A historical building with a brick tower and columns, surrounded by palm trees and a horse.

St. Marys Vacation Rentals

Q: What are some of the best vacation home rentals in St. Marys?

The Villas of Amelia Island : This vacation home rental outside of St. Marys is located on the beach and has an indoor pool, a furnished balcony, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a coffee maker to make your meal-planning easier. It offers a terrace, a garden, and a selection of games so you can immerse yourself in your vacation.

Dates

November 2026

December 2026

Check prices for these dates

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Our top choices for St. Marys vacation rentals

A two-story building with a balcony and a wooden staircase.

1. #I Stylish Bungalow Loft - DT Near to Waterfront

St. Marys

Evelyn F.

$190 nightly

Nov 9 - Nov 10

Total with taxes and fees

A bedroom with a bed, a window, a mirror, and a wardrobe.

2. #F 2-Bedroom Apt DT - Steps from Shops & Dining

St. Marys

Jessica W.

$205 nightly

Nov 9 - Nov 10

Total with taxes and fees

A bedroom with a bed, a TV, a ceiling fan, and a window.

3. #B Loft Downtown! Huge 2-Bedroom

St. Marys

Gail E.

$231 nightly

Nov 9 - Nov 10

Total with taxes and fees

4. #G 2-Story, Modern Rustic Apt in Cntrl Downtown

St. Marys

Jennifer M.

$254 nightly

Nov 9 - Nov 10

Total with taxes and fees

A bedroom with a bed, a window with curtains, a mirror, and a door leading to a bathroom.

5. #A Industrial Studio Loft Downtown!

St. Marys

Rachel S.

$231 nightly

Nov 9 - Nov 10

Total with taxes and fees

A modern living room with a grey sofa, a white coffee table, and a painting on the wall.

6. Stylish, Spacious 3 Bedroom Home - FREE BIKES-

St. Marys

John R.

$345 nightly

Nov 15 - Nov 16

Total with taxes and fees

A living room with a sectional sofa, a wooden coffee table with a plant, a ceiling fan, and a kitchen area with a granite countertop.

7. Adorable coastal home right downtown!

Saint Marys

MELISA S.

$301 nightly

Nov 22 - Nov 23

Total with taxes and fees

A modern kitchen with dark cabinets, stainless steel appliances, and wooden flooring.

8. #D Walk to Waterfront & Dining | Downtown King Suite

St. Marys

Amanda H.

$183 nightly

Nov 9 - Nov 10

Total with taxes and fees

9. Comfort Meets Southern Charm

St. Marys

Sarah R.

$237 nightly

Nov 29 - Nov 30

Total with taxes and fees

A living room with a sofa, a coffee table, a TV on a stand, and a window with blinds.

10. Wonderful 3 Bedroom 2 Bath

St. Marys

Karen K.

$326 nightly

Nov 9 - Nov 10

Total with taxes and fees

A view of a grassy area with trees and a body of water in the background.

11. Fox Hollow Haven Where the river meets the wild

Saint Mary's

$123 nightly

Nov 28 - Nov 29

Total with taxes and fees

A hotel room with a bed, a nightstand, and a window with curtains.

12. 1 King Bed | Non-Smoking, Micfridge

KINGSLAND

Anonymous traveler

$33 nightly

Nov 16 - Nov 17

Total with taxes and fees

A modern kitchen with a flat-screen TV, a large window, and a dining area with a table and chairs.

13. Beach 5 Villas - Immaculate 300 steps from the Ocean

Fernandina Beach

Chris

$242 nightly

Nov 9 - Nov 10

Total with taxes and fees

A spacious kitchen with a large island, pendant lighting, and a modern design.

14. Coastal Luxe Apt Near Fernandina Bch/Amelia Island/JAX Airport & I-95 to DWTN.

Yulee

Tomi D.

$251 nightly

Nov 10 - Nov 11

Total with taxes and fees

A modern living room with a sofa, coffee table, and a dining area with a kitchen in the background.

15. Entire Townhome Minutes from Beach and Airport

Yulee

colleen l.

$270 nightly

Nov 23 - Nov 24

Total with taxes and fees

A balcony with wooden chairs and a table, a potted plant with flowers, and a view of the sea and buildings.

16. Ocean Lodge Resort

St. Simons Island

Sean

$137 nightly

Nov 10 - Nov 11

Total with taxes and fees

A modern kitchen with white cabinetry, a stainless steel stove, and a microwave.

17. Visit Amelia Island Florida

Yulee

Joan H.

