St Mary Vacation Rentals

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for St Mary vacation rentals

A single-story house with a front porch, a garage, and a well-maintained lawn.

1. Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve

Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve
Saint Mary
9.8 out of 10, Exceptional, (12 reviews)
"The house was very clean. It's located in a quiet and safe neighborhood. It was well stocked with cooking utensils. It was pet friendly with a secure fenced backyard. The host was responsive and accommodating. We stayed here while we were in town for work and would stay here again."
United States
Deborah H.
$370 nightly
The price is $407
Nov 15 - Nov 16
Total with taxes and fees
Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve
A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

2. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.4 out of 10, Exceptional, (12 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
$98 nightly
The price is $112
Nov 8 - Nov 9
Total with taxes and fees
The Atrium - A Boutique Hotel
A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.

3. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (119 reviews)
"Recomend this location"
United States
Jose
$128 nightly
The price is $145
Dec 7 - Dec 8
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A white two-story house with a covered porch, a chimney, and a small garden area with chairs and a table.

4. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (296 reviews)
"Absolutely beautiful place to stay!! Very clean!"
United States
Jimmy B.
$167 nightly
The price is $188
Nov 17 - Nov 18
Total with taxes and fees
Beautiful Modern Loft In Wine Country!
Exterior

5. Cozy 2-bedroom cottage in charming Ste. Genevieve

Cozy 2-bedroom cottage in charming Ste. Genevieve
Ste. Genevieve
9.8 out of 10, Exceptional, (9 reviews)
"Great location!"
United States
Katie M.
$143 nightly
The price is $156
Dec 1 - Dec 2
Total with taxes and fees
Cozy 2-bedroom cottage in charming Ste. Genevieve
A cozy kitchen with two chairs, a small table with snacks, a coffee machine, and a view through a large window.

6. Vallee Suite at Baetje Farms

Vallee Suite at Baetje Farms
Bloomsdale
9.8 out of 10, Exceptional, (6 reviews)
"It was beautiful, quite and everything we expected!! Thanks for a great stay!!"
United States
Heather
$129 nightly
The price is $129
Nov 8 - Nov 9
Total with taxes and fees
Vallee Suite at Baetje Farms
A room with two chairs, a table with a fruit platter, a hanging light fixture, and a view through a window with a curtain.

7. Amoureux Suite at Baetje Farms

Amoureux Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (1 review)
$129 nightly
The price is $129
Nov 11 - Nov 12
Total with taxes and fees
Amoureux Suite at Baetje Farms
A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

8. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
$295 nightly
The price is $338
Nov 8 - Nov 9
Total with taxes and fees
Urban Lofts
A small, single-story building with a porch, a covered outdoor seating area, and a stone foundation.

9. 5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana

5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
Ste. Genevieve
10.0 out of 10, Exceptional, (4 reviews)
"Perfect size cabin to get away and enjoy nature sitting on front porch. Very clean with all the amenities you need. Erin was very nice and prompt response to any of my questions."
United States
Matt H.
$241 nightly
The price is $258
Nov 8 - Nov 9
Total with taxes and fees
5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
A modern kitchen with dark wood cabinets, a central island, and a brick wall.

10. Downtown Urban Loft #9

Downtown Urban Loft #9
Perryville
10.0 out of 10, Exceptional, (8 reviews)
"The Zen atmosphere made it really relaxing and the spa bathroom was incredible"
United States
Hunter
$259 nightly
The price is $299
Nov 9 - Nov 10
Total with taxes and fees
Downtown Urban Loft #9
A small, single-story building with a porch, red chairs, and a fan.

11. 5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana

5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
New Offenburg
10.0 out of 10, Exceptional, (2 reviews)
"This was one of the best places I’ve ever stayed. Owner thought of everything and it was so comfortable. The space was perfect, extra blankets, both types of coffee makers, firewood on site. This is a very new property and everything was immaculate and clean. Was easy to navigate check-in and house was so cute! Would definitely recommend to anyone heading to St Gen or any of surrounding areas."
United States
Carole J.
$241 nightly
The price is $258
Nov 8 - Nov 9
Total with taxes and fees
5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
A spacious loft with exposed brick walls, large windows, a kitchen with bar seating, and a ceiling fan.

12. Downtown Urban Loft #1

Downtown Urban Loft #1
Perryville
$257 nightly
The price is $297
Nov 8 - Nov 9
Total with taxes and fees
Downtown Urban Loft #1
A modern cabin with a wooden deck, a spiral staircase, and a fireplace.

