
per night
Dec 11 - Dec 12
4.6/5 Exceptional! (1,024 reviews)
"Freindly clean. Great location for sight seeing"

Reviewed on Nov 20, 2022

Drury Inn St. Louis at Union Station
OYO Hotel St. Louis Downtown City Center MO
3.5 out of 5
2.8 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $69 per night from Dec 23 to Dec 24
$69
per night
Dec 23 - Dec 24
3.3/5 (1,154 reviews)
"Oyó is in a cool building that is conveniently located. Plenty of parking in the garage. We enjoyed our stay with our dogs."

Reviewed on Nov 27, 2022

OYO Hotel St. Louis Downtown City Center MO
The Last Hotel
4.5 out of 5
2.9 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $145 per night from Dec 6 to Dec 7
$145
per night
Dec 6 - Dec 7
4.4/5 Wonderful! (880 reviews)
"This was the best hotel I have stayed in a while! I loved everything about it! The staff was absolutely amazing! The room was a total vibe. I could have laid in that bed all day!"

Reviewed on Dec 2, 2022

The Last Hotel
Live by Loews - St.Louis
4 out of 5
3.2 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $129 per night from Dec 18 to Dec 19
$129
per night
Dec 18 - Dec 19
4.5/5 Wonderful! (651 reviews)
"Only clean the room one day in all my stay and trying to charge 2 items of my account and I never used."

Reviewed on Nov 28, 2022

Live by Loews - St.Louis
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
3.4 mi from St. Louis Science Center
Fully refundableReserve now, pay when you stay
The price is $108 per night from Dec 8 to Dec 9
$108
per night
Dec 8 - Dec 9
4.8/5 Exceptional! (1,799 reviews)
"The parking is tight, but secure. We enjoyed the free breakfast and happy hour food. I would stay here again."

Reviewed on Nov 30, 2022

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
3.4 mi from St. Louis Science Center
Fully refundable
The price is $104 per night from Dec 28 to Dec 29
$104
per night
Dec 28 - Dec 29
4.1/5 Very Good! (2,299 reviews)
"Great view of the arch."

Reviewed on Nov 28, 2022

Hyatt Regency St. Louis at The Arch
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St. Louis Science Center hotels information

Number of reviews 16607
Accommodation 1404 hotels
Lowest Price $54
Highest Price $179

Hotels near Other St. Louis Attractions

Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, check out the 122 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near St. Louis Science Center?

Home2 Suites by Hilton St. Louis/Forest Park is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers free breakfast and an indoor pool. It's located just a short 0.5 mi (0.8 km) from St. Louis Science Center. Other good options within a short distance include Hampton Inn & Suites St. Louis at Forest Park and DoubleTree by Hilton St. Louis Forest Park.

What top hotels near St. Louis Science Center are known for their enhanced cleaning?

DoubleTree by Hilton St. Louis Forest Park, located just 19 minutes' walk from St. Louis Science Center, is a 4-star hotel offering property cleaning with disinfectant, contactless check-out, and hand sanitizer for guests. If you're looking for a wallet-friendly option, Hampton Inn & Suites St. Louis at Forest Park is a 2.5-star hotel that offers enhanced cleaning measures and is just a short 13-minute walk away. For more choices, browse all properties close to St. Louis Science Center with enhanced sanitizing measures.

How many hotels will I be able to find near St. Louis Science Center?

Expedia has 122 hotels and other accommodations within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available near St. Louis Science Center.

Where can I learn more about changing or cancelling my trip in the area near St. Louis Science Center?

To access more information about changing or cancelling your stay near St. Louis Science Center, go to https://www.expedia.com/service/.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, Missouri History Museum, and St. Louis Art Museum feature captivating exhibits. St. Louis Union Station, Sheldon Concert Hall, and Anheuser-Busch Brewery are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at Fox Theater, Peabody Opera House, and The Muny Theater.

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