$285 nightly

Nov 14 - Nov 15

Total with taxes and fees

A kitchen with a central island, bar stools, a refrigerator, and a microwave.

18. Visit Fernandina Beach/Amelia Island and surrounding areas

Yulee

Jonathan L.

$278 nightly

Nov 15 - Nov 16

Total with taxes and fees

A covered outdoor area with a wooden floor, a wicker chair, a red table, and a white bench.

19. The Nest 2BR/2BA condo + Pool & short walk to the beach

Fernandina Beach

Linda B.

$283 nightly

Nov 9 - Nov 10

Total with taxes and fees

A covered outdoor area with a wooden deck, white chairs, and a view of a tree-lined area.

20. 3-bedroom condo in gorgeous Fernandina Beach

Fernandina Beach

Jeremy H.

$285 nightly

Nov 16 - Nov 17

Total with taxes and fees

View all properties

Find vacation rentals that suit your style

Top St. Marys Hotel Reviews

A porch with wooden rocking chairs and benches, a ceiling fan, and a view of trees.

Spencer House Inn Bed & Breakfast

St. Marys

10/10 Excellent

Very quiet. Room was perfect. Towels lux! BUT...I wish the staff (not kitchen) was more visible. I found myself hunting them. Breakfast was wonderful. Continental and eggs cooked to order and delish. They can also accommodate you if you arrive after 8 pm food wise. It's absolutely beautiful. Many rooms to choose from. Lovely living room and wrap around porch. Perfect if spending the day at Cumberland Island and you don't want to drive home. They can also pack you a lunch to take with...

Frances

A porch with white railings, a swing chair, a table, and potted plants.

Goodbread House Bed & Breakfast Inn

St. Marys

10/10 Excellent

This was a lovely little bed and breakfast in downtown St. Mary's - just steps from where you catch the ferry for Cumberland Island. The staff was lovely and made us feel welcome for our brief stay. They do make up a special breakfast in the morning, something different each day, so tell them if you have special dietary restrictions. I felt bad that I had not told them I was vegan, but my travelling companions thoroughly enjoyed the sausage egg casserole and yogurt with fresh fruit, and they...

Brenda

A lobby with a reception desk, blue sofas, and a tiled floor.

SureStay Plus Hotel by Best Western St Marys Cumberland

St. Marys

10/10 Excellent

Nancy

A two-story house with a porch, a flag, and a well-maintained garden.

Hoyt House Amelia Island

Fernandina Beach Historic District

10/10 Excellent

This is a wonderful restoration of a 1905 home. The staff is awesome and makes the stay really enjoyable. The floors creek but the bed is comfortable and the breakfasts gourmet quality. Bikes are available, there is a pool and hot tub, plenty of parking. It is a wonderful escape from the standard hotels. We loved it. And we met a lot of really nice visitors as well. Great place that we will return to.

Cecelia & Nick

An outdoor patio area with a pool, surrounded by trees and plants. There are several tables and chairs under umbrellas.

Blue Heron Inn

Fernandina Beach Historic District

10/10 Excellent

Anonymous traveler

An outdoor patio area with wicker chairs, a round table, and a fire pit.

TownePlace Suites Jacksonville Airport

Northside

10/10 Excellent

Michael

A courtyard with wicker furniture, a pool, and a building with balconies.

Village Inn and Pub - Adults Only

Downtown St. Simons Island

10/10 Excellent

Beautiful room with luxury touches and perfect walkable location to great restaurants and shopping. Room turnover service every day, which is rare since Covid. No elevator, so keep that in mind if you get a 2nd floor room. The continental breakfast reminded me of what you get in Europe--fresh fruit and pastries. In room Nespresso coffee maker sure beats the Keurig-types. I would definitely stay here again.

Kathy J

A grand staircase with a wooden handrail and white balusters, leading to a second floor. A chandelier hangs from the ceiling, and a sign reads "WELCOME TO THE SUN SHINE STATE".

Hampton Inn and Suites Amelia Island Historic Harbor Front

Fernandina Beach Historic District

10/10 Excellent

Susan

Beach 5 Villas - Immaculate 300 steps from the Ocean

Fernandina Beach

10/10 Excellent

Brianna

An outdoor patio area with a fire pit, seating, and a covered section with tables and chairs.