13. New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp
Perryville
10.0 out of 10, Exceptional, (9 reviews)
"Absolutely stunning oasis. Thank you, Waylon & Kaci, for such a beautifully-crafted, unique paradise."
United States
Brett H.
$486 nightly
The price is $514
Dec 2 - Dec 3
Total with taxes and fees
New! Luxury Meets Nature - TreeRise at BaseCamp
A wooden treehouse with a glass window, surrounded by dense forest.

14. TreeLoft at BaseCamp

TreeLoft at BaseCamp
Perryville
10.0 out of 10, Exceptional, (5 reviews)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
$486 nightly
The price is $514
Nov 24 - Nov 25
Total with taxes and fees
TreeLoft at BaseCamp
A hot tub with a wooden deck surrounding it, a window above, and a view of trees outside.

15. Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.

Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
Ste. Genevieve
10.0 out of 10, Exceptional, (63 reviews)
"Wonderful place to stay in Ste Genevieve wine country"
United States
Nicholas S.
$338 nightly
The price is $362
Nov 10 - Nov 11
Total with taxes and fees
Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
A two-story cylindrical building with a covered porch and a welcoming sign.

16. Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
10.0 out of 10, Exceptional, (160 reviews)
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
United States
Anthony S.
$322 nightly
The price is $361
Nov 8 - Nov 9
Total with taxes and fees
Silo Farm Haus- located in the heart of wine country!
A modern house with a stone facade, large windows, and a porch with two chairs.

17. Coeur de la Crème Suite at Baetje Farms

Coeur de la Crème Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (3 reviews)
"It was super cozy and relaxed, the kind of place that makes you want to slow down and just hang out. Really warm vibe, almost like a little hidden getaway"
United States
Eric C.
$134 nightly
The price is $134
Nov 10 - Nov 11
Total with taxes and fees
Coeur de la Crème Suite at Baetje Farms
A modern outdoor seating area with Adirondack chairs and a fire pit, surrounded by a gravel patio.

18. THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek

THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek
Ste. Genevieve
10.0 out of 10, Exceptional, (13 reviews)
"Lovely place, communicative owners, would definitely stay there again!"
United States
Jana R.
$240 nightly
The price is $257
Nov 10 - Nov 11
Total with taxes and fees
THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek
A compact living space with a sofa, dining table, kitchen area, and a ceiling fan.

19. Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.4 out of 10, Exceptional, (11 reviews)
"Host was very helpful and accommodating! Very cute and small house, perfect for our weekend stay! "
United States
Amber P.
$130 nightly
The price is $141
Nov 9 - Nov 10
Total with taxes and fees
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Interior

20. The Cabin at Charleville

The Cabin at Charleville
Ste. Genevieve
$365 nightly
The price is $365
Nov 8 - Nov 9
Total with taxes and fees
The Cabin at Charleville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St Mary Hotel Reviews

A row of single-story houses with attached garages, a paved driveway, and a clear sky.
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve
Ste Genevieve

10/10 Excellent

Very clean, fresh and comfortable. It’s budget friendly and no frills facility There is no in-room coffee maker, but coffee available in the lobby.
United States
Ron and Paula
Reviewed October 23, 2026
Microtel Inn & Suites by Wyndham Sainte Genevieve

Find out more about St Mary

Everything you need to know about St Mary vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St Mary vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St Mary vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St Mary vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St Mary. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St Mary in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $112 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St Mary rentals

At Expedia, we put the best St Mary vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St Mary rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St Mary vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St Mary. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find vacation rentals in St Mary?

Yes, you can find vacation rentals close to the most popular local attractions in St Mary, or you can select a secluded option if you want a relaxing place to stay.

What's the top vacation rental in St Mary?

Private Hot Tub + Fire Pit | 4BR/2Bth Ranch | 10 Min to Historic Ste. Genevieve by Timber Oaks Vacation Rentals: Visitors give good reviews to this St Mary vacation home rental, which offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation. Our travelers also rate Missouri Castle w/ Private Lake, Pool & 100 Acres! as a favorite home for rent in St Mary.

What’s there to see and do in St Mary?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Popeye Museum and Felix Valle House State Historic Site.

What are vacation rentals like in St Mary?

Vacation rentals are private accommodations you can reserve for a short or long stay in St Mary. Vacation rentals feature extras like laundry facilities and kitchens so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.

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