Home2 Suites by Hilton Fernandina Beach Amelia Island, FL

Fernandina Beach

10/10 Excellent

LINDA

Residence Inn by Marriott Amelia Island

Fernandina Beach

10/10 Excellent

The grounds and lobby were very nice. I have stayed at a lot of hotels that start out this way and them the rooms do not measure up. This WAS NOT the case here. We opened the door to an immediate wow factor. The layout was great and the room was very clean and nicely decorated. It was very comfortable but most importantly...QUIET!!! Unlike other hotels, there was no noise from other rooms and minimal noise from the hallway. The breakfast selection was vast and very good. I WOULD SUGGEST THIS...

LeAnna

A spacious lobby with a central black and white marble floor, wooden flooring, a chandelier, and a seating area with chairs.

B&B HOTEL Jacksonville Airport – Newly Renovated!

Northside

10/10 Excellent

Omar

A dining area with multiple tables and chairs, a patterned rug, and a bright yellow accent wall.

Hampton Inn Amelia Island at Fernandina Beach

Fernandina Beach

10/10 Excellent

I absolutely loved our stay! It was above and beyond our expectations!! I wasn’t sure how it would be but I can honestly say I would stay here every time I visit Amelia Island! It was so clean, comfortable and very nice! They provided everything you could possibly need with toiletries and gave us a gift of water bottles and travel info upon arrival. The staff went above and beyond to be so friendly and caring with every detail. The cleaning staff did an impeccably good job and the breakfast was...

Scott

Find out more about St. Marys

Everything you need to know about St. Marys vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Marys vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Marys vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Marys vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Marys. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Marys in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $142 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Marys rentals

At Expedia, we put the best St. Marys vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Marys rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Marys vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Marys. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Are there vacation rentals in St. Marys?

Yes, there are vacation rentals in St. Marys near St. Marys Railroad Museum, or you can select a more secluded option if you'd like a relaxing place to stay. Our travelers say St. Marys has a good selection of restaurants. Make sure you have time to check out the waterfront while you're in the area.

What are some of the best vacation home rentals in St. Marys?

The Villas of Amelia Island: This vacation home rental outside of St. Marys is located on the beach and has an indoor pool, a furnished balcony, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a coffee maker to make your meal-planning easier. It offers a terrace, a garden, and a selection of games so you can immerse yourself in your vacation.

How many vacation rentals will I find in St. Marys?

Expedia has 50 vacation rentals for your stay in St. Marys.

What’s there to see and do in St. Marys?

Cultural attractions include St. Marys Submarine Museum and St. Marys Railroad Museum, whereas Crooked River State Park is one spot to enjoy nature. While here, Cumberland Island Ferry and Cumberland Island National Seashore are other places worth a visit.

What’s a vacation rental in St. Marys like?

A vacation rental is a private property you can stay in for several days or longer in St. Marys. Vacation rentals feature amenities like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family trip.

St. Marys Vacation Rentals

Check prices for these dates

Our top choices for St. Marys vacation rentals

1. #I Stylish Bungalow Loft - DT Near to Waterfront

2. #F 2-Bedroom Apt DT - Steps from Shops & Dining

3. #B Loft Downtown! Huge 2-Bedroom

4. #G 2-Story, Modern Rustic Apt in Cntrl Downtown

5. #A Industrial Studio Loft Downtown!

6. Stylish, Spacious 3 Bedroom Home - FREE BIKES-

7. Adorable coastal home right downtown!

8. #D Walk to Waterfront & Dining | Downtown King Suite

9. Comfort Meets Southern Charm

10. Wonderful 3 Bedroom 2 Bath

11. Fox Hollow Haven Where the river meets the wild

12. 1 King Bed | Non-Smoking, Micfridge

13. Beach 5 Villas - Immaculate 300 steps from the Ocean

14. Coastal Luxe Apt Near Fernandina Bch/Amelia Island/JAX Airport & I-95 to DWTN.

15. Entire Townhome Minutes from Beach and Airport

16. Ocean Lodge Resort

17. Visit Amelia Island Florida

18. Visit Fernandina Beach/Amelia Island and surrounding areas

19. The Nest 2BR/2BA condo + Pool & short walk to the beach

20. 3-bedroom condo in gorgeous Fernandina Beach

Find vacation rentals that suit your style

Top St. Marys Hotel Reviews

Spencer House Inn Bed & Breakfast

10/10 Excellent

Find out more about St. Marys

Everything you need to know about St. Marys vacation rentals

St. Marys vacation rentals: An excellent choice for every season

How to find incredible deals on St. Marys rentals

Frequently Asked Questions

Are there vacation rentals in St. Marys?

What are some of the best vacation home rentals in St. Marys?

How many vacation rentals will I find in St. Marys?

What’s there to see and do in St. Marys?

What’s a vacation rental in St. Marys like?

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